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Mashup Score: 2
Abstract. Cardiovascular diseases (CVD) are a leading cause of human death worldwide. Over the past two decades, the emerging field of cardioimmunology has demo
Source: OUP AcademicCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 0Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent FTX Locus to Promote Colon Cancer Development - 3 year(s) ago
Approximately half of all miRNA reside within intronic regions and are often cotranscribed with their host genes. However, most studies of intronic miRNA focus on individual miRNA, while conversely most studies of protein-coding and noncoding genes frequently ignore any intron-derived miRNA. We hypothesize that the individual components of such multigenic loci may play cooperative or competing…
Source: Cancer ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 0
While the molecular functions of miR-200 family have been deeply investigated, a role for these miRNAs as breast cancer biomarkers remains largely unexplored. In the attempt to clarify this, we profiled the miR-200 family members expression in a large cohort of breast cancer cases with a long follow-up (H-CSS cohort) and in TCGA-BRCA cohort. Overall, miR-200 family was found upregulated in breast…
Source: Scientific ReportsCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 4Triple Negative Breast Cancer in the Era of miRNA - 3 year(s) ago
The objective of this review is to elucidate the role of miRNAs in triple negative breast cancer (TNBC). To achieve our goal, we searched databases su…
Source: www.sciencedirect.comCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 2Systematic analysis of intronic microRNAs reveals cooperativity within the multi-component FTX locus to promote colon cancer development - 4 year(s) ago
Approximately half of all microRNA reside within intronic regions and are often co-transcribed with their host genes. However, most studies of intronic microRNA focus on individual microRNA, while conversely most studies of protein-coding and non-coding genes frequently ignore any intron-derived microRNA. We hypothesize that the individual components of such multi-genic loci may play cooperative…
Source: Cancer ResearchCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
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Mashup Score: 2The clinical potential of circulating microRNAs in obesity - 4 year(s) ago
Circulating microRNAs act as a new class of endocrine factor that can facilitate crosstalk between metabolic organs. This Review highlights obesity-associated and/or adipose tissue-enriched microRNAs and discusses their potential as biomarkers or therapeutics for obesity and related disorders.
Source: Nature Reviews EndocrinologyCategories: Endocrinology, Latest HeadlinesTweet
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Mashup Score: 1Accurate diagnosis of endometriosis using serum microRNAs - 4 year(s) ago
Endometriosis, a chronic disease that afflicts millions of women worldwide, has traditionally been diagnosed by laparoscopic surgery. This diagnostic barrier delays identification and treatment by years, resulting in prolonged pain and disease progression. Development of a noninvasive diagnostic test could significantly improve timely disease detection. We tested the feasibility of serum…
Categories: Latest Headlines, OBGYNTweet
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Mashup Score: 3Two-miRNA–based finger-stick assay for estimation of absorbed ionizing radiation dose - 4 year(s) ago
Practical, scalable approaches for measuring therapeutic or accidental ionizing radiation exposure are needed. Yadav et al. show that the expression of two miRNAs in a drop of blood allowed inference of recent gamma or neutron radiation exposure in a variety of mouse models subjected to fractionated or single acute radiation and patients with leukemia undergoing fractionated radiotherapy within a…
Source: Science Translational MedicineCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 19Two-miRNA–based finger-stick assay for estimation of absorbed ionizing radiation dose - 4 year(s) ago
Practical, scalable approaches for measuring therapeutic or accidental ionizing radiation exposure are needed. Yadav et al. show that the expression of two miRNAs in a drop of blood allowed inference of recent gamma or neutron radiation exposure in a variety of mouse models subjected to fractionated or single acute radiation and patients with leukemia undergoing fractionated radiotherapy within a…
Source: Science Translational MedicineCategories: Future of Medicine, Latest HeadlinesTweet
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Mashup Score: 3FEBS Press - 4 year(s) ago
Epigenetic regulation of cell development and fate is a very complex and intricate process. Here, we address in detail the role of DNA methylation remodelers in hematological malignancies and their r…
Source: FEBS PressCategories: Future of Medicine, Latest HeadlinesTweet
A small solution for a big problem State-of-the-art review on the roles of #immune system derived #microRNAs in the development of #CardiovascularDisease https://t.co/0SBxZgRYMR @CVR_TomaszGuzik @AlAntonopoulos @DrMikeDrozd #CVD #cardioimmunology #CardiovascularResearch https://t.co/NHzRqFz0bG