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Mashup Score: 0Whole-genome sequencing of multiple myeloma reveals oncogenic pathways are targeted somatically through multiple mechanisms - 7 month(s) ago
Leukemia – Whole-genome sequencing of multiple myeloma reveals oncogenic pathways are targeted somatically through multiple mechanisms
Source: www.nature.comCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 0Paper: Whole-Exome Sequencing Identifies a Somatic Cell Mutation Signature That Predicts Relapse Risk and Survival Probability in Multiple Myeloma - 7 month(s) ago
Program: Oral and Poster Abstracts Session: 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Poster I Hematology Disease Topics & Pathways: multiple myeloma, Diseases, Technology and Procedures, Plasma Cell Disorders, Lymphoid Malignancies, Clinically relevant, genetic profiling 1 Adult Hematologic Malignancies & Stem Cell Transplant Section, University Hospitals Seidman Cancer Center, Shaker Hts, OH 2 Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 3 Institute
Source: ash.confex.comCategories: Hem/Oncs, Latest HeadlinesTweet-
Whole-Exome Sequencing Identifies a Somatic Cell Mutation Signature That Predicts Relapse Risk and Survival Probability in Multiple Myeloma [Dec 5, 2020] @EhsanMalekMD et al. #ASH21 Abstract 1355 https://t.co/lMZfsfMWCr #mmsm #cagenome https://t.co/Mg2dMF6laJ
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Mashup Score: 0Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: Genomics Is the Diagnosis - 7 month(s) ago
Advances in the genomic era have led to identification of cancer-causing genes and unprecedented progress in the development of gene-targeted therapies and agents that can unleash the immune system. These advances have improved the outlook for patients with lethal malignancies. Cancer is a genomic disease in that gene alterations drive the cellular growth and immune surveillance perturbations that enable malignant cells to take hold and to metastasize. Hereditary genetic factors play a key role in cancer
Source: ascopubs.orgCategories: Hem/Oncs, Latest HeadlinesTweet-
Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: Genomics Is the Diagnosis [Mar 17, 2023] @VivekSubbiah @Dr_R_Kurzrock @JCO_ASCO https://t.co/Os4PdAxBvW #PrecisionMedicine #cagenome #GeneticCounselors
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Mashup Score: 0Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: Genomics Is the Diagnosis - 8 month(s) ago
Advances in the genomic era have led to identification of cancer-causing genes and unprecedented progress in the development of gene-targeted therapies and agents that can unleash the immune system. These advances have improved the outlook for patients with lethal malignancies. Cancer is a genomic disease in that gene alterations drive the cellular growth and immune surveillance perturbations that enable malignant cells to take hold and to metastasize. Hereditary genetic factors play a key role in cancer
Source: ascopubs.orgCategories: Hem/Oncs, Latest HeadlinesTweet-
Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: Genomics Is the Diagnosis [Mar 17, 2023] @VivekSubbiah @Dr_R_Kurzrock @JCO_ASCO https://t.co/Os4PdAxBvW #PrecisionMedicine #cagenome #GeneticCounselors
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Mashup Score: 0Study Shows Germline Testing May Be Warranted for All Patients With Lung Cancer - The ASCO Post - 1 year(s) ago
By Chase Doyle Posted: 8/17/2022 4:03:00 PM Last Updated: 8/17/2022 3:18:49 PM Germline testing may be warranted for all patients with lung cancer, according to research presented by Sorscher et al during the August ASCO Plenary Series Program (Abstract 388570). The retrospective review of nearly 8,000…
Source: ascopost.comCategories: Hem/Oncs, Latest HeadlinesTweet-
Study Shows Germline Testing May Be Warranted for All Patients With Lung Cancer [Aug 17, 2022] by Chase Doyle @ASCOPost https://t.co/EeosDU7VV8 #lcsm #geneticcounselors #cagenome
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Mashup Score: 0Program Guide – ASCO Meeting Program Guide - 1 year(s) ago
AuthorsSteven SorscherWake Forest School of Medicine, Winston-Salem, NCSteven Sorscher, Jaclyn LoPiccolo, Elaine Chen, Brandie Heald, Scott T. Michalski, Sarah M. Nielsen, Robert Luke Nussbaum, Renato G. Martins, Edward D. EsplinOrganizationsWake Forest School of Medicine, Winston-Salem, NC, Dana–Farber Cancer Institute, Boston, MA, Invitae, San Francisco, CA, University of Washington, Seattle,…
Source: meetings.asco.orgCategories: Hem/Oncs, Latest HeadlinesTweet-
Landscape of pathogenic germline variants in Pts w/ lung cancer [Aug 16, 2022] Sorscher et al. #ASCOPlenarySeries @JCO_ASCO Abst 388570 https://t.co/DDbhHlr6Gs #lcsm #geneticcounselors #cagenome "all patients with lung cancer also be considered for germline genetic testing" https://t.co/2zhWCJlTKU
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Mashup Score: 0Current Social Media Conversations about Genetics and Genomics in Health: A Twitter-Based Analysis - PubMed - 1 year(s) ago
This content analysis provides insight about the types of conversation related to genomics and health. Conversations about genomics are occurring on Twitter, and they frequently emphasize rare genetic diseases and genetic disorders. These discussions tend to be driven by key influencers who primaril …
Source: PubMedCategories: Hem/Oncs, Latest HeadlinesTweet-
Current Social Media Conversations about Genetics and Genomics in Health: A Twitter-Based Analysis [Nov, 2018] Allen et al. Public Health Genomics https://t.co/30k52IfxlW #geneticcounselors #PrecisionMedicine #cagenome
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Mashup Score: 0Functional precision oncology using patient-derived assays: bridging genotype and phenotype - Nature Reviews Clinical Oncology - 1 year(s) ago
Genomics-based precision medicine has improved the outcomes of patients with certain types of cancers, although most do not derive benefit. Here, the authors describe the development of functional patient-specific assays, including those based on organoids, spheroids and explants, and how clinical implementation of these models might extend the benefits of precision medicine to a much broader…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
In a new Review, @AllardvanR, @jorisvandehaar & Emile Voest discuss the use of patient-derived tumour organoids, spheroids and explants in functional precision oncology assays to bridge genotypes and phenotypes: https://t.co/b9PDKeWAuG #camicroenv #cagenome https://t.co/B9DzwduAqQ
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Mashup Score: 0mRNA-seq whole transcriptome profiling of fresh frozen versus archived fixed tissues - BMC Genomics - 1 year(s) ago
Background The main bottleneck for genomic studies of tumors is the limited availability of fresh frozen (FF) samples collected from patients, coupled with comprehensive long-term clinical follow-up. This shortage could be alleviated by using existing large archives of routinely obtained and stored Formalin-Fixed Paraffin-Embedded (FFPE) tissues. However, since these samples are partially…
Source: BioMed CentralCategories: Hem/Oncs, Latest HeadlinesTweet-
mRNA-seq whole transcriptome profiling of fresh frozen versus archived fixed tissues [May 30, 2018] @noabossel et al. BMC Genomics @BioMedCentral https://t.co/V99PtiMGz5 #cagenome
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Mashup Score: 1
Oral and Poster Abstracts 651. Myeloma: Biology and Pathophysiology, excluding Therapy: Poster I multiple myeloma, Diseases, Technology and Procedures, Plasma Cell Disorders, Lymphoid Malignancies, Clinically relevant, genetic profiling Ehsan Malek, MD1,2, E. Ricky Chan, PhD2,3*, Daniel Qu4*, Jane Reese2,5*, Robert Fox5*, Byung-Gyu Kim, PhD, DVM2,6*, Paolo F…
Source: ash.confex.comCategories: Hem/Oncs, Latest HeadlinesTweet-
Whole-Exome Sequencing Identifies a Somatic Cell Mutation Signature That Predicts Relapse Risk and Survival Probability in Multiple Myeloma [Dec 5, 2020] @EhsanMalekMD et al. #ASH21 Abstract 1355 https://t.co/lMZfsfMWCr #mmsm #cagenome
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Whole-genome sequencing [WGS] of multiple myeloma reveals oncogenic pathways are targeted somatically through multiple mechanisms [Apr 9, 2018] Phuc H. Hoang et al. @LeukemiaJnl https://t.co/NFLnBKDo3Y #mmsm #cagenome