• Mashup Score: 1

    CARB-X to fund development of CRISPR-based drug for E coli infectionsCARB-X announced today that it is awarding up to $3.9 million to a Danish microbiome biotechnology company to develop a CRISPR-based drug to prevent Escherichia coli infections in cancer patients.The award will help Copenhagen-based SNIPR BIOME ApS develop its lead drug candidate, SNIPR001, which uses…

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    • STEWARDSHIP / RESISTANCE SCAN: CRISPR-based drug for #Ecoli; WHO stewardship guidance; Inadequate antibiotic therapy #AMR #AntibioticStewardship @CARB_X https://t.co/Mc04wYp2a5

  • Mashup Score: 1

    Researchers at Monash University in Australia have developed a technique to create 3D engineered surfaces that reduce bacterial growth. Their approach could lead to frequently touched surfaces in healthcare facilities that result in less bacterial transmission. This should lead to a reduction in the incidence of hospital acquired infections, such as urinary tract infections in patients with…

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    • Researchers have developed a technique to create 3D engineered surfaces that reduce bacterial growth on frequently touched surfaces in healthcare facilities via @Medgadget https://t.co/EVydSYrZ0J #Ecoli #microcolonies #antimicrobial #krystalklear #pulmonaryapps https://t.co/jbaHsiRtPE

  • Mashup Score: 23

    Shiga toxin is a phage-encoded exotoxin that interrupts protein translation and functions as a virulence factor for enterohemorrhagic Escherichia coli (EHEC), a human pathogen causing hemorrhagic colitis and acute renal failure. Havira et al. screened a panel of EHEC mutants lacking various virulence factors for mutants that interfered with inflammasome-mediated cell death. EHEC strains lacking…

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    • A new @SciImmunology study from reveals that Shiga toxins, produced by certain strains of #Ecoli, can be more than toxic, capable of subverting #immune responses in the body to help bacteria thrive in the animal host: https://t.co/d2mGvoVWq9 https://t.co/9RgewosO0i

  • Mashup Score: 30

    Shiga toxin is a phage-encoded exotoxin that interrupts protein translation and functions as a virulence factor for enterohemorrhagic Escherichia coli (EHEC), a human pathogen causing hemorrhagic colitis and acute renal failure. Havira et al. screened a panel of EHEC mutants lacking various virulence factors for mutants that interfered with inflammasome-mediated cell death. EHEC strains lacking…

    Tweet Tweets with this article
    • A new @SciImmunology study from reveals that Shiga toxins, produced by certain strains of #Ecoli, can be more than toxic, capable of subverting #immune responses in the body to help bacteria thrive in the animal host: https://t.co/d2mGvoVWq9 https://t.co/7gxAe18nQ9

  • Mashup Score: 7

    Shiga toxin is a phage-encoded exotoxin that interrupts protein translation and functions as a virulence factor for enterohemorrhagic Escherichia coli (EHEC), a human pathogen causing hemorrhagic colitis and acute renal failure. Havira et al. screened a panel of EHEC mutants lacking various virulence factors for mutants that interfered with inflammasome-mediated cell death. EHEC strains lacking…

    Tweet Tweets with this article
    • A new study from @KailasanVanaja and @uconnhealth reveals that Shiga toxins, produced by certain strains of #Ecoli, can be more than toxic, capable of subverting #immune responses in the body to help bacteria thrive in the animal host: https://t.co/Nsm4i8A22I https://t.co/Ct0TdhI83k