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Mashup Score: 4
Purpose of Review To provide an updated review of bempedoic acid’s clinical application in lowering LDL-C in the setting of statin intolerance and the recent findings in the CLEAR Outcomes trial as well as summarize and synthesize the current state of knowledge regarding bempedoic acid while providing an in-depth analysis of the drug’s pharmacological properties, mechanism of action, clinical…
Source: SpringerLinkCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
No attenuation of vascular risk reduction between younger and older statin users
Source: www.medpagetoday.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 7Statins for primary prevention provide similar protection among older vs. younger adults - 7 month(s) ago
Older individuals appeared to derive similar magnitude of LDL lowering and CV risk reduction from statin therapy initiation vs. younger patients, according to data from a large Danish study.“Use of lipid-lowering therapy to reduce LDL cholesterol constitutes the main pharmacologic intervention strategy for both primary and secondary prevention of atherosclerotic CVD. Evidence from clinical
Source: www.healio.comCategories: Cardiology News and Journals, Latest HeadlinesTweet-
ICYMI: “Our results ... may contribute to informing future guideline recommendations and clinician-patient discussion on the clinical benefit observed from lowering LDL cholesterol among older individuals for primary prevention” @ACCinTouch #Cardiotwitter https://t.co/BlUampUysZ
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Mashup Score: 4Post-diagnostic statin use and its association with cancer recurrence and mortality in breast cancer patients: a systematic review and meta-analysis - 8 month(s) ago
AbstractBackground. Statins are widely acknowledged for their application in patients with hypercholesterolemia to reduce cardiovascular morbidity and mortality
Source: academic.oup.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0Aortic Arch Aortitis Independently Associated with Vascular Complication Risk, Study Finds - 8 month(s) ago
Aortic arch aortitis increases the odds of vascular complications by 2 times, a new study concludes, with statin use proposed as an approach to improve the prognosis of aortitis.
Source: www.crtonline.orgCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 1Statin Use in ICH Linked to Lower Risk for Subsequent Stroke - 8 month(s) ago
Observational data suggest that use of statins after intracerebral hemorrhage is linked to lower risk for recurrent stroke. Researchers call for a randomized trial of statins in these patients.
Source: www.medscape.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 5
To determine the effect of statin use during concurrent chemoradiotherapy (CCRT) on overall survival and esophageal squamous cell carcinoma (ESCC)-specific survival in patients with ESCC receiving standard CCRT.
Source: www.jto.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Statins Post-PCI: Moderate-Intensity and Add Ezetimibe? - 9 month(s) ago
The reward for avoiding high-intensity-statin monotherapy could be better safety and clinical outcomes, suggests a registry study that supports randomized evidence.
Source: www.medscape.comCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 6
Among patients receiving contemporary statins, inflammation assessed by high-sensitivity CRP was a stronger predictor for risk of future cardiovascular events and death than cholesterol assessed by LDLC. These data have implications for the selection of adjunctive treatments beyond statin therapy and suggest that combined use of aggressive lipid-lowering and inflammation-inhibiting therapies might be needed to further reduce atherosclerotic risk.
Source: www.thelancet.comCategories: Cardiologists, Latest HeadlinesTweet
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Mashup Score: 0
Background: Although statins are a class I recommendation for prevention of atherosclerotic cardiovascular disease and its complications, their use is suboptimal. Differential underuse may mediate disparities in cardiovascular health for systematically marginalized persons. Objective: To estimate disparities in statin use by race–ethnicity–gender and to determine whether these potential disparities are explained by medical appropriateness of therapy and structural factors. Design: Cross-sectional analysis. Setting: National Health and Nutrition Examination Survey from 2015 to 2020. Participants: Persons eligible for statin therapy based on 2013 and 2018 American College of Cardiology/American Heart Association blood cholesterol guidelines. Measurements: The independent variable was race–ethnicity–gender. The outcome of interest was use of a statin. Using the Institute of Medicine framework for examining unequal treatment, we calculated adjusted prevalence ratios (aPRs) to estimate disp
Source: www.acpjournals.orgCategories: Hem/Oncs, Latest HeadlinesTweet-
.@NIH-funded study shows that #disparities in #statin use for several race–ethnicity–gender groups are not explained by measurable differences in medical appropriateness of therapy, access to health care, and #SES. #NHANES #guidelines @NIDDKgov @NIH_NHLBI https://t.co/dwlipgtm3I https://t.co/WeySqhh8HF
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👇 Check it out! Here’s an up-to-date review on Bempedoic acid and all the latest trials: https://t.co/iF1svkaDdd. #cholesterol #LDL #bempedoicacid #statin #myalgias #CLEAROutcomes #prevention #cardiology