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    Precision medicine for cancer is rapidly moving to an approach that integrates multiple dimensions of the biology in order to model mechanisms of cancer progression in each patient. The discovery of multiple drivers per tumor challenges medical decision that faces several treatment options. Drug sensitivity depends on the actionability of the target, its clonal or subclonal origin and coexisting genomic alterations. Sequencing has revealed a large diversity of drivers emerging at treatment failure, which are potential targets for clinical trials or drug repurposing.

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    Taking Back Sunday - 9 month(s) ago

    1 Department of Medicine, Intermountain Medical Center, Intermountain Health, Murray, UT, USA This content is only available as a PDF. Source of Support: None. Conflict of Interest: None. Lewis MA. Taking back Sunday. This work is published under a CC-BY-NC-ND 4.0 International License. This site uses cookies. By continuing to use our website, you are agreeing to our privacy

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