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Mashup Score: 0Effects of Cerebrovascular and Lewy Body Pathology on Parkinsonian Signs in Community-Dwelling Older Adults - 2 year(s) ago
Background and Objectives: The roles of Lewy body (LB) and separately of cerebrovascular disease (CVD) pathologies in the severity of parkinsonian signs are well recognized in old age. We investigated whether the two pathologies act synergistically to further potentiate the severity of parkinsonism beyond their separate effects. Methods: We employed postmortem data of decedents from 3…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 0DIAMOND-Lewy; DIAMOND-Lewy; Newcastle University - 2 year(s) ago
Newcastle University, Institute of Neuroscience, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, United Kingdom. Telephone: (0191) 208 1310 © 2017 Newcastle University
Source: research.ncl.ac.ukCategories: Geriatrics, Latest HeadlinesTweet
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Mashup Score: 0
Background and Objectives. Patients with Lewy body disease (LBD) often show a co-occurring Alzheimer’s disease (AD) pathology. Cerebrospinal fluid (CSF) biomarkers allow the detection in vivo of AD-related pathological hallmarks included in the AT(N) classification system. Here, we aimed to investigate whether CSF biomarkers of synaptic and neuro-axonal damage are correlated with the presence of…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet-
Via @GreenJournal: Patients with #LewyBody disease/A+T+ and those with #Alzheimers had significantly higher cerebrospinal fluid levels of synaptic and neuro-axonal biomarkers than patients with Lewy body disease/A-T- and controls: https://t.co/i3fiisQI8O #neurotwitter @AANMember https://t.co/5gJNfDMUTc
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Mashup Score: 0The terrorist inside my husband's brain - 3 year(s) ago
I am writing to share a story with you, specifically for you. My hope is that it will help you understand your patients along with their spouses and caregivers a little more. And as for the research you do, perhaps this will add a few more faces behind the why you do what you do. I am sure there are already so many.
Source: NeurologyCategories: Healthcare Professionals, Latest HeadlinesTweet
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Mashup Score: 2Neurology ® Video Journal Club: Cognitive Disorders | American Academy of Neurology Journals - 3 year(s) ago
Learn from experts in the field of neurology as they discuss Neurology journal articles in the Neurology Video Journal Club Cognitive Disorders Collection
Source: www.neurology.orgCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 11Brain Metabolism Related to Mild Cognitive Impairment and Phenoconversion in Patients With Isolated REM Sleep Behavior Disorder - 3 year(s) ago
Background and Objectives: Mild cognitive impairment (MCI) in isolated REM sleep behavior disorder (iRBD) is a risk factor for the subsequent neurodegeneration. We aimed to identify brain metabolism and functional connectivity changes related to MCI in patients with iRBD and the neuroimaging markers’ predictive value for phenoconversion. Methods: This is a prospective cohort study of iRBD…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 4Autopsy Validation of the Diagnostic Accuracy of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease - 3 year(s) ago
Background and Objectives 123I-meta-iodobenzyl-guanidine (123I-MIBG) myocardial scintigraphy is used as a diagnostic imaging test to differentiate Lewy body diseases (LBDs), including Parkinson disease and dementia with Lewy bodies, from other similar diseases. However, this imaging test lacks validation of its diagnostic accuracy against the gold standard. Our aim was to validate the diagnostic…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 5Association of the ATN Research Framework With Clinical Profile, Cognitive Decline, and Mortality in Patients With Dementia With Lewy Bodies - 3 year(s) ago
Background and Objectives The ATN framework has been developed to categorize biological processes within the Alzheimer disease (AD) continuum. Because AD pathology often coincides with dementia with Lewy bodies (DLB), we aimed to investigate the distribution of ATN profiles in DLB and associate ATN profiles in DLB with prognosis. Methods We included 202 patients with DLB from the Amsterdam…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet
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Mashup Score: 2Barriers to Treatment of Hallucinations and Delusions in People With Dementia Residing in Long-Term Care | Psychiatrist.com - 3 year(s) ago
This narrative review addresses barriers to diagnosing dementia-related psychosis, outlines the prevalence and presentation of psychosis among dementia types, and reviews current practices for treating dementia-related psychosis in long-term care.
Source: Psychiatrist.comCategories: Latest Headlines, PsychiatryTweet
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Mashup Score: 3Autopsy Validation of the Diagnostic Accuracy of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease - 3 year(s) ago
Background and Objectives: 123I-meta-iodobenzyl-guanidine (123I-MIBG) myocardial scintigraphy is employed as a diagnostic imaging test to differentiate Lewy body diseases (LBDs), including Parkinson’s disease and dementia with Lewy bodies, from other similar diseases. However, its diagnostic accuracy lacks validation compared with that of the gold standard. We aimed to validate the diagnostic…
Source: NeurologyCategories: Latest Headlines, NeurologyTweet
Via @GreenJournal: Atherosclerosis and macroscopic infarcts may interact with #LewyBody pathology, increasing the severity of #parkinsonism beyond their additive effects in older patients: https://t.co/XJJ4GntmN6 #neurotwitter #dementia @AANMember https://t.co/URLFII5tg4