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Mashup Score: 2
Researchers say study offers proof-of-concept that targeting how T cells interact with metabolites in their environment can promote better outcomes in cancer.
Source: www.genengnews.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 23New take on immunotherapy reinvigorates T cells by blocking uptake of energy-sapping cancer byproducts - 7 month(s) ago
As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells—which have lost their cancer-fighting oomph—consume this lactic acid, …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet-
New take on immunotherapy reinvigorates #TCells by blocking uptake of energy-sapping cancer byproducts @natimmunol https://t.co/fmH0UGwzkq
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Mashup Score: 12
Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study led by researchers …
Source: medicalxpress.comCategories: General Medicine News, General NewsTweet-
Metabolic reprogramming of #TCells may enhance checkpoint inhibitor therapy @WeillCornell @natimmunol https://t.co/uTq48Cj4BB
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Mashup Score: 24
Research from Radboud university medical center reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of innate …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet-
#TCells can manipulate the memory of innate immune cells, researchers show @Radboud_Uni @CellReports https://t.co/SutfSmSkq7
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Mashup Score: 195The kinase ITK controls a Ca2+-mediated switch that balances TH17 and Treg cell differentiation - 10 month(s) ago
The kinase ITK determines whether naïve T cells develop into TH17 or Treg cells.
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet-
In @SciSignal, scientists uncover how an enzyme instructs immature #Tcells whether to become proinflammatory T helper 17 cells or anti-inflammatory regulatory T cells, with implications for the study of autoimmune disorders. https://t.co/k702cSKig1 https://t.co/Fot5TM5CLB
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Mashup Score: 149The kinase ITK controls a Ca2+-mediated switch that balances TH17 and Treg cell differentiation - 10 month(s) ago
The kinase ITK determines whether naïve T cells develop into TH17 or Treg cells.
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet-
In @SciSignal, scientists uncover how an enzyme instructs immature #Tcells whether to become proinflammatory T helper 17 cells or anti-inflammatory regulatory T cells, with implications for the study of autoimmune disorders. https://t.co/k702cSKig1 https://t.co/Fot5TM5CLB
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Mashup Score: 7CD106 in Tumor-Specific Exhausted CD8+ T Cells Mediates Immunosuppression by Inhibiting TCR Signaling - 11 month(s) ago
CD106 is specifically expressed in tumor-specific exhausted CD8+ T cells and inhibits the TCR signaling pathway by reducing surface expression of the TCR/CD3 complex to suppress antitumor immunity.
Source: aacrjournals.orgCategories: General Medicine News, Oncologists1Tweet-
New in Cancer Immunology from the July 1 issue— CD106 in Tumor-Specific Exhausted CD8+ #TCells Mediates Immunosuppression by Inhibiting TCR Signaling, by Yuto Naoi et al. https://t.co/ymKnRpzAFO https://t.co/cMOXZDcdP8
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Mashup Score: 18
Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center, the Lustgarten Laboratory and Bloomberg~Kimmel Institute for Cancer Immunotherapy have …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet-
New Co-STAR #TCells show promise for treating cancers in laboratory study @sciencetm https://t.co/0XJLtQKdUW
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Mashup Score: 77Blockbuster T cells in the gut: A high-resolution view of immune modulation by the gut microbiome is presented - 11 month(s) ago
A high-resolution view of immune modulation by the gut microbiome is presented
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet-
🎉 Congratulations to @MicrobiomeTcell, winner of this year’s NOSTER & Science Microbiome Prize for developing a method by which to zero in on individual gut bacterium’s impacts on #Tcells. Learn more about the work: https://t.co/NyVYvzMSt0 https://t.co/jWIGRKxWcF
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Mashup Score: 77Blockbuster T cells in the gut: A high-resolution view of immune modulation by the gut microbiome is presented - 11 month(s) ago
A high-resolution view of immune modulation by the gut microbiome is presented
Source: www.science.orgCategories: General Medicine News, Future of MedicineTweet-
🎉 Congratulations to @MicrobiomeTcell, winner of this year’s NOSTER & Science Microbiome Prize for developing a method by which to zero in on individual gut bacterium’s impacts on #Tcells. Learn more about the work: https://t.co/NyVYvzMSt0 https://t.co/jWIGRKxWcF
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RT @CyagenBio: Cancer-Fighting Zeal Regained by Tired T Cells Deprived of Lactic Acid https://t.co/0mGB9sfAN7 via @GENbio #tcells #biotec…