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    Researchers Reveal How Receptors Treat Chronic Gut Pain - 1 year(s) ago

    It may soon be possible to treat chronic pain linked to gastrointestinal conditions like irritable bowel syndrome by specifically targeting a receptor that regulates our sensation of touch and warmth. Read on for details:

    Source: www.dynamitenews.com
    Categories: Healthcare Professionals, Latest Headlines
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      westr

      Researchers Reveal How Receptors Treat Chronic #GutPain https://t.co/l3jXkyeA98 via @DynamiteNews_ #ionchannels #IBD #Piezo2 channels expressed by #colon-innervating #TRPV1-lineage neurons mediate #visceralpain mechanical hypersensitivity @NeuroCellPress https://t.co/J7W57SGkW6

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    Building a better painkiller - 2 year(s) ago

    On a quest to develop more effective pain medicines, scientists are studying how CBD inhibits pain-sensing neurons

    Source: EurekAlert!
    Categories: Healthcare Professionals, Latest Headlines
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      westr

      Building a better #painkiller https://t.co/G25Zt0PBfh via @EurekAlert @HarvardMed #chronicpain #cannabidiol #ionchannels #pain "it is unlikely that #CBD itself will be useful as a painkiller." So much for the anecdotal patient reports and the $$$ being siphoned off them.

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    How do antidepressants treat nerve pain? - 2 year(s) ago

    Knowing how pain impulses are inhibited by tricyclic antidepressants is expected to lead to new and improved treatment options.

    Source: www.labonline.com.au
    Categories: Healthcare Professionals, Latest Headlines
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      westr

      How do [TCA] #antidepressants treat #nervepain? https://t.co/ePCDcc35kD #amitriptyline Inhibition of N-type calcium #ionchannels by tricyclic antidepressants.. ustification for their use for #neuropathicpain https://t.co/mDeQ9bns7l

  • Mashup Score: 2
    Chronic Pain Researchers Pursue New Path to Localized Relief - 2 year(s) ago

    Center for Advanced Pain Studies researchers are teaming up with colleagues on a project that received a $6.8 million grant from the National Institutes of Health.

    Source: News Center
    Categories: Healthcare Professionals, Latest Headlines
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      westr

      #ChronicPain Researchers Pursue New Path to Local Relief https://t.co/WkiukVv2M3 NIH Awards HEAL Grant to Study Novel Ways to Treat #Pain https://t.co/f1g9kmWKEA v @yalemed $11.9M grant “Site-directed #RNAediting of Nav1.7 as a novel #analgesic" #IonChannels #NeuropathicPain https://t.co/ZVJgw23vgH

  • Mashup Score: 7
    Structural insights into GIRK2 channel modulation by cholesterol and PIP2 - 3 year(s) ago

    Ion channels are important in determining neuronal excitability. Elevated cholesterol levels found in some neurodegenerative diseases can affect the function of ion channels. Mathiharan et al. take a structural and functional approach to identifying physical sites for cholesterol, and they provide details on how cholesterol potentiates ion channel activity.

    Source: Cell Reports
    Categories: Latest Headlines, Neurology
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      SinaiBrain

      NEW PUBLICATION between @paslesin @YMathiharan & @LabSkiniotis that provides details on how #Cholesterol in #Brain regulates #IonChannels & alters their function. LEARN MORE @CellReports👉 https://t.co/tJDxg5EzLj @StanfordMed @IcahnMountSinai https://t.co/RjPv9V9jFa

  • Mashup Score: 7
    Structural insights into GIRK2 channel modulation by cholesterol and PIP2 - 3 year(s) ago

    Ion channels are important in determining neuronal excitability. Elevated cholesterol levels found in some neurodegenerative diseases can affect the function of ion channels. Mathiharan et al. take a structural and functional approach to identifying physical sites for cholesterol, and they provide details on how cholesterol potentiates ion channel activity.

    Source: Cell Reports
    Categories: Latest Headlines, Neurology
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    • Profile photo of SinaiBrain
      SinaiBrain

      NEW PUBLICATION by @YMathiharan & @paslesin provides new details on how #Cholesterol in #Brain regulates #IonChannels/alters their function. Allows us to utilize site in ion channel for drug development & potentially treating #NeurodegenerativeDiseases👉https://t.co/tJDxg5EzLj https://t.co/opH7Rh0LvE

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    BPS Publications - 4 year(s) ago

    Structure Guided Pharmacology of Membrane Proteins Call for Papers: Structure Guided Pharmacology of Membrane Proteins British Journal of Pharmacology will be publishing a special ‘Themed Issue’ entitled Structure Guided Pharmacology of Membrane Proteins, with Gary Stephens and Arun K. Shukla as Guest Editors. In this issue, focused on…

    Source: British Pharmacological Society | Journals
    Categories: General Medicine Journals and Societies, Latest Headlines
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      Wiley_Health

      Be part of the @BrJPharmacol Themed Issue, Structure Guided Pharmacology of Membrane Proteins. Submit your article to British Journal of Pharmacology today. https://t.co/SDvJ5o0oD6 #pharmacology #ionchannels #transporters #drugtargets https://t.co/sYi9AbwaUo

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