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Mashup Score: 29Frontiers | The brain entropy dynamics in resting state - 16 day(s) ago
As a novel measure for irregularity and complexity of the spontaneous fluctuations of brain activities, brain entropy (BEN) has attracted much attention in r…
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Mashup Score: 14
This study aimed to elucidate the alterations in the prefrontal cortex’s functional connectivity and network topology in narcolepsy patients using functional near-infrared spectroscopy (fNIRS). Twelve narcolepsy-diagnosed patients from Guangxi Zhuang Autonomous Region’s People’s Hospital Sleep Medicine Department and 11 matched healthy controls underwent resting fNIRS scans. Functional connectivity and graph theory analyses were employed to assess the prefrontal cortex network’s properties and their correlation with clinical features. Results indicated increased functional connectivity in these adolescent and young adult patients with narcolepsy, with significant variations in metrics like average degree centrality and node efficiency, particularly in the left middle frontal gyrus. These alterations showed correlations with clinical symptoms, including depression and sleep efficiency. However, the significance of these findings was reduced post False Discovery Rate adjustment, suggesti
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Mashup Score: 1Exploring Flip Flop memories and beyond: training Recurrent Neural Networks with key insights - 16 day(s) ago
Training neural networks to perform different tasks is relevant across various disciplines. In particular, Recurrent Neural Networks (RNNs) are of great interest in Computational Neuroscience. Open-source frameworks dedicated to Machine Learning, such as Tensorflow and Keras have produced significant changes in the development of technologies that we currently use. This work contributes by comprehensively investigating and describing the application of RNNs for temporal processing through a study of a 3-bit Flip Flop memory implementation. We delve into the entire modeling process, encompassing equations, task parametrization, and software development. The obtained networks are meticulously analyzed to elucidate dynamics, aided by an array of visualization and analysis tools. Moreover, the provided code is versatile enough to facilitate the modeling of diverse tasks and systems. Furthermore, we present how memory states can be efficiently stored in the vertices of a cube in the dimensi
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Mashup Score: 9Awake brain surgery: toward optimal cognitive explorations - 17 day(s) ago
Some recent reviews have tried to compile the protocols used for surgery (Ruis, 2018;Bu et al., 2021). They involve mainly language paradigms, but not only. And teams vary in the type of tests used. These reviews report commonalities and start a way to generate a specific brain-to-task map that could guide the cognitive part of electrostimulation.What calls attention is that, in the end, a minimal set of tasks is matched to very different areas in the brain (Bu et al., 2021). For example, picture naming is suggested to be applied to the frontal lobe, the anterior temporal lobe, the posterior temporal lobe, the occipital lobe, and the parietal lobe. That is, virtually to the whole left hemisphere cortex. Furthermore, when addressing the tasks to be applied to white matter stimulation, picture naming is meant to be used to any of the major white matter tracts: the frontal aslant tract, the superior longitudinal fasciculus, the inferior fronto-occipital fasciculus, de uncinate fasciculus,
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Mashup Score: 60Scientists Discover Extensive Brain-Wave Patterns - 17 day(s) ago
Certain brain layers specialize in particular waves—which might aid understanding of neuropsychiatric disorders
Source: www.scientificamerican.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 2
IntroductionTranscutaneous spinal cord stimulation (TSCS), a non-invasive form of spinal cord stimulation, has been shown to improve motor function in indivi…
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Mashup Score: 0
IntroductionA water extract of Centella asiatica (L.) Urban [Apiaceae] (CAW) has demonstrated cognitive-enhancing effects in mouse models of Alzheimer’s dise…
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Mashup Score: 15
Estradiol, the most potent and prevalent member of the estrogen class of steroid hormones and is expressed in both sexes. Functioning as a neuroactive steroi…
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Mashup Score: 7
IntroductionSpinal cord stimulation is a common treatment option for neuropathic pain conditions. Despite its extensive use and multiple technological evolut…
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Mashup Score: 5
ADP-ribosylation plays a significant role in various biological processes including genomic stability maintenance, transcriptional regulation, energy metabolism, and cell death. Using macrodomain pull-down assay with microglia lysates and MALDI-TOF-MS analysis, we identified vimentin as a major protein highly ADP-ribosylated by the poly(ADP-ribose) polymerases-1 (PARP-1) in response to LPS. ABT-888, a potent inhibitor of PARP-1/2 blocks the disassembly and ADP-ribosylation of vimentin. PARP-1 is a highly abundant nuclear protein. Its nuclear functions in repairing DNA damages induced by various stress signals, such as inflammatory stresses, have been well studied. In contrast, limited studies have been done on the cytoplasmic role(s) of PARP-1. Our study focuses on the cytoplasmic role of PARP-1 during microglia activation. Using immunofluorescence microscopy and Western blotting, we showed that a significant amount of PARP-1 is present in the cytosol of microglia cells stimulated and
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New Research: The brain entropy dynamics in resting state: As a novel measure for irregularity and complexity of the spontaneous fluctuations of brain activities, brain entropy (BEN) has attracted much attention in resting-state functional… https://t.co/qMQjY9XPQY #Neuroscience