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Mashup Score: 0Leisure-Time Physical Activity and Risk of 26 Types of Cancer - 3 month(s) ago
This study of pooled data from 12 US and European cohorts examines the association of leisure-time physical activity with incidence of 26 common types of cancer and whether the associations vary by body size and/or smoking.
Source: jamanetwork.comCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 3#cametab - Healthcare Social Media Analytics and Transcripts - 4 month(s) ago
This action requires you to be signed into your Symplur Account. It’s free to
Source: www.symplur.comCategories: General Medicine News, Hem/OncsTweet-
Top Influencers of Cancer Metabolomics #cametab 👉 @JCO_ASCO @benjiwal https://t.co/qmr4elLua2 via @symplur
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Mashup Score: 9Advancing CAR T cell therapy through the use of multidimensional omics data - Nature Reviews Clinical Oncology - 1 year(s) ago
Data obtained using omics technologies can offer important insights into various aspects of chimeric antigen receptor (CAR) T cell therapy. In this Review, the authors provide an overview of the multidimensional profiling technologies that have been applied in investigations of CAR T cell therapy. They then discuss the ways in which multi-omics data obtained through such analyses can be used to…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
In a new Review now live online, Michael Green, Leng Han and co-author discuss the opportunities to advance CAR T cell therapy through the use of multidimensional omics data, as well as the associated challenges: https://t.co/IZhSqo75uM #ImmunoOnc #cagenome #cametab #caproteo https://t.co/gQ0H6Si8ZP
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Mashup Score: 0Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors - Nature Cancer - 2 year(s) ago
Winter and colleagues demonstrate that metabolic adaptation to nutrient stress in the tumor microenvironment of pancreatic cancer leads to a dependency on IDH1, which is therapeutically actionable regardless of IDH1 mutation status.
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Study in mouse models shows that metabolic changes owing to limited nutrient availability in the TME renders IDH-wild-type pancreatic tumours sensitive to allosteric IDH1 inhibitors: https://t.co/Ae0Ph1VmGX. Also see: https://t.co/iCBdFkz4Fa #PancSM #camicroenv #cametab
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Mashup Score: 0Mutant IDH Inhibits IFNγ–TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma - 2 year(s) ago
The efficacy of mutant IDH1 inhibition in a genetically engineered mouse model of cholangiocarcinoma is mediated by stimulation of cytotoxic T-cell function and derepression of TET2 in tumor cells, which epigenetically resensitizes tumor cells to IFNγ.
Categories: Hem/Oncs, Latest HeadlinesTweet-
Mutant IDH Inhibits IFNγ–TET2 Signaling to Promote Immunoevasion and Tumor Maintenance in Cholangiocarcinoma [Mar 8, 2022] @itsacurse et al. @BCD_AACR https://t.co/QFtLZn085q #PrecisionMedicine #ImmunoOnc #hpbcsm #cametab
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Mashup Score: 1
Blood Cancer Journal – Body mass index and risk of progression from monoclonal gammopathy of undetermined significance to multiple myeloma: Results from the Prostate, Lung, Colorectal and Ovarian…
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
Body mass index and risk of progression from monoclonal gammopathy of undetermined significance to multiple myeloma: Results from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial [Apr 1, 2022] Chang et al. @BloodCancerJnl https://t.co/2LTTIlNqKx #mmsm #cametab
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Mashup Score: 1
Blood Cancer Journal – Body mass index and risk of progression from monoclonal gammopathy of undetermined significance to multiple myeloma: Results from the Prostate, Lung, Colorectal and Ovarian…
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
Body mass index and risk of progression from monoclonal gammopathy of undetermined significance to multiple myeloma: Results from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial [Apr 1, 2022] Chang et al. @BloodCancerJnl https://t.co/2LTTIlNqKx #mmsm #cametab https://t.co/SHkSVngGmt
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Mashup Score: 1The Multiple Myeloma Daily - 2 year(s) ago
A selection of articles, blog posts, videos and photos recommended by Robert Z. Orlowski
Source: paper.liCategories: Hem/Oncs, Latest HeadlinesTweet-
The latest The Multiple Myeloma Daily! https://t.co/5c3lKvc3Li Thanks to @mtmdphd @VJHemOnc #mmsm #cametab
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Mashup Score: 0
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant clonal disorder that progresses to multiple myeloma (MM), or other plasma-cell or lymphoid disorders at a rate of 1%/year. We evaluate the contribution of body mass index (BMI) to MGUS progression beyond established clinical factors in a population-based study. We identified 594 MGUS through a population-based screening…
Source: NatureCategories: Hem/Oncs, Latest HeadlinesTweet-
Body mass index associated [BMI] with monoclonal gammopathy of undetermined significance (MGUS) progression in Olmsted County, Minnesota [Apr 19, 2022] Geffen Kleinstern et al. @MayoMyeloma @BloodCancerJnl https://t.co/2g4Px4d3O4 #mmsm #cametab #openaccess n=594 MGUS https://t.co/MMauHBJj5p
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Mashup Score: 0The Association between Metabolic Syndrome and Multiple Myeloma - 2 year(s) ago
Multiple myeloma (MM) is a haematological malignancy arising from monoclonal proliferation of plasma cells in the bone marrow, resulting in the presence of paraproteins or M-protein in serum. The involvement of paraproteins produced by malignant plasma cells in the development of hyperlipidaemia and low-HDL cholesterol has been described, as has an
Source: www.karger.comCategories: Hem/Oncs, Latest HeadlinesTweet-
The Association between Metabolic Syndrome and Multiple Myeloma [May 14, 2020] Ragbourne et al. Acta Haematologica https://t.co/hgRx8TjomB #mmsm #cametab
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Leisure-Time Physical Activity Assoc w/ 26 Cancers in 1.44M Adults [6/2016] Moore et al. @JAMAInternalMed https://t.co/v6H53QBFN6 #cametab