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    AbstractBackground:. Previous epidemiologic studies found inconsistent associations between fish consumption and renal cell carcinoma (RCC). Although the consumption of n-3 polyunsaturated fatty acids (PUFA) was reported to protect against the development of some types of cancer, little is known regarding its association with RCC.Methods:. We investigated the association between fish and n-3 PUFA consumption and RCC risk using the Japan Public Health Center-based Prospective Study. We examined data from 84,063 eligible Japanese participants aged 45 to 74 years who responded to a validated food frequency questionnaire for Cohort I in 1995 and Cohort II in 1998. The participants were followed-up until 2013. HRs and 95% confidence intervals (CI) were estimated using a multivariable-adjusted Cox proportional hazard model, and the exposure level was categorized into quartiles.Results:. Among the 1,272,298 person-years of follow-up, 262 cases of newly diagnosed RCC were identified. The multi

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    • Takahashi et al study the association between fish consumption and #RenalCellCarcinoma and find a positive association between n-3 polyunsaturated fatty acids and RCC risk in Japanese who consume higher amounts of fish than Western populations. https://t.co/nyHx9fFDqa https://t.co/zJHuawI5ly