-
Mashup Score: 0Mother-to-child hepatitis b transmission presents economic trade-offs - 11 month(s) ago
Expanding peripartum prophylaxis could be more cost-effective, but would likely lead to significant over-treatment.
Source: Contemporary OB/GYNCategories: Latest Headlines, OBGYNTweet
-
Mashup Score: 0
Metabolic comorbidities heightened risk for adverse liver-related events among patients with chronic hepatitis B virus, with the highest risk found among patients with multiple comorbidities, according to research. “The leading causes of death among patients with chronic HBV (CHB) are hepatocellular carcinoma and liver cirrhosis-related complications,” Lesley A. Patmore, MD, from the
Source: www.healio.comCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 1
Objective We examined the serological, virological (in serum and liver) and histological profiles in chronic hepatitis B virus (HBV) patients during and after completion of multiple dose (MD) ARC-520. Design The present phase 1b study was a multidose, open-label extension cohort of patients that had received single dose ARC-520 in our previous study. Eight patients received 4–9 4 weekly doses of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 1
Objective We examined the serological, virological (in serum and liver) and histological profiles in chronic hepatitis B virus (HBV) patients during and after completion of multiple dose (MD) ARC-520. Design The present phase 1b study was a multidose, open-label extension cohort of patients that had received single dose ARC-520 in our previous study. Eight patients received 4–9 4 weekly doses of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 0
Objective We examined the serological, virological (in serum and liver) and histological profiles in chronic hepatitis B virus (HBV) patients during and after completion of multiple dose (MD) ARC-520. Design The present phase 1b study was a multidose, open-label extension cohort of patients that had received single dose ARC-520 in our previous study. Eight patients received 4–9 4 weekly doses of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 0
Objective We examined the serological, virological (in serum and liver) and histological profiles in chronic hepatitis B virus (HBV) patients during and after completion of multiple dose (MD) ARC-520. Design The present phase 1b study was a multidose, open-label extension cohort of patients that had received single dose ARC-520 in our previous study. Eight patients received 4–9 4 weekly doses of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 0
Objective We examined the serological, virological (in serum and liver) and histological profiles in chronic hepatitis B virus (HBV) patients during and after completion of multiple dose (MD) ARC-520. Design The present phase 1b study was a multidose, open-label extension cohort of patients that had received single dose ARC-520 in our previous study. Eight patients received 4–9 4 weekly doses of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 2
Objective We examined the serological, virological (in serum and liver) and histological profiles in chronic hepatitis B virus (HBV) patients during and after completion of multiple dose (MD) ARC-520. Design The present phase 1b study was a multidose, open-label extension cohort of patients that had received single dose ARC-520 in our previous study. Eight patients received 4–9 4 weekly doses of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 0
Objective We examined the serological, virological (in serum and liver) and histological profiles in chronic hepatitis B virus (HBV) patients during and after completion of multiple dose (MD) ARC-520. Design The present phase 1b study was a multidose, open-label extension cohort of patients that had received single dose ARC-520 in our previous study. Eight patients received 4–9 4 weekly doses of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
-
Mashup Score: 0Therapeutic shutdown of HBV transcripts promotes reappearance of the SMC5/6 complex and silencing of the viral genome in vivo - 2 year(s) ago
Objective Therapeutic strategies silencing and reducing the hepatitis B virus (HBV) reservoir, the covalently closed circular DNA (cccDNA), have the potential to cure chronic HBV infection. We aimed to investigate the impact of small interferring RNA (siRNA) targeting all HBV transcripts or pegylated interferon-α (peg-IFNα) on the viral regulatory HBx protein and the structural maintenance of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet
The main strategy to reduce rates of #hepatitisB in children under age 5 years to 0.1% by 2030 has been reducing mother-to-child transmission by giving neonates a dose of #hepatitisBvirus vaccine within 24 hours of birth. https://t.co/8wuzWAvFkL