-
Mashup Score: 161
Magnesium (Mg2+), also known as “the forgotten ion,” is the second most abundant intracellular cation and is essential in a broad range of intracellular physiological and biochemical reactions. Its deficiency, hypomagnesemia (Mg2+<1.8mg/dL), is a prevalent condition and routinely poses challenges in its management in clinical practice. Sodium/glucose cotransporter 2 (SGLT2) inhibitors have emerged as a new class of drugs with treating hypomagnesemia as their unique extraglycemic benefit. The beneficial effect of SGLT2 inhibitors on magnesium balance in patients with diabetes with or without hypomagnesemia has been noted as a class effect in recent meta-analysis data from randomized clinical trials.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
-
Mashup Score: 29
Hyponatremia is the most common electrolyte disorder and is associated with significant morbidity and mortality. This study investigated neurocognitive impairment, brain volume, and alterations in MRI-based measures of cerebral function in patients before and after treatment for hyponatremia.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
-
Mashup Score: 7Living With a Rare Glomerular Disease: A Call to Action for Early Diagnosis and Innovation in Treatment - 5 day(s) ago
My Story (Antonia’s Perspective)
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
-
Mashup Score: 3Call for Submissions: Quiz - 5 day(s) ago
Every month, AJKD features an image-based Quiz that tests readers’ acumen in resolving a diagnostic or therapeutic dilemma. All Quizzes are freely available in an online collection at AJKD.org. To …
Source: ajkdblog.orgCategories: General Medicine News, NephrologyTweet-
CALL FOR SUBMISSIONS Have you encountered a tricky case that could be submitted as a Quiz to help others learn? Cases may focus on evaluation of clinical findings/interpretation of lab values/assessment of pathologic material/radiologic images. Details: https://t.co/Srec4tMcyJ https://t.co/BB3hYWWHbp
-
-
Mashup Score: 409
Individuals with liver disease are susceptible to pathophysiological derangements that lead to kidney dysfunction. Patients with advanced cirrhosis and acute liver failure (ALF) are at risk of developing acute kidney injury (AKI). Hepatorenal syndrome type 1 (HRS-1, also called HRS-AKI) constitutes a form of AKI unique to the state of cirrhosis and portal hypertension. Although HRS-1 is a condition primarily characterized by marked renal vasoconstriction and kidney hypoperfusion, other pathogenic processes, such as acute tubular injury and renal vein congestion, can overlap and further complicate the course of HRS-1.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
-
Mashup Score: 0Unraveling Barriers in Access to Living Donor Kidney Transplantation for South Asian Canadian Populations - 6 day(s) ago
Globalization of the world and international migration have led to the development of diasporic communities and the evolution of internationally diverse countries such as Canada. As one of the most multicultural countries in the world, Canada comprises more than 8 million immigrants that roughly constitute 20% of the total Canadian population.1 Cultural, social, and religious beliefs intrinsic to these different cultures are important factors to consider as patients weigh the decision whether to seek and obtain living donor kidney transplants (LDKT).
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
-
Mashup Score: 14Highlights from the May 2024 Issue - 7 day(s) ago
Editor’s Note: We asked authors of Original Investigations to provide short plain-language summaries that would briefly summarize what inspired their study, the basic approach taken, what was…
Source: ajkdblog.orgCategories: General Medicine News, NephrologyTweet
-
Mashup Score: 38A Holistic Framework for the Evaluation of Kidney Function in a Gender-Diverse Landscape - 7 day(s) ago
The most commonly used equations to estimate glomerular filtration rate incorporate a binary male-female sex coefficient, which has important implications for the care of transgender, gender-diverse, and nonbinary (TGD) people. Whether “sex assigned at birth“ or a binary “gender identity“ is most appropriate for the computation of estimated glomerular filtration rate (eGFR) is unknown. Furthermore, the use of gender-affirming hormone therapy (GAHT) for the development of physical changes to align TGD people with their affirmed gender is increasingly common, and may result in changes in serum creatinine and cystatin C, the biomarkers commonly used to estimate glomerular filtration rate.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
-
Mashup Score: 5Development and Validation of the Rating of CKD Knowledge Among Older Adults (Know-CKD) with Kidney Failure - 8 day(s) ago
Few older adults with kidney failure engage in shared decision-making (SDM) for kidney replacement therapy. Absence of instruments assessing SDM-relevant knowledge domains may contribute to this. We assessed the reliability and validity of a new instrument, the Rating of CKD Knowledge Older Adults (Know-CKD).
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
-
Mashup Score: 12
In 1988, the American Board of Internal Medicine (ABIM) defined essential procedural skills in nephrology, and candidates for ABIM certification were required to present evidence of possessing the skills necessary for placement of temporary dialysis vascular access, hemodialysis, peritoneal dialysis, and percutaneous renal biopsy. In 1996, continuous renal replacement therapy was added to the list of nephrology requirements. These procedure requirements have not been modified since 1996 while the practice of nephrology has changed dramatically.
Source: www.ajkd.orgCategories: General Medicine News, NephrologyTweet
Review by Chintan V. Shah, @Nephro_Sparks, and Chien-Te Lee: Sodium/Glucose Cotransporter 2 Inhibitors and Magnesium Homeostasis https://t.co/UXkWrZPVhq (FREE) @DukeKidney https://t.co/Ey89UOCX7z