• Mashup Score: 5
    EORTC - 12 month(s) ago

    Skip to content Back to Clinical Trials Database Personalized Risk-Adapted Therapy in Post-Pubertal Patients with Newly-Diagnosed Medulloblastoma…

    Source: EORTC
    Categories: Hem/Onc News and Journals, Latest Headlines
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      EORTC

      🎉EORTC-1634-BTG #PersoMed-I academic phase II #ClinicalTrial, the first worldwide randomised trial in post-pubertal and adults newly diagnosed with #medulloblastoma, has enrolled its first two patients. 👉 https://t.co/2WFkLfgj72 #CancerResearch #ClinicalTrials #BrainCancer https://t.co/dB9ZgDy04q

  • Mashup Score: 0
    Unanswered questions in managing medulloblastoma - 1 year(s) ago

    Enrico Franceschi, MD, Ospedale Bellaria Carlo Alberto Pizzardi, Bologna, Italy, describes unmet needs in the management of medulloblastoma, including overcoming…

    Source: VJOncology
    Categories: Hem/Onc News and Journals, Latest Headlines
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      VJOncology

      #ESMOSarcomaandrarecancers23 | If you were interested in Enrico Franceschi’s (@AUSLBologna) talk on #medulloblastoma, watch our exclusive interview with him on overcoming resistance and the need to preserve fertility in patients! https://t.co/2ciTXAJVUs @myESMO #btsm

  • Mashup Score: 2
    Nanoparticles Target Medulloblastoma Tumor to Improve Drug Therapy and Reduce Toxicity - 1 year(s) ago

    Scientists developed a new drug delivery approach that uses nanoparticles to enable more effective and targeted delivery of anticancer drugs to treat brain tumors in children. The technology allows for the enhanced delivery of anticancer drugs across the blood-brain barrier to the specific locations of brain tumors, while sparing normal brain regions. Tests in mice showed that drug delivery using…

    Source: GEN - Genetic Engineering and Biotechnology News
    Categories: Future of Medicine, Latest Headlines
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      GENbio

      #Nanoparticles Target #Medulloblastoma Tumor to Improve Drug Therapy and Reduce Toxicity A new drug delivery approach uses nanoparticles to enable a more effective and targeted delivery of anticancer drugs to treat brain tumors in children. Learn more: https://t.co/WuuzDjtYWW https://t.co/rr4R8WKLFT

  • Mashup Score: 6
    Nanoparticles Target Medulloblastoma Tumor to Improve Drug Therapy and Reduce Toxicity - 1 year(s) ago

    Scientists developed a new drug delivery approach that uses nanoparticles to enable more effective and targeted delivery of anticancer drugs to treat brain tumors in children. The technology allows for the enhanced delivery of anticancer drugs across the blood-brain barrier to the specific locations of brain tumors, while sparing normal brain regions. Tests in mice showed that drug delivery using…

    Source: GEN - Genetic Engineering and Biotechnology News
    Categories: Future of Medicine, Latest Headlines
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      GENbio

      #Nanoparticles Target #Medulloblastoma Tumor to Improve Drug Therapy and Reduce Toxicity A new drug delivery approach uses nanoparticles to enable a more effective and targeted delivery of anticancer drugs to treat brain tumors in children. Learn more: https://t.co/WuuzDjtYWW https://t.co/uLLA5wmBpv

  • Mashup Score: 2
    Understanding How Childhood Brain Tumors Develop - News Center - 1 year(s) ago

    Scientists have identified a new cell type implicated in the development of medulloblastoma, according to a study published in Nature.

    Source: News Center
    Categories: Hem/Onc News and Journals, Latest Headlines
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      LurieCancer

      Scientists have identified “the regulatory network and key players for the most lethal subtype of #medulloblastoma,” the most common type of malignant childhood #braintumor. @LurieCancer’s @yuefeng_1 was a co-author of the study in @Nature. https://t.co/N0qmIaZpyk #BTSM https://t.co/zKz6nQY1Ew

  • Mashup Score: 0
    EORTC - 1 year(s) ago

    Skip to content Back to Clinical Trials Database Personalized Risk-Adapted Therapy in Post-Pubertal Patients with Newly-Diagnosed Medulloblastoma…

    Source: EORTC
    Categories: Hem/Onc News and Journals, Latest Headlines
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      EORTC

      EORTC-1634-BTG PersoMed-I academic phase II #ClinicalTrial is open for patient recruitment. First worldwide randomized trial in post-pubertal and adults newly diagnosed with #medulloblastoma. More: https://t.co/GWaBMhq2Sa @GatewayforCR @gminniti2012 #CancerResearch #BrainCancer https://t.co/HDUteGBoNj

  • Mashup Score: 2
    Dormant SOX9-positive cells facilitate MYC-driven recurrence of medulloblastoma - 2 year(s) ago

    Abstract. Relapse is the leading cause of death in patients with medulloblastoma, the most common malignant pediatric brain tumor. A better understanding of the mechanisms underlying recurrence could lead to more effective therapies for targeting tumor relapses. Here, we observed that SOX9, a transcription factor and stem cell/glial fate marker, is limited to rare, quiescent cells in high-risk…

    Source: American Association for Cancer Research
    Categories: Hem/Onc News and Journals, Latest Headlines
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      CR_AACR

      #ICYMI: SOX9 facilitates therapy escape and recurrence in #medulloblastoma via temporal inhibition of MYC/MYCN, and specifically targeting dormant SOX9-positive cells could help prevent relapse. https://t.co/FC1HuUtWMq @UU_University https://t.co/RbpneoiVkU

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