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Mashup Score: 7Researcher discusses turbocharging CRISPR to understand how the immune system fights cancer - 2 month(s) ago
Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer. As researchers have learned more and more about the cancer-immune system interplay, several …
Source: medicalxpress.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 498A versatile CRISPR-Cas13d platform for multiplexed transcriptomic regulation and metabolic engineering in primary human T cells - 2 month(s) ago
MEGA is a programmable RNA-targeting platform that enables safe and effective multiplexed genetic perturbation of the primary human T cell transcriptome. Multi-gene disruption broadly enhances the anti-tumor activity of CAR T cells and uncovers a role for aerobic glycolysis in driving T cell exhaustion.
Source: www.cell.comCategories: General Medicine News, Expert PicksTweet
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Mashup Score: 50A new RNA editing tool could enhance cancer treatment - 2 month(s) ago
Cell therapies for cancer can be potentially enhanced using a CRISPR RNA-editing platform, according to a new study published Feb. 21 in Cell.
Source: phys.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 43Junk DNA in birds may hold key to safe, efficient gene therapy - 2 month(s) ago
For many genetic diseases, disabling or editing a gene using CRISPR is insufficient to overcome the effects of the underlying genetic mutation. A corrective gene needs to be added to the genome to fix the problem. Researchers have discovered a way to use a bird retrotransposon — a type of junk DNA — to insert whole transgenes into the human genome in a targeted way that does not risk damaging other genes.
Source: www.sciencedaily.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 1Gene-editing breakthrough for a rare hereditary disorder - 3 month(s) ago
Nature Medicine – Patients who received an in vivo CRISPR-based gene-editing therapy for hereditary angioedema showed no serious side effects and nearly complete disease control.
Source: www.nature.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 15CRISPR gene editing gets a revolutionary upgrade with new tool - 3 month(s) ago
In the realm of scientific innovation, the past decade has seen the CRISPR/Cas systems emerge as a groundbreaking tool in genome editing.
Source: www.earth.comCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 114New CRISPR tool accelerates and optimizes genome editing - 3 month(s) ago
CRISPR/Cas systems have undergone tremendous advancement in the past decade. These precise genome editing tools have applications ranging from transgenic crop development to gene therapy and beyond. And …
Source: phys.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 3Targeted CRISPR In Vivo Delivery System Shows Promise - 3 month(s) ago
This technique allows for gene editing on specific subsets of cells while they are still in the body, which is a major step toward a programmable delivery method that would eliminate the need for destroying a patients’ bone marrow and immune system.
Source: www.laboratoryequipment.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Targeted CRISPR In Vivo Delivery System Shows Promise - 3 month(s) ago
This technique allows for gene editing on specific subsets of cells while they are still in the body, which is a major step toward a programmable delivery method that would eliminate the need for destroying a patients’ bone marrow and immune system.
Source: www.laboratoryequipment.comCategories: General Medicine News, General HCPsTweet
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Mashup Score: 47CRISPR engineered viruses could render other viruses harmless - 3 month(s) ago
A virus engineered using CRISPR technology spread its DNA to other viruses in mice, which could be used to make viral pathogens harmless
Source: www.newscientist.comCategories: General Medicine News, Future of MedicineTweet
Researcher discusses turbocharging #CRISPR to understand how the immune system fights cancer @harvardmed @natimmunol @JExpMed https://t.co/LbDPeTGTrt