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Mashup Score: 7Radio-immune response modelling for spatially fractionated radiotherapy - IOPscience - 11 day(s) ago
Radio-immune response modelling for spatially fractionated radiotherapy, Young-Bin Cho, Nara Yoon, John H Suh, Jacob G Scott
Source: iopscience.iop.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 16
Nature Communications – The spatial organization of a tumor affects how it grows and responds to treatment. Here, the authors present VALIS, a software to align sets of whole slide images (WSI)…
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 230Collective intelligence: A unifying concept for integrating biology across scales and substrates - 1 month(s) ago
Communications Biology – A Perspective on how the tools of behavioral science and the emerging field of diverse intelligence help to understand decision-making of cellular collectives in…
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 223Collective intelligence: A unifying concept for integrating biology across scales and substrates - 1 month(s) ago
Communications Biology – A Perspective on how the tools of behavioral science and the emerging field of diverse intelligence help to understand decision-making of cellular collectives in…
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 25
Dr. Ben Raphael (https://twitter.com/benjraphael) presents “Quantifying Tumor Heterogeneity Across Space and Time” as part of the #mathonco (https://twitter….
Source: www.youtube.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 4A .bib file to rule them all - 2 month(s) ago
The Mathematical Oncology Community Resource
Source: mathematical-oncology.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 19Openings - 2 month(s) ago
Jeffrey West
Source: labpages.moffitt.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 1CytoSet | Proceedings of the 12th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics - 2 month(s) ago
Single-cell flow and mass cytometry technologies are being increasingly applied in clinical settings, as they enable the simultaneous measurement of multiple proteins across millions of cells within a multi-patient cohort. In this work, we introduce CytoSet, a deep learning model that can directly predict a patient’s clinical outcome from a collection of cells obtained through a blood or tissue sample. Unlike previous work, CytoSet explicitly models the cells profiled in each patient sample as a set,
Source: dl.acm.orgCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 4
Scientific Reports – Integrative network modeling reveals mechanisms underlying T cell exhaustion
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet-
Stacey spends some time discussing these two papers: (i) Integrative network modeling reveals mechanisms underlying T cell exhaustion https://t.co/A7kIN1CWqS; (ii) Integrating mechanism-based T cell phenotypes into a model of tumor-immune cell interactions https://t.co/0cTEHJz2cE https://t.co/e1jVyWCTO7
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Mashup Score: 10Drug-induced adaptation along a resistance continuum in cancer cells - 2 month(s) ago
Advancements in rational drug design over the past decades have consistently produced new cancer therapies, but such treatments are inevitably countered through an adaptive process that fosters therapy resistance. Malignant cells achieve drug resistance through intrinsic and acquired mechanisms, rooted in genetic and non-genetic determinants. In particular, recent work has highlighted the role of intrinsic cellular heterogeneity in the emergence of transient drug-tolerant persister cells that survive drug treatment, as well as non-genetically driven cell plasticity toward stable resistance. However, these models do not account for the role of dose and treatment duration as extrinsic forces in eliciting cancer cell adaptation. Here, we show that these two components together drive the resistance of ovarian cancer cells to targeted therapy along a trajectory of cellular adaptation, that we denote the ‘resistance continuum’. We report that gradual dose exposure and prolonged treatment pro
Source: www.biorxiv.orgCategories: General Medicine News, Hem/OncsTweet
RT @CancerConnector: Radio-immune response modelling for spatially fractionated radiotherapy https://t.co/1bxIcST553 https://t.co/7UrCIBLZ…