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Mashup Score: 4Causal relationships between pain, medical treatments, and knee osteoarthritis: a graphical causal model to guide analyses - 6 month(s) ago
Randomized controlled trials (RCTs) are a gold standard for estimating benefits of clinical interventions, but their decision-making utility can be limited by relatively short follow-up time. Longer-term follow-up of RCT participants is essential to support treatment decisions. However, as time from randomization accrues, loss to follow-up and competing events can introduce biases and requires covariate adjustment even for intention-to-treat effects. We describe a process for synthesizing expert knowledge and apply this to long-term follow-up of an RCT of treatments for meniscal tear in patients with knee osteoarthritis.
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Mashup Score: 1Associations between pain sensitization and measures of physical function in people with hand osteoarthritis: Results from the Nor-Hand study - 7 month(s) ago
To examine whether pain sensitization is associated with hand and lower extremity function in people with hand osteoarthritis (OA) in the Nor-Hand study.
Source: www.oarsijournal.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 2A new art to treating osteoarthritis pain? - 7 month(s) ago
Osteoarthritis (OA) pain involves peripheral and central neural pathways, as well as interactions between multiple cell types and soluble mediators.1 Although therapeutic targeting of peripheral OA pain pathways might prove simpler and be associated with fewer side effects, the complexity of OA pain means that it will likely be the case that what works for one patient will be inefficacious for another. Consequently, it is important to further our understanding of OA pain mechanisms to develop new treatments and thus expand the clinician’s therapeutic arsenal.
Source: www.oarsijournal.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 1The emperor's new clothes? - 7 month(s) ago
The ‘Emperor’s New Clothes’ is a classic Danish tale written by Hans Christian Andersen. The story has been translated into over 100 languages. In brief, the plot is about a vain Emperor who loves spending the state’s money on expensive clothing. A couple of swindlers posing as weavers are offering the Emperor clothes made of the most delicate fabric that is said to be visible only to those who are fit for their office and not incompetent. The Emperor hires the swindlers, who set up their looms and pretend to weave.
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Mashup Score: 0Current Issue Table of Contents: Osteoarthritis and Cartilage - 1 year(s) ago
EDITORIALRecreational running is not bad for healthy people’s joints — it is time to study the safety of running in people with osteoarthritisJ.-F. Esculier,C. BartonPublished online: November 15, 2022p135-137Full-Text HTMLPDF COMMENTARIESAll that glistens is not goldP. Richette,A. LatourtePublished online: October 25, 2022p138-139Full-Text HTMLPDF Evidence…
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Mashup Score: 1Current Issue Table of Contents: Osteoarthritis and Cartilage - 1 year(s) ago
Acknowledgement to Reviewers 2022D. Hunter,A.-M. MalfaitPublished online: November 24, 2022p1-5Full-Text HTMLPDF EDITORIALSDisentangling the molecular interplays between subchondral bone and articular cartilage in estrogen deficiency-induced osteoarthritisSantos Castañeda,Esther F. Vicente-RabanedaPublished online: September 27, 2022p6-8Full-Text HTMLPDF …
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Mashup Score: 2Current Issue Table of Contents: Osteoarthritis and Cartilage - 1 year(s) ago
EDITORIALWaiting for orthopedic surgery — are we underestimating the impacts on people with advanced osteoarthritis?I.N. AckermanPublished online: September 02, 2022p1545-1546Full-Text HTMLPDF FUNDAMENTALS OF OACellular therapy and tissue engineering for cartilage repairA. Zelinka,A.J. Roelofs,R.A. Kandel,C. De BariPublished online: September 19, 2022p1547-1560Open AccessFull-Text…
Source: www.oarsijournal.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 0Current Issue Table of Contents: Osteoarthritis and Cartilage - 2 year(s) ago
EDITORIALSCausal inference from observational data and target trial emulationS.R. Jafarzadeh,T. NeogiPublished online: September 01, 2022p1415-1417Full-Text HTMLPDF Metformin as a potential disease-modifying agent in osteoarthritis: the present and the futureR.W.S. SitPublished online: August 24, 2022p1418-1419Full-Text HTMLPDF REVIEWSSystematic ReviewsDoes…
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Mashup Score: 0Current Issue Table of Contents: Osteoarthritis and Cartilage - 2 year(s) ago
REVIEWSNarrative reviewThe relationship between meniscal pathologies, cartilage loss, joint replacement and pain in knee osteoarthritis: a systematic reviewA. Ghouri,S. Muzumdar,A.J. Barr,…C. Murdoch,S.R. Kingsbury,P.G. ConaghanPublished online: August 10, 2022p1287-1327Open AccessFull-Text HTMLPDF Supplemental MaterialsORIGINAL PAPERSBasic and translational researchBiglycan…
Source: www.oarsijournal.comCategories: Latest Headlines, RheumatologyTweet
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Mashup Score: 2Current Issue Table of Contents: Osteoarthritis and Cartilage - 2 year(s) ago
EDITORIALSEditorial for ‘Quantitative T2 and T1ρ mapping are sensitive to ischemic injury to the epiphyseal cartilage in an in vivo piglet model of Legg-Calvé-Perthes disease’A.F. Lombardi,E.Y. Chang,J. DuPublished online: July 05, 2022p1155-1156Full-Text HTMLPDF As the prevalence of obesity increases, rationing arthritis care is not the answerA. Brown,B. RaviPublished online:…
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Causal relationships between pain, medical treatments, and knee osteoarthritis: a graphical causal model to guide analyses https://t.co/4sZMkP30aK via @EpiEllie et al https://t.co/7InKTRS0ym