• Mashup Score: 2

    Experiments show ease by which organisms can evolve the ability to harness sunlight for energy

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    • Scientists engineer the first light-powered #yeast https://t.co/whN933wLtt Using #light for energy: examining the evolution of #phototrophic metabolism through synthetic construction https://t.co/I3g0Ss8p2n #synbio #syntheticbiology #vacuole #ATP #Ustilago #fungi #rhodopsin https://t.co/FtD7jbqpv7 https://t.co/FXuKn9gEY3

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    Abstract. Gene expression undergoes considerable changes during the aging process. The mechanisms regulating the transcriptional response to cellular aging rema

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    • Bari et al. employ the budding #yeast model to better understand how organisms adapt their transcriptome to promote longevity; and describe Tra1 as an important regulator of longevity via multiple mechanisms. #G3Journal | https://t.co/gfdhfikQUz https://t.co/dTxMa2UqBA

  • Mashup Score: 1

    Author summary Codon usage bias (CUB), or the unequal usage of codons of the same amino acid (i.e. synonymous codons), has been observed in species across all domains of life. CUB is known to be shaped by both non-adaptive (e.g. mutation biases) and adaptive (e.g. natural selection for translation efficiency/accuracy) evolution. A key challenge for researchers is disentangling the role of various…

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    • .@AlexCope241 & @premal_shah identify genes evolving under different non-adaptive nucleotide biases across #yeast species They find genes clustered via machine learning are also physically clustered across chromosomes #Genetics #Evolution #Genomics https://t.co/EbuLIwwkzz

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    Author summary Our skin is constantly exposed to sunlight and the ultraviolet component of it can severely damage the DNA of our chromosomes. If that damage is not efficiently repaired, the cells’ physiology becomes deregulated and very often cancer ensues. The specific molecular mechanism that will remove this damage is called nucleotide excision repair or NER. NER is conserved from humans to…

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    • New research on DNA repair: Guintini et al find transcription of non-coding RNAs, such as TERRAs, stimulates nucleotide excision repair at the #telomeres Thus, transcription of TERRAs can be a #genome stabilizing function #Genetics #Yeast #DNArepair https://t.co/H0GhOJbqBp

  • Mashup Score: 3

    Author summary Repressive structures, or heterochromatin, are seeded at specific genome sequences and then “spread” to silence nearby chromosomal regions. While much is known about the factors that seed heterochromatin, the genetic requirements for spreading are less clear. We devised a fission yeast single-cell method to examine how gene silencing is propagated by the heterochromatin spreading…

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    • New heterochromatin research: Greenstein et al find genes that specifically promote or antagonize the heterochromatin spreading process in fission #yeast Different genes are required from different seeding sites @cthrntan @TheBraunLab @ASadylab @Bazzoid https://t.co/vleVsA8rHO