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Mashup Score: 3
Objective Braak’s hypothesis states that Parkinson’s disease (PD) originates in the gastrointestinal (GI) tract, and similar associations have been established for Alzheimer’s disease (AD) and cerebrovascular diseases (CVD). We aimed to determine the incidence of GI syndromes and interventions preceding PD compared with negative controls (NCs), AD and CVD. Design We performed a combined case-control and cohort study using TriNetX, a US based nationwide medical record network. Firstly, we compared subjects with new onset idiopathic PD with matched NCs and patients with contemporary diagnoses of AD and CVD, to investigate preceding GI syndromes, appendectomy and vagotomy. Secondly, we compared cohorts with these exposures to matched NCs for the development of PD, AD and CVD within 5 years. Results We identified 24 624 PD patients in the case-control analysis and matched 18 cohorts with each exposure to their NCs. Gastroparesis, dysphagia, irritable bowel syndrome (IBS) without diarrhoea
Source: gut.bmj.comCategories: Gastroenterology, Latest HeadlinesTweet
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Mashup Score: 1Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study - 1 year(s) ago
Background There is an increasing incidence of inflammatory bowel disease (IBD) for which environmental factors are suspected. Antibiotics have been associated with development of IBD in earlier generations, but their influence on IBD risk in adults is uncertain. Objective To assess the impact of antibiotic exposure, including dose–response, timing and antibiotic class, on the risk of IBD in all…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease on the paper by @AdamFayeMD, @KristineAllin, @manasiagrawalmd, @PREDICTIBD et al "Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study" via https://t.co/zc9bG3CpSm #GUTInTheNews https://t.co/3XgSXWY8He
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Mashup Score: 0Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study - 1 year(s) ago
Background There is an increasing incidence of inflammatory bowel disease (IBD) for which environmental factors are suspected. Antibiotics have been associated with development of IBD in earlier generations, but their influence on IBD risk in adults is uncertain. Objective To assess the impact of antibiotic exposure, including dose–response, timing and antibiotic class, on the risk of IBD in all…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease on the paper by @AdamFayeMD, @KristineAllin, @manasiagrawalmd, @PREDICTIBD et al "Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study" via https://t.co/zc9bG3CpSm #GUTInTheNews https://t.co/EfGpJiTaX5
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Mashup Score: 0Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study - 1 year(s) ago
Background There is an increasing incidence of inflammatory bowel disease (IBD) for which environmental factors are suspected. Antibiotics have been associated with development of IBD in earlier generations, but their influence on IBD risk in adults is uncertain. Objective To assess the impact of antibiotic exposure, including dose–response, timing and antibiotic class, on the risk of IBD in all…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease on the paper by @AdamFayeMD, @KristineAllin, @manasiagrawalmd, @PREDICTIBD et al "Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study" via https://t.co/zc9bG3CpSm #GUTInTheNews https://t.co/dBuQIhBBC1
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Mashup Score: 4Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study - 1 year(s) ago
Background There is an increasing incidence of inflammatory bowel disease (IBD) for which environmental factors are suspected. Antibiotics have been associated with development of IBD in earlier generations, but their influence on IBD risk in adults is uncertain. Objective To assess the impact of antibiotic exposure, including dose–response, timing and antibiotic class, on the risk of IBD in all…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease on the paper by @AdamFayeMD, @KristineAllin, @manasiagrawalmd, @PREDICTIBD et al "Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study" via https://t.co/zc9bG3CpSm #GUTInTheNews https://t.co/xra8wfEgnr
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Mashup Score: 0Non-alcoholic fatty liver disease and risk of new-onset heart failure: an updated meta-analysis of about 11 million individuals - 2 year(s) ago
Objective Recent studies reported an association between non-alcoholic fatty liver disease (NAFLD) and increased risk of new-onset heart failure (HF). However, the magnitude of the risk and whether this risk changes with severity of liver disease remains uncertain. We performed a meta-analysis of observational studies to quantify the magnitude of the association between NAFLD and risk of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease #GUTInTheNews - read the paper by Mantovani et al on "Non-alcoholic fatty liver disease and risk of new onset heart failure: an updated meta-analysis of about 11 million individuals" via https://t.co/0hSJI0AfSO #LiverTwitter #NAFLD @bmj_latest @FrontGastro_BMJ https://t.co/R08FHLbvTH
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Mashup Score: 5Non-alcoholic fatty liver disease and risk of new-onset heart failure: an updated meta-analysis of about 11 million individuals - 2 year(s) ago
Objective Recent studies reported an association between non-alcoholic fatty liver disease (NAFLD) and increased risk of new-onset heart failure (HF). However, the magnitude of the risk and whether this risk changes with severity of liver disease remains uncertain. We performed a meta-analysis of observational studies to quantify the magnitude of the association between NAFLD and risk of…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease #GUTInTheNews - read the paper by Mantovani et al on "Non-alcoholic fatty liver disease and risk of new onset heart failure: an updated meta-analysis of about 11 million individuals" via https://t.co/0hSJI0AfSO #LiverTwitter #NAFLD @bmj_latest @FrontGastro_BMJ https://t.co/ncyniLIgzy
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Mashup Score: 0
Background Recent evidence suggests a role for the microbiome in pancreatic ductal adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and salivary microbiota as potential diagnostic biomarkers. Methods We applied shotgun metagenomic and 16S rRNA amplicon sequencing to samples from a Spanish case–control study (n=136), including 57 cases, 50 controls, and 29…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease by @ps_ecekartal et al on "A faecal microbiota signature with high specificity for pancreatic cancer"- https://t.co/AaKZLMcOyX #Commentary - @newsome_rachel & Jobin- https://t.co/m7FAdvgp8M @TSBSchm @olex_maistrenko @ZellerGroup @JonelTrebicka @nmalats @BorkLab https://t.co/hVb7iYiWoI
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Mashup Score: 2
Background Recent evidence suggests a role for the microbiome in pancreatic ductal adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and salivary microbiota as potential diagnostic biomarkers. Methods We applied shotgun metagenomic and 16S rRNA amplicon sequencing to samples from a Spanish case–control study (n=136), including 57 cases, 50 controls, and 29…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease by @ps_ecekartal et al on "A faecal microbiota signature with high specificity for pancreatic cancer"- https://t.co/AaKZLMcOyX #Commentary - @newsome_rachel & Jobin- https://t.co/m7FAdvgp8M @TSBSchm @olex_maistrenko @ZellerGroup @JonelTrebicka @nmalats @BorkLab https://t.co/SwtW3xm0Ej
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Mashup Score: 0
Background Recent evidence suggests a role for the microbiome in pancreatic ductal adenocarcinoma (PDAC) aetiology and progression. Objective To explore the faecal and salivary microbiota as potential diagnostic biomarkers. Methods We applied shotgun metagenomic and 16S rRNA amplicon sequencing to samples from a Spanish case–control study (n=136), including 57 cases, 50 controls, and 29…
Source: GutCategories: Gastroenterology, Latest HeadlinesTweet-
#GUTPressRelease by @ps_ecekartal et al on "A faecal microbiota signature with high specificity for pancreatic cancer"- https://t.co/AaKZLMcOyX #Commentary - @newsome_rachel & Jobin- https://t.co/m7FAdvgp8M @TSBSchm @olex_maistrenko @ZellerGroup @JonelTrebicka @nmalats @BorkLab https://t.co/VtfwGlN7iH
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#GUTInTheNews #GUTPressRelease on the paper by Konings et al entitled "GI syndromes preceding a diagnosis of Parkinson’s disease: testing Braak’s hypothesis using a nationwide database for comparison with Alzheimer’s disease & cerebrovascular diseases" via https://t.co/idzXKiIsj4 https://t.co/12OJsIcjPR