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Mashup Score: 3Deadly virus structures point toward new avenues for vaccine design - 11 month(s) ago
By comparing the structures of protein complexes from different lineages of the dangerous Lassa virus, a Scripps Research team identified new antibodies and vaccine targets.
Source: EurekAlert!Categories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 4
Charge patterning in disordered regions of transcriptional regulators mediates selective partitioning into MED1IDR condensates for gene activation.
Source: CellCategories: Healthcare Professionals, Latest HeadlinesTweet-
Functional partitioning of transcriptional regulators by patterned charge blocks https://t.co/i9A4xUVTJc @CellCellPress #MED1 #transcription #promoter #enhancer #Mediator #transcripitionfactor #proteinstructure #proteinengineering #PolII https://t.co/lGtXLi5ry0
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Mashup Score: 2
DeepMind’s 350,000 structures include 44% of all human proteins
Source: Science | AAASCategories: Healthcare Professionals, Latest HeadlinesTweet-
New public database of #AI-predicted protein structures could transform biology @ScienceMagazine https://t.co/s4lEcdGlfF #structuralbiology #proteinstructure #DeepMind #RoseTTAFold "#AlphaFold produced structures for nearly 44% of all human proteins" Low-down with key links.
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Mashup Score: 5
Proteins are essential to life, and understanding their structure can facilitate a mechanistic understanding of their function. Through an enormous experimental effort1–4, the structures of around 100,000 unique proteins have been determined5, but this represents a small fraction of the billions of known protein sequences6,7. Structural coverage is bottlenecked by the months to years of…
Source: NatureCategories: Healthcare Professionals, Latest HeadlinesTweet-
#DeepMind and a rival release dueling code for protein-folding #AI Re: @nature: https://t.co/dcqL8g5otD Highly accurate #proteinstructure prediction with #AlphaFold https://t.co/m6ak7Bl820
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By comparing the structures of #protein complexes from different lineages of the dangerous Lassa virus, a @scrippsresearch team identified new #antibodies and #vaccine targets #glycoproteins #proteinstructure #antibodytherapy https://t.co/NuW5VdYdFg