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    Home > Gastric Cancer > Pranob Bhattacharya Discusses a Potential New Treatment Option for Gastric Cancer Astellas Pharma US, Inc. recently announced that the European Medicines Agency has accepted the Marketing Authorization Application (MAA) for regulatory review of zolbetuximab, a first-in-class investigational Claudin 18.2 (CLDN18.2)-targeted monoclonal antibody, for the potential first-line treatment of patients with locally adv anced unresectable or metastatic HER2-negative gastric or gastroesophageal

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    • Pranob Bhattacharya, Executive Director, Gastrointestinal Cancer Global Brand Lead, @AstellasUS, talks about the dangers of gastric cancer, and how zolbetuximab may effectively treat the malignancy. https://t.co/r84q5uMS9r #gastriccancer #gioncology #zolbetuximab https://t.co/zUceJ6Rn2h

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    The addition of zolbetuximab to capecitabine and oxaliplatin significantly extended PFS and OS for patients with claudin-18.2-positive/HER2-negative locally advanced unresectable or metastatic gastric or gastroesophageal junction cancer.The results of the phase 3 GLOW study, presented during an ASCO Plenary Series session, align with those of the phase 3 SPOTLIGHT trial, which evaluated the

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    • Zolbetuximab regimen extends survival in gastric, gastroesophageal junction cancer subset. https://t.co/kbzODeeZqL #Zolbetuximab @WeillCornell @AstellasUS @MSKCancerCenter #HemOnc #OncAlert #MedEd

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    Learn more about the faculty and program for the March Plenary Series session.

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    • 🆕 @ASCO #ASCOPlenarySeries @mdmanishshah @WeillCornell GLOW🕯️trial #Zolbetuximab+Chemo in #Claudin-18.2➕(🎯CLDN18.2+) advanced/metastatic gastric or gastroesophageal junction adenocarcinoma ✅One more actionable target. #STCSM #ESOCSM https://t.co/lpOomDpaBP @OncoAlert https://t.co/8mfjC02zco

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    First-line treatment with zolbetuximab added to chemotherapy significantly extended OS and PFS among adults with certain forms of claudin-18.2-positive/HER2-negative gastric adenocarcinoma, results of the phase 3 SPOTLIGHT trial showed.Study participants, who had locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma, demonstrated a 25% reduction in risk

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    • Zolbetuximab benefits subset of patients with gastric, gastroesophageal junction cancer. https://t.co/f6oZybULVQ #GastroesophagealJunctionCancer #zolbetuximab #GastricAdenocarcinoma @AstellasUS