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    Author summary Vascular Ehlers-Danlos syndrome (vEDS) is a rare vascular genetic disease leading to life-threatening arterial and colonic fragility in young adulthood. We created a new mutant mouse with a typical disease-causing variant in the gene responsible for vEDS. This mouse recapitulates the vEDS vascular features with spontaneous mortality due to aortic rupture. We also tested several…

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    • New research on #EhlersDanlos syndrome: Legrand et al use a new knock-in #mouse model to test antihypertensive therapeutic strategies, finding one improves survival #genetics #RareDisease https://t.co/4pXCBs3XZA

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    Author summary Vascular Ehlers-Danlos syndrome (vEDS) is a rare vascular genetic disease leading to life-threatening arterial and colonic fragility in young adulthood. We created a new mutant mouse with a typical disease-causing variant in the gene responsible for vEDS. This mouse recapitulates the vEDS vascular features with spontaneous mortality due to aortic rupture. We also tested several…

    Tweet Tweets with this article
    • New research on #EhlersDanlos syndrome: Legrand et al use a new knock-in #mouse model to test antihypertensive therapeutic strategies, finding one improves survival @Inserm @HopitalPompidou #genetics https://t.co/4pXCBs3XZA

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    Our second flagship journal of 2021 comprises a selection of articles highlighting key advances across a range of therapeutic disciplines…

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    • We are proud to present our latest flagship journal. Discover our latest peer-reviewed, open-access articles on topics including rheumatology, and more. Read it today! https://t.co/vF4bCVcPxj #rheumatology #ehlersdanlos #stretchyskin #fragileskin #jointhypermobility https://t.co/BEgrGkMq60

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    The Ehlers-Danlos syndromes (EDS) are a group of hereditary disorders of connective tissue that are varied in the ways they affect the body and in their genetic causes. The underlying concern is the abnormal structure or function of collagen and certain allied connective tissue proteins.  They are generally characterized by joint hypermobility (joints that move further than normal range), joint…

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    • The #EhlersDanlos syndromes (#EDS) are a group of connective tissue disorders, and patients often suffer from joint pain. Access to proper #PainManagement is key to preserving quality of life. Learn more from @TheEDSociety: https://t.co/w5DebxgHU6 #ChronicPain #pain

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    Chronic pain is a leading cause of disability globally and associated with enormous health-care costs. The discrepancy between the extent of tissue damage and the magnitude of pain, disability, and associated symptoms represents a diagnostic challenge for rheumatology specialists. Central sensitisation, defined as an amplification of neural signalling within the CNS that elicits pain…

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    • REVIEW: Central sensitization in #chronicpain conditions: latest discoveries and their potential for #precisionmedicine. @TheLancet https://t.co/u52bo9Qwq3 #PM101 #PAIN #Rheumatology #fibromyalgia #osteoarthritis #rheumatoidarthritis #EhlersDanlos #CFS #MECFS #hyperalgesia https://t.co/ZdzR2aqMdo

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    Nancy W. Burkhart, EdD, MEd, BSDH, AAFAAOM, and Carol Perkins, BA, AS, RDH, review the clinical signs of Ehlers-Danlos syndrome, an inherited connective tissue disorder, and suggest ways to make dental appointments for EDS patients go more smoothly.

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    • Nancy W. Burkhart and Carol Perkins review the clinical signs of Ehlers-Danlos syndrome, an inherited connective tissue disorder, and suggest ways to make #dental appointments for EDS patients go more smoothly. https://t.co/uKccB24dGF #EhlersDanlos #dentistry

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    Professor Howard Bird - 3 year(s) ago

    Help Ai Lyn Tan raise money to support Pancreatic Cancer UK

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    • Professor Howard Bird did so much for #rheumatology #hypermobility #EhlersDanlos #music @RheumatologyUK @VersusArthritis @HMSACharity @ehlersdanlosuk @PerfArtsMedUCL @UniversityLeeds @UniLeedsStaff @LeedsHospitals @LeedsBRC In his memory @PancreaticCanUK https://t.co/IdzG3ONIyW