• Mashup Score: 3
    Cell-Free Circulating Tumor DNA and Epstein-Barr Virus DNA for Early Diagnosis of Epstein-Barr Virus–Associated Cancers - 8 month(s) ago

    AUTHORS’ DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I = Immediate Family Member, Inst = My Institution. Relationships may not relate to the subject matter of this manuscript. For more information about ASCO’s conflict of interest policy, please refer to www.asco.org/rwc or ascopubs.org/jco/authors/author-ce

    Source: ascopubs.org
    Categories: Hem/Onc News and Journals, Latest Headlines
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      ASCO_pubs

      🧐 #JCO #UnderstandingThePathway: Cell-Free Circulating Tumor DNA and Epstein-Barr Virus DNA for Early Diagnosis of EBV-Associated Cancers ➡️ https://t.co/5nqFru0KQO #NasopharyngealCarcinoma #lymphoma #hncsm #lymsm https://t.co/yY6jhEpt0X

  • Mashup Score: 1
    Performance and Operational Feasibility of Epstein-Barr Virus–Based Screening for Detection of Nasopharyngeal Carcinoma: Direct Comparison of Two Alternative Approaches - 8 month(s) ago

    PURPOSE Two Epstein-Barr virus (EBV)–based testing approaches have shown promise for early detection of nasopharyngeal carcinoma (NPC). Neither has been independently validated nor their performance compared. We compared their diagnostic performance in an independent population. METHODS We tested blood samples from 819 incident Taiwanese NPC cases (213 early-stage, American Joint Committee on Cancer version 7 stages I and II) diagnosed from 2010 to 2014 and from 1,768 controls from the same region, frequency matched to cases on age and sex. We compared an EBV antibody score using immunoglobulin A antibodies measured by enzyme-linked immunosorbent assay (EBV antibody score) and plasma EBV DNA load measured by real-time PCR followed by next-generation sequencing (NGS) among EBV DNA–positive individuals (EBV DNA algorithm). RESULTS EBV antibodies and DNA load were measured for 2,522 (802 cases; 1,720 controls) and 2,542 (797 cases; 1,745 controls) individuals, respectively. Of the 898 ind

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    Categories: Hem/Onc News and Journals, Latest Headlines
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      👀 EBV-antibody and EBV DNA testing are both feasible for #NasopharyngealCarcinoma detection with the blood assay performing slightly better overall ➡️ https://t.co/ngdGdrfdPK #hncsm https://t.co/ttIIVJgz5l

  • Mashup Score: 15
    Evolutionary route of nasopharyngeal carcinoma metastasis and its clinical significance - Nature Communications - 1 year(s) ago

    It is critical to understand the factors that are associated with nasopharyngeal carcinoma (NPC) progression, metastasis and response to therapy. Here, the authors analyse primary and metastatic NPC samples using bulk and single-cell sequencing, and find two distinct evolutionary routes that lead to metastasis.

    Source: Nature
    Categories: General Medicine News, Latest Headlines
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      Recently published: Lin et al. analyse primary and metastatic #NasopharyngealCarcinoma samples using bulk and #SingleCell sequencing, and find two distinct evolutionary routes that lead to #metastasis #CancerResearch @natrescancer https://t.co/q5QPYleHIY https://t.co/QzpIOAJUeT

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