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Mashup Score: 45
Don’t miss what’s happeningPeople on X are the first to know.Log inSign upSettingsPostCristina Popa @NephroSeeker@med-mastodon.com@NephroSeeker1/@hswapnil starting @RoySocMed talk, declaring his COIs Well, as we saw in #KidneyWk LBCT session, being part of the #NephJC board is a big COI, but having no financial COI makes him (Nephjc) talk freely8:06 PM · Nov 29, 20236,875 Views6 Reposts1 Quote12…
Source: x.comCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 3Woman With Diplopia - 5 month(s) ago
A 37-year-old woman with a history of chronic alcohol use presented to the emergency department with a 1-day history of diplopia. Her vital signs were a blood pressure of 120/64 mmHg, pulse rate of 96 beats/min, and temperature of 36.8 °C. Physical examination was remarkable for bilateral lateral rectus muscle palsy with disconjugate gaze (Figures 1 and 2; Video 1). Laboratory results and computed tomography of the head were unremarkable.
Source: www.annemergmed.comCategories: General Medicine News, Critical CareTweet
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Mashup Score: 5Can epinephrine be used as an inotrope? - 5 month(s) ago
Are you using epinephrine like this?Did you know that at lower doses, epinephrine can be used as an inotrope, not just a vasopressor. Epinephrine has both al…
Source: www.youtube.comCategories: General Medicine News, Critical CareTweet
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Mashup Score: 22How End-Tidal CO2 is more than just hot air. - 6 month(s) ago
In this video from ResusX:ReVolved (see link below), Dr. Max Hockstein, an Emergency Physician and Intensivist, introduces the concept of “End-Tidal Capnogra…
Source: www.youtube.comCategories: General Medicine News, Critical CareTweet
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Mashup Score: 6Infant Vomiting, Orbital Cellulitis, TXA in Trauma, Delirium, Procedural Skills Decay, Altitude Sickness | EM Quick Hits | EM Cases - 6 month(s) ago
Infant Vomiting, Orbital Cellulitis, Prehospital TXA in Trauma, Prevention and Treatment of Delirium, Procedural Skills Decay, Altitude Sickness on this EM Cases Quick Hits podcast
Source: emergencymedicinecases.comCategories: General Medicine News, General HCPsTweet-
Dr. Sarah Reid (@sallyann5679) shares an approach to infant vomiting in our latest EM Quick Hits episode: https://t.co/PGGg3qrUkY 👶🏽Sick or not sick? 🌡️Febrile or afebrile? 🤮Bilious Emesis? 👇🏽Check out the structural diseases table below #FOAMed @long_brit @clshenvi @first10em https://t.co/SiEdLFvu2a
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Mashup Score: 6Infant Vomiting, Orbital Cellulitis, TXA in Trauma, Delirium, Procedural Skills Decay, Altitude Sickness | EM Quick Hits | EM Cases - 7 month(s) ago
Infant Vomiting, Orbital Cellulitis, Prehospital TXA in Trauma, Prevention and Treatment of Delirium, Procedural Skills Decay, Altitude Sickness on this EM Cases Quick Hits podcast
Source: emergencymedicinecases.comCategories: General Medicine News, General HCPsTweet-
Dr. Sarah Reid (@sallyann5679) shares an approach to infant vomiting in our latest EM Quick Hits episode: https://t.co/PGGg3qrUkY 👶🏽Sick or not sick? 🌡️Febrile or afebrile? 🤮Bilious Emesis? 👇🏽Check out the structural diseases table below #FOAMed @long_brit @clshenvi @first10em https://t.co/SiEdLFvu2a
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Mashup Score: 0Therapeutic S100A8/A9 blockade inhibits myocardial and systemic inflammation and mitigates sepsis-induced myocardial dysfunction - Critical Care - 7 month(s) ago
Background and Aims The triggering factors of sepsis-induced myocardial dysfunction (SIMD) are poorly understood and are not addressed by current treatments. S100A8/A9 is a pro-inflammatory alarmin abundantly secreted by activated neutrophils during infection and inflammation. We investigated the efficacy of S100A8/A9 blockade as a potential new treatment in SIMD. Methods The relationship between plasma S100A8/A9 and cardiac dysfunction was assessed in a cohort of 62 patients with severe sepsis admitted to the intensive care unit of Linköping University Hospital, Sweden. We used S100A8/A9 blockade with the small-molecule inhibitor ABR-238901 and S100A9−/− mice for therapeutic and mechanistic studies on endotoxemia-induced cardiac dysfunction in mice. Results In sepsis patients, elevated plasma S100A8/A9 was associated with left-ventricular (LV) systolic dysfunction and increased SOFA score. In wild-type mice, 5 mg/kg of bacterial lipopolysaccharide (LPS) induced rapid plasma S100A8/A9
Source: ccforum.biomedcentral.comCategories: Critical Care, Latest HeadlinesTweet
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Mashup Score: 1Cannon A Waves | NEJM - 7 month(s) ago
Images in Clinical Medicine from The New England Journal of Medicine — Cannon A Waves
Source: www.nejm.orgCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Prophylactic platelet transfusion response in critically ill patients: a prospective multicentre observational study - Critical Care - 7 month(s) ago
Background Response to prophylactic platelet transfusion is suspected to be inconsistent in critically ill patients questioning how to optimize transfusion practices. This study aimed to describe prophylactic platelet transfusion response, to identify factors associated with a suboptimal response, to analyse the correlation between corrected count increment and platelet count increment and to determine the association between poor platelet transfusion response and clinical outcomes. Methods This prospective multicentre observational study recruited patients who received at least one prophylactic platelet transfusion in one of the nine participating intensive care units for a period up to 16 months. Poor platelet transfusion response was defined as a corrected count increment (CCI) that adjusts for platelet dose and body surface area, less than 7 at 18–24 h after platelet transfusion. Factors associated with poor platelet transfusion response were assessed in a mixed-effect model. Sensi
Source: ccforum.biomedcentral.comCategories: Critical Care, Latest HeadlinesTweet
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Mashup Score: 2Immunosuppressive effects of circulating bile acids in human endotoxemia and septic shock: patients with liver failure are at risk - Critical Care - 7 month(s) ago
Background Sepsis-induced immunosuppression is a frequent cause of opportunistic infections and death in critically ill patients. A better understanding of the underlying mechanisms is needed to develop targeted therapies. Circulating bile acids with immunosuppressive effects were recently identified in critically ill patients. These bile acids activate the monocyte G-protein coupled receptor TGR5, thereby inducing profound innate immune dysfunction. Whether these mechanisms contribute to immunosuppression and disease severity in sepsis is unknown. The aim of this study was to determine if immunosuppressive bile acids are present in endotoxemia and septic shock and, if so, which patients are particularly at risk. Methods To induce experimental endotoxemia in humans, ten healthy volunteers received 2 ng/kg E. coli lipopolysaccharide (LPS). Circulating bile acids were profiled before and after LPS administration. Furthermore, 48 patients with early (shock onset within < 24 h) and severe
Source: ccforum.biomedcentral.comCategories: Critical Care, Latest HeadlinesTweet
I am preparing a 2023 Update in Nephrology lecture. What would you add to this Slide? Yes, I am borrowing from @hswapnil recent lecture, that's the point of #FOAMed https://t.co/oQalqRG2XP https://t.co/IkEnvfqZpj https://t.co/OCLp49uDNA