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    While the locations and causes of multiple cranial neuropathy are highly diverse, the fact that tumor composes more than one quarter of cases places a premium on prompt diagnosis.

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    • In this review of 979 (!) cases https://t.co/XXAEOdixLz The most common causes of multiple CNs (in decreasing order of frequency) -Tumor (schwannoma, mets, meningiomas) -Brainstem stroke -Trauma -Infection (meningitis (bacterial and fungal), botulism, mucor, syphilis) -GBS

    • In this review of 979 (!) cases https://t.co/XXAEOdixLz Most common CNs affected: - šŸ‘ļø6 (due to many cavernous sinus cases) - šŸ«¤ 7(most commonly in GBS) - 5 and 3 (also 2/2 cav sinus)

    • In this review of 979 (!) cases https://t.co/XXAEOdixLz *Avg #CNs affected per pt=2.7 (1 pt had all 12 affected unilaterally (nasopharyngeal CA)!) *Of 50 pts w >/= 8 CNs involved ~1/2=GBS! (others=tumor, botulism) * Most common localizations cavernous sinus & brainstem

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    Two experts discuss the potential role of using adagrasib and sotorasib in the front-line setting and how it might shift the treatment paradigm for patients with KRASG12C-mutated NSCLC with CNS metastases.

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    • Two experts discuss the potential role of using #adagrasib and #sotorasib in the front-line setting and how it might shift the treatment paradigm for patients with KRASG12C-mutated #NSCLC with #CNS metastases. #lcsm | @JSabari @AdventHealth @nyulangone https://t.co/hqf7GPQS9b

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    Anatomical, cellular and molecular immuneĀ interactions at the borders of the centralĀ nervous system control homeostatic brain function andĀ can lead to neurological or psychiatric diseases, representing potential therapeutic targets.

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    • REVIEW: #Brain borders at the central stage of #neuroimmunology. @Nature https://t.co/LdSVB3izR9 "#meninges are now recognized as active participants in diverse brain functions .. contain numerous innate and adaptive populations capable of producing diverse #cytokines" #CNS https://t.co/X4TgNd4D3n