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Mashup Score: 77Patient-Centered Home Hemodialysis: Approaches and... : Clinical Journal of the American Society of Nephrology - 14 day(s) ago
important when customizing a prescription. Finally, an understanding of the different home HD machines currently approved for use at home and their different attributes and limitations helps guide providers when formulating their prescriptions. In this review article, we set out to address these different aspects to help guide providers in providing a patient-centered home HD approach….
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Mashup Score: 4Race, Ethnicity, Sex, Gender, Socioeconomic Status, and... : Clinical Journal of the American Society of Nephrology - 14 day(s) ago
An abstract is unavailable. This article is available as a PDF only.
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Mashup Score: 18Kinetics of Beta2-Microglobulin with Hemodiafiltration and... : Clinical Journal of the American Society of Nephrology - 15 day(s) ago
emodialysis. The impact of hemodiafiltration on beta-2-microglobulin levels was evaluated by modeling four randomized studies of hemodiafiltration vs. hemodialysis. The impact of residual kidney function on beta-2-microglobulin was tested by comparing results of previously reported measured data with model predictions. Results: In the low-flux and high-flux arms of the HEMO study, measured median beta-2-microglobulin reduction ratios could be matched by dialyzer clearances of 5.2 and 26 ml/min, respectively. Median pre-dialysis serum beta-2-microglobulin levels were matched if generation rates of beta-2-microglobulin were set to approximately 240 mg/day. In another group of patients treated with dialyzers with increased beta-2-microglobulin clearances, measured cross-dialyzer clearances (57±28 ml/min) were used as inputs. In these studies the kinetic model estimates of intradialysis and early postdialysis serum beta-2-microglobulin levels were similar to median measured values. The mod
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Mashup Score: 13Did the SCORED Trial Get Extra Points for Kidney Outcomes?... : Clinical Journal of the American Society of Nephrology - 15 day(s) ago
An abstract is unavailable.
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Mashup Score: 3The Clinical Study of Kidney Stone Disease and the Value of ... : Clinical Journal of the American Society of Nephrology - 16 day(s) ago
An abstract is unavailable.
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Mashup Score: 36Central Body Fat Distribution and Kidney Function after... : Clinical Journal of the American Society of Nephrology - 16 day(s) ago
distribution measures are associated with long-term kidney function after donor nephrectomy. We hypothesized that higher BMI, waist circumference (WC), and waist-to-height ratio (WHtR) were associated with lower kidney function long term after donation. Methods The study population consisted of living kidney donors. BMI, WC, and WHtR were measured during donor screening. The outcome postdonation kidney function was assessed using measured GFR (mGFR) (mGFR, 125I-iothalamate infusion) at 3 months (n=1042), 5 years (n=556), and 10 years (n=210) of follow-up. Primary multivariable linear regression analyses were performed with BMI and WC and secondary analyses with WHtR. Linear mixed models were performed to investigate change in postdonation eGFR. Results The donor age was 52±11 years, and 48% were male. The mean BMI was 26.1±3.6 kg/m2, and WC was 91±11 cm. Higher predonation BMI was associated with lower mGFR throughout follow-up: −1.35 (95% confidence interval [CI], −1.95 to −0.80), −1.
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Mashup Score: 28Time is Money: Protected Time for Fellow Education : Clinical Journal of the American Society of Nephrology - 17 day(s) ago
An abstract is unavailable.
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Mashup Score: 15Evaluating ApoL1 Genetic Testing Policy Options for... : Clinical Journal of the American Society of Nephrology - 17 day(s) ago
for ApoL1 risk variants. Transplant programs have highly variable ApoL1 testing practices and need guidance on essential ApoL1 clinical policy questions. Methods We conducted a Delphi consensus panel focused on ApoL1 clinical policy questions, including who gets tested, who decides whether testing occurs, how test results are shared, who receives test results, and how test results are used. A total of 27 panelists across seven stakeholder groups participated: living kidney donors (n=4), deceased donor family members (n=3), recipients of a deceased donor kidney (n=4), recipients of a living donor kidney (n=4), nephrologists (n=4), transplant surgeons (n=4), and genetic counselors (n=4). Nineteen panelists (70%) identified as Black. The Delphi panel process involved two rounds of educational webinars and three rounds of surveys administered to panelists, who were asked to indicate whether they support, could live with, or oppose each policy option. Results The panel reached consensus on
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Transplant programs need guidance on ApoL1 clinical policy questions. This study conducted a Delphi consensus panel which generally supported policy options involving discussion and shared decision making among patients, donors, and family stakeholders https://t.co/TOMkSFBgON https://t.co/4puBIiclWU
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Mashup Score: 75Effects of SGLT2 inhibitors on cause-specific... : Clinical Journal of the American Society of Nephrology - 20 day(s) ago
An abstract is unavailable. This article is available as a PDF only.
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Mashup Score: 46Associations of Changes in Bone Turnover Markers with... : Clinical Journal of the American Society of Nephrology - 20 day(s) ago
mone, bone-specific alkaline phosphatase (BALP), intact procollagen type I N-terminal propeptide (PINP), and tartrate-resistant acid phosphatase isoform 5b (TRAP5b) measured at 0, 3, and 12 months post-transplant (N=209). Paired transiliac bone biopsies were available in a subset (n=49). Between-group differences were evaluated by Student’s t test, Wilcoxon signed-rank test, or Pearson’s chi-squared test. Results Changes in BMD varied from –22% to +17%/yr. Compared with patients with no change (±2.5%/yr), patients who gained BMD had higher levels of parathyroid hormone (236 versus 136 pg/ml), BALP (31.7 versus 18.8 μg/L), and Intact PINP (121.9 versus 70.4 μg/L) at time of transplantation; a greater decrease in BALP (−40% versus −21%) and Intact PINP (−43% versus −13%) by 3 months; and lower levels of Intact PINP (36.3 versus 60.0 μg/L) at 12 months post-transplant. Patients who lost BMD had a less marked decrease, or even increase, in Intact PINP (+22% versus −13%) and TRAP5b (−27% ve
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Writing a home hemodialysis (HD) prescription is a complex, multifactorial process. This article addresses different aspects that affect use of home HD to help guide providers in providing a patient-centered approach https://t.co/Q2NdpDWbdt https://t.co/NRb7J8bFUb