• Mashup Score: 1

    Read American College of Rheumatology clinical practice guidelines for the prevention and treatment of vasculitis.

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    • Key theme in new ACR/@VasculitisFound clinical practice guideline: Increasing use of biologics to treat systemic #vasculitis—e.g., #tocilizumab for #GCA, #rituximab for #ANCA-associated vasculitis, #mepolizumab for #EGPA → https://t.co/mvCfVlxnsF https://t.co/2TbVDkawKU

  • Mashup Score: 2

    Primary and secondary ANCA-negative pauci-immune necrotizing glomerulonephritis. Pauci-immune necrotizing glomerulonephritis (PING) is a small-vessel kidney vasculitis usually associated with the presence of anti-neutrophil cytoplasm antibodies (ANCA) directed against the myeloperoxidase or the proteinase 3. A minority of patients with PING do not have this type of ANCA. To describe the clinical…

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    • ANCA-Negative Pauci-immune Necrotizing Glomerulonephritis: A Case Series and a New Clinical Classification https://t.co/XCyry3BYBm @RonsinCharles @LudivineLebour1 @MoglieQuintrec @karine_renaudin @AKI #ANCA #VisualAbstract https://t.co/fz0dtyi6lf

  • Mashup Score: 1

    A molecule released by platelets — cell fragments in the blood that form clots and stop or prevent bleeding — appears to contribute to the progression of ANCA-associated vasculitis (AAV) by triggering a defense mechanism carried out by white blood cells. Researchers now have identified a key…

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    • Scientists Identify Molecule That Triggers #AAV-related Defense Mechanism: “#Platelet #CXCL4 mediates #neutrophil extracellular traps formation in #ANCA-associated #vasculitis” https://t.co/A0HXRN88bH

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    Background Small studies suggest an association between ANCA-associated vasculitis (AAV) incidence and rurality, seasonality and socioeconomic deprivation. We examined the incidence of kidney biopsy-proven AAV and its relationship with these factors in the adult Scottish population. Methods Using the Scottish Renal Biopsy Registry, all adult native kidney biopsies performed between 2014 and 2018…

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    • Which factors may underlie geographic variation 🌏in #ANCA associated #vasculitis ? 🔴Seasonality ✅Rurality ▶️Important to consider socioeconomic status and health resources to reduce health disparities in #AAV 🔗https://t.co/K0HwXnhjIg https://t.co/hCqIg71ybi

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    StR training series: Vasculitis

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    • Trainees, make sure you join our #vasculitis StR training webinar tomorrow. Topics from Dr Sarah Fordham and @cmukhtyar include #ANCA vasculitis and a #GCA update, covering management, severe manifestations and treatment strategies. Book your spot: https://t.co/IzQbxOfyLK https://t.co/NYVSfbLH2W