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Mashup Score: 31Systemic mastocytosis: dying or survivin - 2 month(s) ago
In this issue of Blood, Greiner et al1 demonstrate that aberrant mast cells in systemic mastocytosis with the KIT D816V mutation release tumor necrosis factor (
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Mashup Score: 82A road map of relapse in MDS after allo-HSCT - 2 month(s) ago
In this issue of Blood, Dimitriou and colleagues report that mutational screening for malignant hematopoietic stem and progenitor cells (HSPCs) that persist aft
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Mashup Score: 34Outcomes of intensive and nonintensive blast-reduction strategies in accelerated and blast-phase MPN - 2 month(s) ago
Blast-reduction strategies in MPN-AP/BP most commonly result in reversion to chronic phase MPN with significant residual disease burden.Mutational burden remain
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Mashup Score: 29Systemic mastocytosis: dying or survivin - 2 month(s) ago
In this issue of Blood, Greiner et al1 demonstrate that aberrant mast cells in systemic mastocytosis with the KIT D816V mutation release tumor necrosis factor (
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Mashup Score: 80Mutations highly specific for secondary AML are associated with poor outcomes in ELN favorable risk NPM1-mutated AML - 2 month(s) ago
Patients with favorable-risk AML who had NPM1 mutation have poor prognosis if they also harbor mutations highly specific for sMut.Patients with sMut had better
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Mashup Score: 78A road map of relapse in MDS after allo-HSCT - 2 month(s) ago
In this issue of Blood, Dimitriou and colleagues report that mutational screening for malignant hematopoietic stem and progenitor cells (HSPCs) that persist aft
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Mashup Score: 98Prognostic risk signature in patients with acute myeloid leukemia treated with hypomethylating agents and venetoclax - 2 month(s) ago
The mPRS can accurately segregate 3 groups of patients with AML with different outcomes with HMA and Ven.Patients with FLT3-ITD and NRAS/KRAS mutations have a r
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Mashup Score: 35A new SAGA for AML: targeting SGF29 in AML - 2 month(s) ago
In this issue of Blood, Barbosa et al1 discover that the chromatin reader protein SGF29 is a novel dependency for leukemias with upregulation of the MEIS1/HOX p
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Mashup Score: 26
The chromatin reader protein SGF29 is a novel epigenetic vulnerability in AML.SGF29 regulates AML oncogene transcription and KAT2A chromatin localization in AML
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Mashup Score: 57Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors - 3 month(s) ago
UBTF tandem duplications and KMT2A/menin complex co-occupy genomic targets dysregulated in UBTF-TD acute myeloid leukemias.UBTF-TD acute myeloid leukemias are s
Source: ashpublications.orgCategories: General Medicine News, Rare DiseaseTweet
Systemic mastocytosis: dying or survivin https://t.co/eOy6idk6lf #myeloidneoplasia https://t.co/ojIiRkebql