• Mashup Score: 10

    Patients with germline SDHD pathogenic variants (encoding succinate dehydrogenase subunit D; ie, paraganglioma 1 syndrome) are predominantly affected by head and neck paragangliomas, which, in almost 20% of patients, might coexist with paragangliomas arising from other locations (eg, adrenal medulla, para-aortic, cardiac or thoracic, and pelvic). Given the higher risk of tumour multifocality and bilaterality for phaeochromocytomas and paragangliomas (PPGLs) because of SDHD pathogenic variants than for their sporadic and other genotypic counterparts, the management of patients with SDHD PPGLs is clinically complex in terms of imaging, treatment, and management options.

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    • #Clinical #consensus #guideline on the management of #phaeochromocytoma and #paraganglioma in patients harbouring germline SDHD pathogenic variants https://t.co/PJSiZnUXga #PPGLs #FREE to read with registration (also FREE) https://t.co/Ft03vxQZwd

  • Mashup Score: 13

    Patients with germline SDHD pathogenic variants (encoding succinate dehydrogenase subunit D; ie, paraganglioma 1 syndrome) are predominantly affected by head and neck paragangliomas, which, in almost 20% of patients, might coexist with paragangliomas arising from other locations (eg, adrenal medulla, para-aortic, cardiac or thoracic, and pelvic). Given the higher risk of tumour multifocality and bilaterality for phaeochromocytomas and paragangliomas (PPGLs) because of SDHD pathogenic variants than for their sporadic and other genotypic counterparts, the management of patients with SDHD PPGLs is clinically complex in terms of imaging, treatment, and management options.

    Tweet Tweets with this article
    • Clinical consensus guideline on the management of #phaeochromocytoma and #paraganglioma in patients harbouring germline SDHD pathogenic variants https://t.co/PJSiZnUXga #PPGLs #FREE to read with registration (also FREE)

  • Mashup Score: 8

    Patients with germline SDHD pathogenic variants (encoding succinate dehydrogenase subunit D; ie, paraganglioma 1 syndrome) are predominantly affected by head and neck paragangliomas, which, in almost 20% of patients, might coexist with paragangliomas arising from other locations (eg, adrenal medulla, para-aortic, cardiac or thoracic, and pelvic). Given the higher risk of tumour multifocality and bilaterality for phaeochromocytomas and paragangliomas (PPGLs) because of SDHD pathogenic variants than for their sporadic and other genotypic counterparts, the management of patients with SDHD PPGLs is clinically complex in terms of imaging, treatment, and management options.

    Tweet Tweets with this article
    • Clinical consensus #guideline on the management of #phaeochromocytoma and #paraganglioma in patients harbouring germline #SDHD pathogenic variants https://t.co/PJSiZnVv5I #PPGLs FREE to read with registration (also FREE)

  • Mashup Score: 1

    The risk factors for severe COVID-19 are diverse, yet closely resemble the clinical manifestations of catecholamine excess states (eg, hypertension, cardiovascular disease, immune dysregulation, and hyperglycaemia), suggesting a potentially common basis for disease. Unfortunately, severe illness (eg, respiratory failure, compromised cardiac function, and shock) incurred by COVID-19 hinders the…

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    • #Catecholamine physiology and its implications in patients with #COVID-19 https://t.co/CAqkRHAB2t #PPGL #phaeochromocytoma #paraganglioma #neuroendocrine #COVID19 #FREE to read https://t.co/svBa2feS7S