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    Melanoma patients who had vax plus PD-1 inhibitor did better than those on pembrolizumab alone

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    • An investigational mRNA #cancervaccine met its primary endpoint in a phase IIb study, @moderna_tx and @Merck announced Tuesday. Moderna CEO Stéphane Bancel called the results "highly encouraging for the field of cancer treatment." https://t.co/FE36mwhZ7h @KristinaMFiore

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    It uses the same messenger-RNA technology as some Covid-19 vaccines.

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    • Another good news today! A pivotal trial of a personalized #cancervaccine that uses the same messenger-RNA technology as COVID jabs was just completed! @moderna_tx and @Merck are behind it, and they called the results "a new paradigm" moment. https://t.co/Vv6JALD3vj

  • Mashup Score: 17

    Novel design stimulates a coordinated attack by T and natural killer cells that prevents metastasis in mice

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    • A new type of #CancerVaccine tested in mice greatly reduced metastasis & was active against tumor cells resistant to other immunotherapies. The vaccine works by taking away a defense strategy of the tumor and producing an immune cell attack. https://t.co/A8e6SIUAfs @theNCI #NIH

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    Immunotherapy has been a milestone in combatting cancer, by complementing or even replacing classic treatments like surgery, chemotherapy, radiation, and anti-hormonal therapy. In 15%-30% of breast cancers, overexpression of the human epidermal growth factor receptor 2 (Her-2/neu) is associated with more aggressive tumor development. Passive immunization/immunotherapy with the recombinantly…

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    • Check out the newest @ESMO_Open review: Vaccination against Her-2/neu, with focus on peptide-based vaccines #cancervaccine @cczielinski @myESMO #OncoAlert https://t.co/9MpFKQ64zJ https://t.co/NhGMCfX7EZ