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Mashup Score: 0Current Social Media Conversations about Genetics and Genomics in Health: A Twitter-Based Analysis - PubMed - 1 year(s) ago
This content analysis provides insight about the types of conversation related to genomics and health. Conversations about genomics are occurring on Twitter, and they frequently emphasize rare genetic diseases and genetic disorders. These discussions tend to be driven by key influencers who primaril …
Source: PubMedCategories: Hem/Oncs, Latest HeadlinesTweet
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Mashup Score: 9Advancing CAR T cell therapy through the use of multidimensional omics data - Nature Reviews Clinical Oncology - 1 year(s) ago
Data obtained using omics technologies can offer important insights into various aspects of chimeric antigen receptor (CAR) T cell therapy. In this Review, the authors provide an overview of the multidimensional profiling technologies that have been applied in investigations of CAR T cell therapy. They then discuss the ways in which multi-omics data obtained through such analyses can be used to…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
In a new Review now live online, Michael Green, Leng Han and co-author discuss the opportunities to advance CAR T cell therapy through the use of multidimensional omics data, as well as the associated challenges: https://t.co/IZhSqo75uM #ImmunoOnc #cagenome #cametab #caproteo https://t.co/gQ0H6Si8ZP
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Mashup Score: 1Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade Glioma - 1 year(s) ago
PURPOSE In patients with diffuse low-grade glioma (LGG), the extent of surgical tumor resection (EOR) has a controversial role, in part because a randomized clinical trial with different levels of EOR is not feasible. METHODS In a 20-year retrospective cohort of 392 patients with IDH-mutant grade 2 glioma, we analyzed the combined effects of volumetric EOR and molecular and clinical factors on…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
👀 Check out what’s popular this week in #JCO: Interactive Effects of Molecular, Therapeutic, and Patient Factors on Outcome of Diffuse Low-Grade #Glioma 👉 https://t.co/b2eoVExAsC #BTSM #cagenome @HerveyJumper @AnnetteMolinar2 https://t.co/4gqifuNmmk
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Mashup Score: 0
New genetic analyses demonstrate that the presence of low-frequency subclonal populations, including high-risk subclones, at diagnosis in multiple myeloma can contribute to disease relapse and poor clinical outcomes. Thus, sensitive detection approaches are required to detect these subclones at diagnosis together with innovative treatment strategies to eradicate low-frequency, high-risk subclones…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
In this News & Views entitled 'From little subclones grow mighty oaks', now live online, Eileen Boyle & Faith Davies discuss the detection of high-risk subclones present at diagnosis in patients with multiple myeloma: https://t.co/VeR4zDR6MJ #MMSM #camoldx #hemeonc #cagenome https://t.co/useKGYkZfr
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Mashup Score: 0Advances in the clinical management of uveal melanoma - Nature Reviews Clinical Oncology - 1 year(s) ago
Although almost all patients with uveal melanoma have localized disease at diagnosis, and despite effective treatment of the primary tumour, metastatic recurrence is common and holds a dismal prognosis. Unlike its cutaneous counterpart, therapeutic advances for uveal melanoma have not been forthcoming, although the recent approval of the first systemic therapy for this disease has ushered in a…
Source: NatureCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
In a new Review now live online, Richard Carvajal et al. discuss key advances in the clinical management of uveal melanoma: https://t.co/HxbrnrNngV @ColumbiaCancer #melsm #ImmunoOnc #medonc #camets #cagenome https://t.co/asJchnEMSF
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Mashup Score: 0JNCCN 360 - Bladder - Genomic Analysis May Guide Treatment Selections in Metastatic Urothelial Cancer - 1 year(s) ago
By: Emily Rhode Posted: Thursday, December 8, 2022 A recent study published in Nature Communications outlines the findings of UC-GENOME (the Urothelial Cancer Genomic Analysis to Improve Patient Outcomes and Research), a foundational genomic characterization of patients with metastatic urothelial carcinoma. Matthew I….
Source: jnccn360.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Genomic Analysis May Guide Treatment Selections in Metastatic #UrothelialCancer, Read About it At #JNCCN360: https://t.co/7nRuIhxDAX #cagenome #BLCSM https://t.co/fCYo8fVqPL
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Mashup Score: 1
PURPOSE CALGB 40603 (NCT00861705), a 2 × 2 randomized phase II trial, demonstrated that adding carboplatin or bevacizumab to weekly paclitaxel (wP) followed by doxorubicin and cyclophosphamide significantly increased the pathologic complete response (pCR) rate in stage II-III triple-negative breast cancer. We now report long-term outcomes (LTOs) and correlative science end points. PATIENTS AND…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Featured in Best of #JCO Breast Cancer Edition: CALGB 40603 (Alliance): Long-Term Outcomes and Genomic Correlates of Response & Survival After Neoadjuvant Chemo With or Without Carboplatin and Bevacizumab in Triple-Negative #BreastCancer https://t.co/7bPWI1EBRD #BCSM #cagenome
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Mashup Score: 0Paper: Clonal Dynamics after Haematopoietic Stem Cell Transplantation Using Genome-Wide Somatic Mutations - 1 year(s) ago
Oral and Poster Abstracts Oral 701. Experimental Transplantation: Basic and Translational: Novel Translational Approaches in Transplantation Research, Fundamental Science, Biological therapies, adult, Translational Research, CHIP, hematopoiesis, Therapies, Biological Processes, Study Population, Human, Transplantation Michael Spencer Chapman, MBBS1,2*, C….
Source: ash.confex.comCategories: Hem/Oncs, Latest HeadlinesTweet-
Clonal Dynamics after Haematopoietic Stem Cell Transplantation Using Genome-Wide Somatic Mutations [Dec 11, 2022] @doctor_msc et al. Abst 651 #ASH22 https://t.co/WfhXZk1WwJ #mmsm #cagenome #bmtsm https://t.co/Xi61zwKk7H
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Mashup Score: 0Exploring the Next Frontier in Non–Small-Cell Lung Cancer With High MET and Mutated Epidermal Growth Factor Receptor - 1 year(s) ago
© 2022 by American Society of Clinical OncologyConception and design: All authorsManuscript writing: All authorsFinal approval of manuscript: All authorsAccountable for all aspects of the work: All authorsAUTHORS’ DISCLOSURES OF POTENTIAL CONFLICTS OF INTERESTExploring the Next Frontier in Non–Small-Cell Lung Cancer With High MET and Mutated Epidermal Growth Factor ReceptorThe following…
Source: Journal of Clinical OncologyCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
🧐 #JCO #UnderstandingThePathway: Exploring the next frontier in non-small-cell #LungCancer w/ high MET & mutated EGFR 🎯 https://t.co/LLw2bA8AcI #LCSM #NSCLC #cagenome @DrRaviSalgia https://t.co/itBdLayTQT
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Mashup Score: 0JNCCN 360 - Breast - Identifying Genomic Characteristics of Breast Cancers Linked to PTEN Hamartoma Tumor Syndrome - 2 year(s) ago
By: Joseph Fanelli Posted: Thursday, November 3, 2022 Findings presented in the American Journal of Human Genetics demonstrated a characteristic genomic landscape in PTEN hamartoma tumor syndrome (PHTS) breast cancers, an entity that is currently treated similarly to sporadic breast cancers. These findings indicate a…
Source: jnccn360.orgCategories: Hem/Onc News and Journals, Latest HeadlinesTweet-
Identifying Genomic Characteristics of Breast Cancers Linked to #PTEN Hamartoma Tumor Syndrome on #JNCCCN360: https://t.co/bVrthBSHOV #BreastCancer #BCSM #cagenome https://t.co/dK0deFOR5p
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Current Social Media Conversations about Genetics and Genomics in Health: A Twitter-Based Analysis [Nov, 2018] Allen et al. Public Health Genomics https://t.co/30k52IfxlW #geneticcounselors #PrecisionMedicine #cagenome