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Mashup Score: 14
master trials umbrella trials platform trials basket trials RCT methodology flozins SGLT2 inhibitors NephTrials RENAL LIFECYCLE Dapagliflozin
Source: NephJCCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 5#NephTrials Healthcare Social Media Analytics - 2 year(s) ago
Top Influencers of the #NephTrials healthcare social media hashtag.
Source: SymplurCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 2Mortality risk in patients on hemodiafiltration versus hemodialysis: a 'real-world' comparison from the DOPPS - PubMed - 2 year(s) ago
Our results do not support the notion that HDF provides superior patient survival. Further trials designed to test the effect of high-volume HDF (versus lower volume HDF versus HD) on clinical outcomes are needed to adequately inform clinical practices.
Source: PubMedCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 2
Background More than a third of the 65,000 people living with kidney failure in the UK attend a dialysis unit 2–5 times a week to have their blood cleaned for 3–5 h. In haemodialysis (HD), toxins are removed by diffusion, which can be enhanced using a high-flux dialyser. This can be augmented with convection, as occurs in haemodiafiltration (HDF), and improved outcomes have been reported in…
Source: BioMed CentralCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 1Effect of hemodiafiltration on measured physical activity: primary results of the HDFIT randomized controlled trial - PubMed - 2 year(s) ago
HDF did not have a statistically significant treatment effect on PA 24 h following dialysis, albeit effect sizes may be clinically meaningful and deserve further investigation.
Source: PubMedCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 4Registry-based randomised clinical trials: a remedy for evidence-based diabetes care? - Diabetologia - 2 year(s) ago
This narrative review describes a new approach to navigation in a challenging landscape of clinical drug development in diabetes. Successful outcome studies in recent years have led to new indications and guidelines in type 2 diabetes, yet the number of clinical trials in diabetes is now declining. This is due to many environmental factors acting in concert, including the prioritisation of…
Source: SpringerLinkCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 0
The next #Nephtrials discussion will feature a deep dive into convection/hemodiafiltration, and the ongoing registry based trial, H4RT
Source: NephJCCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 2
The next #Nephtrials discussion will feature a deep dive into convection/hemodiafiltration, and the ongoing registry based trial, H4RT
Source: NephJCCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 44
A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes – Full Text View.
Source: clinicaltrials.govCategories: Latest Headlines, NephrologyTweet
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Mashup Score: 0nephtrials — Blog — NephJC - 2 year(s) ago
After cluster RCTs and pragmatic trials, we will discuss the role of run in periods and what we try to achieve by having them in clinical trials. Read on. This week we discuss cluster RCTs. How…
Source: NephJCCategories: Latest Headlines, NephrologyTweet
we will be discussing the RENAL LIFECYCLES and basket trial design in a couple of hours with @RonGansevoort Summary https://t.co/L9NE1TU8lt #VisualAbstract from @deniise_am and @ISNkidneycare SoMe team Follow @manasib33 and #NephTrials for more! https://t.co/TRxPjzDyJ0