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ScienceHow SARS-CoV-2 first adapted in humans - 1 day
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# SARSCoV2
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bioRxivSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in late 2019 and spread globally to cause the COVID-19 pandemic. Despite the constant accumulation of...
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Finally, I want to thank everyone in our wonderful team, Damien Richard, Liam Shaw, @CedricCSTan1, @ChrisJ_Owen, @misac42, our guest star @RobLanfear and my wonderful colleague @LucyvanDorp. 12/ https://t.co/fw4ExQUPfZ - view on twitter
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Among all major #SARSCoV2 clades, we estimate B.1.1.7 to be most transmissible. We observe a subtle, but highly consistent trend for transmissibility of #SARSCoV2 lineages to decay over time, likely due to the accumulation of deleterious mutations. 8/ https://t.co/fw4ExQUPfZ https://t.co/fw4ExQUPfZ - view on twitter
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We observe two step changes in the estimated transmissibility of #SARSCoV2 over time. It first increased with the emergence of the D614G haplotype in early 2020, and then again with the emergence of the 501Y VoCs (B.1.1.7) in the second half of 2020. 7/ https://t.co/fw4ExQUPfZ https://t.co/fw4ExQUPfZ - view on twitter
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#sarscov2
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Science AdvancesThe impact of relaxing interventions on human contact patterns and SARS-CoV-2 transmission in China - 2 days
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Nonpharmaceutical interventions to control SARS-CoV-2 spread have been implemented with different intensity, timing, and impact on transmission. As a result, post-lockdown COVID-19 dynamics are...
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While social interactions increased in 4 Chinese cities after #COVID19 lockdown restrictions were lifted in the winter and spring of 2020, they remained low enough to control #SARSCoV2 transmission, according to a new study in @ScienceAdvances. https://t.co/CUqk1UbGk7 https://t.co/CUqk1UbGk7 - view on twitter
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GEN - Genetic Engineering and Biotechnology NewsHuman Organ Chips Shift Amodiaquine from Old Antimalarial to Promising COVID-19 Treatment - 1 day
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Human organ chip-based drug testing identified that the antimalarial drug amodiaquine has inhibiting effects against...
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Human Organ Chips Shift Amodiaquine from Old Antimalarial to Promising #COVID19 Treatment The antimalarial drug amodiaquine was found to inhibit #SARSCoV2 infection when tested in human organ chips. Learn more: https://t.co/PMQOKvVc2e #organonchip #organchips https://t.co/PMQOKvVc2e - view on twitter
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GEN - Genetic Engineering and Biotechnology NewsCOVID-19-related Loss of Smell and Taste Linked to Viral Staying Power in the Human Nose - 4 hours
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A new study examines the nasal lining in patients with COVID-19 reporting loss of smell and detected SARS-CoV-2 viral particles and inflammation in multiple...
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Researchers have now explained the mechanisms involved in the loss of smell (anosmia) in patients infected with #SARSCoV2 at different stages of the disease. Learn more about their findings: https://t.co/PlfmZ4Op5u #COVID19 https://t.co/PlfmZ4Op5u - view on twitter
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Fred HutchAddressing a ‘massive unmet need’ in COVID-19 treatment - 22 hours
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Fred Hutch physician-scientists at the COVID-19 Clinical Research Center are engaged in several studies of drugs that have the potential to prevent infection by...
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Even as vaccine distribution expands, it is important as ever to find medications that can take the lethal edge off #SARSCoV2. Researchers at the #COVID19 Clinical Research Center are testing drugs that can stop the disease before symptoms become severe. https://t.co/tWMlscTre6 - view on twitter
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JAMA NetworkThis study aims to describe an association between the Pfizer-BioNTech (BNT162b2) vaccine and decreased risk of symptomatic and asymptomatic infections with SARS-CoV-2 in hospital...
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We know vaccines vastly reduce symptomatic disease & hospitalization. @JAMA_current shows Pfizer vaccine also reduced asymptomatic infection among hospital workers, suggesting significantly lower spread of #SARSCoV2 following a 2-dose regimen. Great news! https://t.co/2ZVwjLXACL - view on twitter
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DNA ScienceOn the Anniversary of the Pandemic, Considering the Bioweapon Hypothesis – DNA Science - 11 hours
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A year ago, the Director General of the World Health Organization, Tedros Adhanom Ghebreyesus, delivered the message that would divide time:...
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#SARSCoV2 fits general criteria of a #bioweapon: it spreads easily even among the asymptomatic, resists environmental changes, can be transported and intentionally released in a targeted manner, and can cause severe disease and death. https://t.co/VuX2C2ymzz https://t.co/VuX2C2ymzz - view on twitter
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GEN - Genetic Engineering and Biotechnology NewsSingle-Cell, Spatial Analysis Creates COVID-19 Tissue Atlases - 5 hours
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Single-cell, spatial analysis of autopsy samples from patients who succumbed to COVID-19 offers key insights into systemic disease...
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A team developed a foundational dataset consisting of tissue atlases that elucidate the biological impact of severe #SARSCoV2 infection in the body. Learn more: https://t.co/26oyfShfUW https://t.co/26oyfShfUW - view on twitter
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Renal and Urology News12 Cases of CVST Reported for Ad26.COV2.S Vaccine in the US – Renal and Urology News - 2 days
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Time from vaccination to symptom onset varied from 6 to 15 days; initial presentation was headache in 11...
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12 Cases of CVST Reported for Janssen/Johnson & Johnson Vaccine in the US https://t.co/sn1z8PGVpF #COVID19 #SARSCoV2 - view on twitter
Viruses need entry proteins to penetrate the cells where they will replicate. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) version is called the...
A new #SciencePerspective takes a closer look at how #SARSCoV2 first adapted in humans. Learn more: https://t.co/5qO8rHl0SY #WeekendReads - view on twitter