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Mashup Score: 2Parechovirus infection in human brain organoids: host innate inflammatory response and not neuro-infectivity correlates to neurologic disease - 2 month(s) ago
Nature Communications – In comparison to PeV-A1, infection with PeV-A3 is associated with neurological illness in infants. Here, using brain organoids, the authors suggest that the innate…
Source: www.nature.comCategories: General Medicine News, Infectious DiseaseTweet
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Mashup Score: 91ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart development - 3 month(s) ago
Kostina et al. investigate how exposure to diabetes during early embryonic development affects the human heart in an innovative hPSC-derived heart organoid model. The authors discover that exposure to diabetes triggers ER stress and VLCFA dyslipidemia in the embryonic heart. Restoration of ER homeostasis and/or VLCFA levels using small molecules provided a significant degree of cardioprotection, suggesting new therapeutic alternatives.
Source: www.cell.comCategories: General Medicine News, General HCPsTweet-
Heart #organoids simulate congenital heart disease caused by pregestational diabetes. Read more in @stemcellreports: https://t.co/oGFaGFQtB2 @aaguirrecano https://t.co/e0CoZymOwf
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Mashup Score: 87ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart development - 4 month(s) ago
Kostina et al. investigate how exposure to diabetes during early embryonic development affects the human heart in an innovative hPSC-derived heart organoid model. The authors discover that exposure to diabetes triggers ER stress and VLCFA dyslipidemia in the embryonic heart. Restoration of ER homeostasis and/or VLCFA levels using small molecules provided a significant degree of cardioprotection, suggesting new therapeutic alternatives.
Source: www.cell.comCategories: General Medicine News, General HCPsTweet-
Heart #organoids simulate congenital heart disease caused by pregestational diabetes. Read more in @stemcellreports: https://t.co/oGFaGFQtB2 @aaguirrecano https://t.co/e0CoZymOwf
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Mashup Score: 85ER stress and lipid imbalance drive diabetic embryonic cardiomyopathy in an organoid model of human heart development - 4 month(s) ago
Kostina et al. investigate how exposure to diabetes during early embryonic development affects the human heart in an innovative hPSC-derived heart organoid model. The authors discover that exposure to diabetes triggers ER stress and VLCFA dyslipidemia in the embryonic heart. Restoration of ER homeostasis and/or VLCFA levels using small molecules provided a significant degree of cardioprotection, suggesting new therapeutic alternatives.
Source: www.cell.comCategories: General Medicine News, General HCPsTweet-
Heart #organoids simulate congenital heart disease caused by pregestational diabetes. Read more in @stemcellreports: https://t.co/oGFaGFQtB2 @aaguirrecano https://t.co/e0CoZymOwf
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Mashup Score: 4Organoids in endocrine and metabolic research: current and emerging applications - Nature Reviews Endocrinology - 5 month(s) ago
Organoid technologies are a potent tool for investigating human biology, modelling diseases and developing novel therapies. In this Viewpoint, experts in metabolic and endocrine research in the brain, pituitary, skeletal muscle, bone and gastrointestinal system discuss how organoids and related bioengineered systems are currently used in their field and how innovations in these technologies could…
Source: www.nature.comCategories: General Medicine News, EndocrinologyTweet-
Viewpoint: five experts discuss how #organoids and related bioengineered systems are currently used in their field and how innovations in these technologies could transform future research (£) https://t.co/WqgkB6wzR4 @gilbertlab @Tueindhoven @sanhofma https://t.co/eTfAu8XSbx
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Mashup Score: 4
Cell Symposia: Engineering development and disease in organoids
Source: cell-symposia.comCategories: General Medicine News, General NewsTweet-
Submit your #organoids research for presentation at the @CellSymposia: Engineering development and disease in organoids, August 19–21, San Diego, USA. Abstract deadline May 10. https://t.co/bKtfd56RZj https://t.co/7a28oEvDe4
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Mashup Score: 12
Cell Symposia: Engineering development and disease in organoids
Source: cell-symposia.comCategories: General Medicine News, General NewsTweet-
Meet the @CellSymposia: Engineering development and disease in #organoids organizers, Rusty Gage @salkinstitute, Magdalena Zernicka-Goetz @MZG_Lab @ZernickaGoetz @Caltech @Cambridge_Uni, Ivayla Ivanova @DevCell Christine Weber @CellStemCell https://t.co/IQeyr3qwHd https://t.co/giNRo1C95w
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Mashup Score: 16Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology - 10 month(s) ago
Integrative pharmaco-proteogenomic profiling of liver cancer organoids identifies therapeutic response signatures and predicts drug combinations.
Source: www.science.orgCategories: Future of Medicine, Latest HeadlinesTweet-
Assembling a large biobank of patient-derived #LiverCancer #organoids, researchers identify a metabolic weakness in liver tumors that can be exploited with a combination of temsirolimus and lenvatinib in vitro and in mice. https://t.co/ScgTWeTdgW @ScienceTM https://t.co/9rsZyrynMG
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Mashup Score: 2New insights into liver cancer using organoids - 1 year(s) ago
Scientists of the Princess Máxima Center for pediatric oncology and Hubrecht Institute have revealed new scientific insights into the features of fibrolamellar carcinoma (FLC), a rare type of childhood liver cancer. Their findings, published today in Nature Communications, may help in developing new drug therapies in the future. Mini organs and the ‘molecular scissor’ system CRISPR-Cas9, allowed…
Source: EurekAlert!Categories: General Medicine News, Latest HeadlinesTweet-
New insights into #livercancer using #organoids @prinsesmaximac #cancerresearch #pediatrics #CRISPRs https://t.co/HG1QIXXJun
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Mashup Score: 0Online Event - 1 year(s) ago
Brain organoids are a self-organizing three-dimensional tissue derived from stem cells that simulate the architecture and functionality of the brain. Stem-cell-derived brain organoids have been generated to model the development of multiple brain regions and to model neurodegenerative and neurodevelopmental diseases. Strategies to generate these organoids are continuing to improve to better…
Source: www.workcast.comCategories: General Medicine News, Latest HeadlinesTweet-
Did you miss Paola Arlotta @harvardstemcell, Sergiu Pasca @Stanford & Aparna Bhaduri @UCLA chat #Brain #organoids: Modeling neurodevelopment and disease? No problem, now available on demand! Register for free #CPWebinars https://t.co/2H7m43ecD5 https://t.co/bkkAg0evrx
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🔬 Researchers with Dr. Katja Wolthers from @organovir @amsterdamumc expanded their understanding of differences in PeV-A central nervous system disease using human 🧠brain #organoids and clinical isolates of the two PeV-A genotypes. @NatureComms | https://t.co/KPEOAJrVz6 https://t.co/ArSDI0t8er