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    Background/aims To further validate the Vision Impairment in Low Luminance (VILL) questionnaire, which captures visual functioning and vision-related quality of life (VRQoL) under low luminance, low-contrast conditions relevant to age-related macular degeneration (AMD). Methods The VILL was translated from German into English (UK), Danish, Dutch, French, Italian and Portuguese. Rasch analysis was used to assess psychometric characteristics of 716 participants (65% female, mean age 72±7 years, 82% intermediate AMD) from the baseline visit of the MACUSTAR study. In a subset of participants (n=301), test–retest reliability (intraclass correlation coefficient (ICC) and coefficient of repeatability (CoR)) and construct validity were assessed. Results Four items were removed from the VILL with 37 items due to misfit. The resulting Vision Impairment in Low Luminance with 33 items (VILL-33) has three subscales with no disordered thresholds and no misfitting items. No differential item function

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    • How do you assess vision impairment from patients' standpoint in #AMD? The Vision Impairment in Low Luminance (#VILL) can capture patient-reported outcomes in future trials, according to the #MACUSTAR study: https://t.co/FQsu45jS0j ⭐ 🤩 #retina #ophthalmology #ophthotwitter https://t.co/QiP95Xs1AL

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    By Christine Yue Leonard, Senior Associate Editor W ithin the space of just a few years, several new retinal treatments have been ap proved for wet age-related macular degeneration, diabetic macular edema and retinal vein occlusion, promising increased durability and better drying. These toolbox additions are encouraging for treating resistant and newly diagnosed patients. As with any newly available treatment, uptake is often gradual, and doctors may wonder whether it’s worth it to stock another drug.

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    • Expanding Retina’s Armamentarium Here’s how specialists are using the latest treatments for wet AMD, DME and RVO. Read the feature from the new August issue: https://t.co/Ivh6dASTL6 #retina #ophthalmology #ophthalmologist #retinaspecialist #AMD #maculardegeneration https://t.co/tKu7VNsrg0