• Mashup Score: 1

    A fact sheet that summarizes the evidence linking alcohol consumption to the risk of various cancers. Includes information about factors that affect the risk of alcohol-associated cancers.

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    • #DYK: A person’s risk of alcohol-related cancers is influenced by their genes, specifically the genes that encode enzymes involved in metabolizing #alcohol? Read more on how #genetics affect the risk of alcohol-related cancers: https://t.co/MswTH4MNXt https://t.co/TkwEMLvcuJ

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    Currently, oncologists use genetic tests to help personalize care for certain patients with aggressive prostate cancer. The results of the tests can inform treatment—including with one class of tar geted therapies that has proved effective against some inherited prostate cancers—and encourage genetic screenings among the patients’ family members so that they have the chance to reduce their cancer risk and work with physicians to be more vigilant in early detection. In the new study, the researchers

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    • Genetic Mutations in Aggressive Prostate Cancer https://t.co/hLpRfBQo4O #pcsm #prostatecancer #genetics #oncology

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    In a study reported in the Journal of Clinical Oncology, Mandelker et al found that pancreatic acinar cell carcinoma was associated with a high prevalence of BRCA2 germline pathogenic variants and genomic features of homologous recombination deficiency (HRD). The study involved somatic and germline analyses in a clinical cohort of 28,780 patients with cancer at Memorial Sloan Kettering Cancer Center, of whom 49 were diagnosed with pancreatic acinar cell carcinoma. Whole-genome sequencing was performed in

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    • Germline Predisposition and Homologous Recombination Deficiency in Pancreatic Acinar Cell Carcinoma https://t.co/THoJ1twgLy #pancsm #PancreaticCancer #oncology #Genetics

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    23andMe has announced that the company has received a U.S. Food and Drug Administration (FDA) 510(k) clearance to expand its existing BRCA1/BRCA2 (Selected Variants) Genetic Health Risk Report. The clearance allows 23andMe to report an additional 41 variants in the BRCA1 and BRCA2 genes known to be associated with a higher risk of developing breast, ovarian, prostate, and pancreatic cancers. Many of the BRCA variants added through this most recent clearance are known to have a higher rate of occurrence

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    • 23andMe Granted @US_FDA 510(k) Clearance to Report Additional BRCA Variants https://t.co/GgMpo1V0fs @FDAOncology @23andMe #genetics #cancer

  • Mashup Score: 38

    Editorial from The New England Journal of Medicine — Hemostasis — A Balancing Act

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    • RT @NEJM: A balance between procoagulants and anticoagulants underpins hemostasis. Science behind the Study: https://t.co/NUqB2HCsEi 1/10…

    • Read the science behind the study in a new editorial, “Hemostasis — A Balancing Act” by H. Marijke van den Berg, M.D., Ph.D., and Alok Srivastava, M.D.”: https://t.co/NUqB2HCsEi 10/10 #pediatrics #genetics