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    The hypothesis that dabigatran would provide sufficient anticoagulation for cardiopulmonary bypass was tested in a first-use, proof-of-concept study using a rabbit model of cardiopulmonary bypass that included a comparison group receiving heparin. The dabigatran loading dose and maintenance infusions were designed after first determining its pharmacokinetics in rabbits and the target…

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    • In a first-use, proof-of-concept study, researchers using a rabbit CPB model showed that #dabigatran provides acceptable #anticoagulation similar to heparin to prevent thrombosis. Read the new article published in @_Anesthesiology: https://t.co/iFCyHjygqM https://t.co/vsIotk2Jc2

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    In the GIRAF trial, older adults with atrial fibrillation or atrial flutter who were treated with dabigatran or warfarin had similar cognitive outcomes at 2 years, researchers reported at the American Heart Association Scientific Sessions.“Previous studies demonstrated that anticoagulation is good for the prevention of stroke, but cognitive outcomes were somehow neglected. I consider

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    • In the GIRAF trial, older adults with #AFib or atrial flutter who were treated with #dabigatran or #warfarin had similar cognitive outcomes at 2 years @usponline @AHAMeetings #AHA21 #CardioTwitter https://t.co/TvfNrEjRxi