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Mashup Score: 0Relapse Risk and Safety of Long-Term Tocilizumab Use Among Patients With Giant Cell Arteritis: A Single-Enterprise Cohort Study - 7 month(s) ago
Objective To evaluate the safety and efficacy of tocilizumab (TCZ) in giant cell arteritis (GCA) in a large North American cohort. Methods Patients with GCA treated with TCZ between January 1, 2010, and May 15, 2020, were retrospectively identified. Kaplan-Meier methods were used to estimate time to TCZ discontinuation and time to first relapse after TCZ discontinuation. Poisson regression models were used to compare annualized relapse rates before, during, and after TCZ use. Age- and sex-adjusted risk factors associated with relapse on and off TCZ and development of adverse events of significant interest (AESIs) were examined using Cox models. Results One hundred fourteen patients (60.5% female) were included with mean (SD) age 70.4 (8.2) years. Median duration from GCA diagnosis to TCZ start was 4.5 months. Median overall duration of TCZ treatment was 2.3 years. Relapse rate prior to TCZ start (0.84 relapses/person-year) was 3-fold reduced while on TCZ (0.28 relapses/person-year; P <
Source: www.jrheum.orgCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 3Evidence on treat to target strategies in polymyalgia rheumatica and giant cell arteritis: a systematic literature review - 7 month(s) ago
AbstractObjectives. To inform an international task force about current evidence on Treat to Target (T2T) strategies in PMR and GCA.Methods. A systematic litera
Source: academic.oup.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Exploring giant cell arteritis article collection - 11 month(s) ago
Discover the latest giant cell arteritis research from Rheumatology and Rheumatology Advances in Practice. This collection brings together the la
Source: Oxford AcademicCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 5Giant Cell Arteritis Podcasts - 11 month(s) ago
23 May 2023 We’re excited to present a series of engaging and informative giant cell arteritis podcasts that delve into various aspects of rheumatology. In this blog post, we will highlight three episodes that provide valuable insights and information from our Talking Rheumatology Cases, Spotlight, and Research podcasts. Podcast 1: “Non-GCA Headache”…
Source: www.rheumatology.org.ukCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Exploring giant cell arteritis article collection - 12 month(s) ago
Discover the latest giant cell arteritis research from Rheumatology and Rheumatology Advances in Practice. This collection brings together the la
Source: Oxford AcademicCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 1Giant cell arteritis | British Society for Rheumatology - 1 year(s) ago
This webinar delivers a curriculum-based update on what you need to know about Giant cell arteritis. The topic is designed for trainees but everyone is welcome to attend.
Source: www.rheumatology.org.ukCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Is PJP Prophylaxis Indicated in Patients With Giant Cell Arteritis or Polymyalgia Rheumatica? - 1 year(s) ago
Results of a recent study showed that the risk of pneumocystis jiroveci pneumonia (PJP) is low in patients with giant cell arteritis (GCA) and polymyalgia rheumatica (PMR), therefore discouraging the routine prescribing of PJP prophylaxis for this patient population.
Source: HCP LiveCategories: General Medicine News, Latest HeadlinesTweet
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Mashup Score: 0Is PJP Prophylaxis Indicated in Patients With Giant Cell Arteritis or Polymyalgia Rheumatica? - 1 year(s) ago
Results of a recent study showed that the risk of pneumocystis jiroveci pneumonia (PJP) is low in patients with giant cell arteritis (GCA) and polymyalgia rheumatica (PMR), therefore discouraging the routine prescribing of PJP prophylaxis for this patient population.
Source: HCP LiveCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 9Progressive Vertebrobasilar Vasculopathy and Stroke Secondary to Giant Cell Arteritis - 2 year(s) ago
Yasamin Mahjoub Correspondence to: Yasamin Mahjoub, MD, Foothills Medical Centre, 1403 29 St NW, Calgary, AB T2N 2T9. Email E-mail Address: [email protected] https://orcid.org/0000-0003-0898-3307 Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Alberta, Canada. Search for more papers by this author
Source: StrokeCategories: Cardiology News and Journals, Latest HeadlinesTweet
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Mashup Score: 2
Objective Aberrant Rho-associated protein kinase (ROCK) activity is implicated in several vascular and immunologic disorders. We previously demonstrated increased ROCK activity in histopathologically negative temporal artery biopsies (TABs) in subjects with clinical giant cell arteritis (GCA) compared to those without GCA. This current study aimed to examine ROCK activity in a larger cohort of…
Source: The Journal of RheumatologyCategories: Latest Headlines, RheumatologyTweet
Research Article Relapse Risk and Safety of Long-Term Tocilizumab Use Among Patients With Giant Cell Arteritis: A Single-Enterprise Cohort Study 📰 https://t.co/7N2dHPqL2N #giantcellarteritis #tocilizumab #treatment #vasculitis https://t.co/od0nRxB7lS