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A whole-genome sequencing study of Korean individuals with Parkinson’s disease (PD) has identified several new genetic risk factors, ranging from single nucleotide variations (SNVs) to larger DNA deletions. PD is the second most prevalent neurodegenerative disease globally, but most studies have focused on SNVs in European populations. Using whole-genome sequencing, Ji-Hye Oh at the University of…
Source: NatureCategories: Healthcare Professionals, Latest HeadlinesTweet
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Background: Vascular calcification is a prevalent complication in chronic kidney disease and contributes to increased cardiovascular morbidity and mortality. XBP1 (X-box binding protein 1), existing
Source: Circulation ResearchCategories: Cardiology News and Journals, Latest HeadlinesTweet
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While immune responses induced by bacterial infection may be leveraged to fight cancer, few bacterial proteins have been investigated for anticancer potential. Here, the bacterial protein and virulen…
Source: Wiley Online LibraryCategories: Hem/Onc News and Journals, Latest HeadlinesTweet
Whole-genome sequencing reveals an association between small genomic #deletions and an increased risk of developing #Parkinson’s disease https://t.co/zrLYiNrZTo #WGS #CNV #GPR27 #enhancer #SNCA #dopamine #TCF7L2 #βcatenin #PM101