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Mashup Score: 6SETBP1 sets the stage - 1 month(s) ago
In this issue of Blood, Crespiatico et al1 explore the impact of the timing (founding event vs secondary acquisition) of SETBP1 mutation on the phenotype o
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Mashup Score: 40GPR56 in GVL: marker or mechanism? - 2 month(s) ago
In the current issue of Blood, Mathioudaki et al1 use single-cell RNA sequencing to identify adhesion G-protein coupled receptor GPR56 as a marker of an an
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Mashup Score: 25Validate User - 2 month(s) ago
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Mashup Score: 59Comparing malignant monocytosis across the updated WHO and ICC classifications of 2022 - 2 month(s) ago
When reclassifying 2130 oligomonocytosis cases using the WHO and ICC 2022 classifications, 356 and 241 cases are newly classified as CMML.Compared with MD-
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Mashup Score: 23Tumor necrosis factor α promotes clonal dominance of KIT D816V+ cells in mastocytosis: role of survivin and impact on prognosis - 2 month(s) ago
KIT D816V confers resistance to TNF via BIRC5 (survivin) and promotes clonal dominance.High TNF levels are associated with inferior survival in SM.
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Mashup Score: 31Systemic mastocytosis: dying or survivin - 2 month(s) ago
In this issue of Blood, Greiner et al1 demonstrate that aberrant mast cells in systemic mastocytosis with the KIT D816V mutation release tumor necrosis factor (
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Mashup Score: 82A road map of relapse in MDS after allo-HSCT - 2 month(s) ago
In this issue of Blood, Dimitriou and colleagues report that mutational screening for malignant hematopoietic stem and progenitor cells (HSPCs) that persist aft
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Mashup Score: 34Outcomes of intensive and nonintensive blast-reduction strategies in accelerated and blast-phase MPN - 2 month(s) ago
Blast-reduction strategies in MPN-AP/BP most commonly result in reversion to chronic phase MPN with significant residual disease burden.Mutational burden remain
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Mashup Score: 29Systemic mastocytosis: dying or survivin - 2 month(s) ago
In this issue of Blood, Greiner et al1 demonstrate that aberrant mast cells in systemic mastocytosis with the KIT D816V mutation release tumor necrosis factor (
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Mashup Score: 80Mutations highly specific for secondary AML are associated with poor outcomes in ELN favorable risk NPM1-mutated AML - 2 month(s) ago
Patients with favorable-risk AML who had NPM1 mutation have poor prognosis if they also harbor mutations highly specific for sMut.Patients with sMut had better
Source: ashpublications.orgCategories: General Medicine News, Onc News and JournalsTweet
SETBP1 sets the stage https://t.co/QAph3ftElP #myeloidneoplasia