• Mashup Score: 0

    Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary forms of chronic kidney disease. Mutations within PKD1 or PKD2 lead to innumerable fluid-filled cysts in the kidneys and in some instances, end-stage renal disease (ESRD). Affected individuals have a 50% chance of passing the mutation to each of their offspring. Assisted reproductive technology using…

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    • From our Pregnancy and Kidney Disease collection: Preimplantation Genetic Diagnosis Counseling in Autosomal Dominant Polycystic Kidney Disease https://t.co/W9SJh5LICl (FREE temporarily) @ndahl48 @YaleNephrology #ADPKD https://t.co/ZzwXIrXmLy

  • Mashup Score: 14

    Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder that leads to kidney failure and has few treatment options. Metformin is well tolerated and safe in other patient populations. The primary objective of this clinical trial was to determine the safety and tolerability of metformin in patients with ADPKD and without diabetes mellitus.

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    • RT @AJKDonline: Metformin Therapy in Autosomal Dominant Polycystic Kidney Disease: A Feasibility Study https://t.co/OPLpA3RJdB @michelcho…

    • Metformin Therapy in Autosomal Dominant Polycystic Kidney Disease: A Feasibility Study https://t.co/OPLpA3RJdB @michelchonchol @CUAnschutz #ADPKD https://t.co/CHxK4Lg9DJ

  • Mashup Score: 12
    NEJM Evidence : - 3 year(s) ago

    Original Article Prescribed Water Intake in Autosomal Dominant Polycystic Kidney DiseaseGopala K. Rangan, Ph.D. and OthersIn patients with autosomal dominant polycystic kidney disease (ADPKD), drinking more water could potentially reduce urine osmolality and suppress arginine vasopressin release and decrease the rate of kidney cyst growth and its associated organ…

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    • Prescribed water intake alone is not associated with slowing growth of #ADPKD cysts. #KidneyWk @gopi_rangan @gopi_rangan @PKDFoundation @gratefull080504 #PKD https://t.co/kX9dWyivBo via @NEJMEvidence

    • Posted at 1PM on @NEJMEvidence synchronized with presentation at #KidneyWk: Prescribed Water Intake in Autosomal Dominant Polycystic Kidney Disease by Gopala K. Rangan, Ph.D. and Others https://t.co/vx4LZ2mNQv https://t.co/b1KRCV7xbq