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    Analysis of multiple secondary outcomes in a clinical trial leads to an increased probability of at least one false significant result among all secondary outcomes studied. In this paper, we question the notion that that if no multiplicity adjustment has been applied to multiple secondary outcome analyses in a clinical trial, then they must necessarily be regarded as exploratory. Instead, we…

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    • It is also very important for us to educate ourselves regarding the interpretation of secondary outcomes. ⁦@pomyers⁩, #TAVI-SAVR Multiple secondary outcome analyses: precise interpretation is important | Trials | Full Text https://t.co/T92wdwygKk