The increasing body of literature describing the role of host factors in COVID- 19 pathogenesis demonstrates the need to combine diverse, multi-omic data to evaluate and substantiate the most robust evidence and inform development of therapies. Here we present a dynamic ranking of host genes implicated in human betacoronavirus infection (SARS-CoV-2, SARS-CoV, MERS-CoV, seasonal coronaviruses)….
Dr. Jeilan is Director of Cardiology at the Aga Khan University Hospital, Nairobi and an interventional cardiologist with a broad expertise in Coronary Angioplasty and…
Most trials that have shown a benefit of beta-blocker treatment after myocardial infarction included patients with large myocardial infarctions and were conducted in an era…
Heart failure (HF) is a well-described final common pathway for a broad range of diseases however substantial confusion exists regarding how to describe, study, and…
The RE-AIM planning and evaluation framework was conceptualized two decades ago. As one of the most frequently applied implementation frameworks, RE-AIM has …
Empagliflozin improves cardiovascular outcomes in patients with heart failure, patients with type 2 diabetes who are at high cardiovascular risk, and patients with chronic kidney…
Abstract. Health and health care access in the United States are plagued by high inequality. While machine learning (ML) is increasingly used in clinical settin
Review Article from The New England Journal of Medicine — Key Issues as Wearable Digital Health Technologies Enter Clinical Care
Fertility is declining globally, with rates in more than half of all countries and territories in 2021 below replacement level. Trends since 2000 show considerable…
This randomized clinical trial of older adults in Washington state assesses whether a sedentary behavior reduction intervention can reduce sitting time and improve blood pressure.
Background Undiagnosed and untreated hypertension is a main driver of cardiovascular disease and disproportionately affects persons living with HIV (PLHIV) in low- and middle-income countries.…
