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Mashup Score: 2
To investigate the occurrence of meniscal calcifications in individuals with and without knee osteoarthritis (OA). Additionally, we aim to identify the specific types of calcifications: basic calcium phosphate (BCP) and calcium pyrophosphate dihydrate (CPP).
Source: www.oarsijournal.comCategories: General Medicine News, RheumatologyTweet
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Mashup Score: 5
To evaluate the efficacy and safety of intra-articular injections of a novel aggrecan mimetic, SB-061, in subjects with knee osteoarthritis (OA).
Source: www.oarsijournal.comCategories: General Medicine News, RheumatologyTweet-
NEW @OACJournal 📢 Do intra-articular injections with SB-061 (aggrecan mimetic) improve structural changes in knee #OA? That and more by Bihlet et al. in https://t.co/am6XFizhOo https://t.co/fe5DILiVxM
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Mashup Score: 16
To monitor serum concentrations of the aggrecan alanine-arginine-glycine-serine (ARGS) neoepitope in a clinical trial of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-5 inhibition as disease-modifying therapy of knee osteoarthritis, and to investigate relationships between reduction in ARGS and change in cartilage thickness, knee-related pain and function.
Source: www.oarsijournal.comCategories: General Medicine News, RheumatologyTweet-
🆕 NOV's #editorschoice is from @lunduniversity What are the effects of systemic inhibition of ADAMTS-5 in knee #osteoarthritis? Read more from the #ROCCELLA trial and Larsson et al. as they investigate further - https://t.co/jKNUVg0uQM https://t.co/8YSBdWPy87
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Mashup Score: 7IL-23p19 in osteoarthritic pain and disease - 23 day(s) ago
We have previously reported that the interleukin-23 p19 subunit (IL-23p19) is required for experimental inflammatory arthritic pain-like behavior and disease. Even though inflammation is often a characteristic feature of osteoarthritis (OA), IL-23 is not usually considered as a therapeutic target in OA. We began to explore the role of IL-23p19 in OA pain and disease utilizing mouse models of OA and patient samples.
Source: www.oarsijournal.comCategories: General Medicine News, RheumatologyTweet-
🌟Our #BasicScience #EditorsChoice for November is this brief report from Lee et al. 🌟 Great work to all authors: @TLupancu @AdrianAchuthan Access this work: https://t.co/sUXh1L50H9 https://t.co/QLJGb2Eako
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Mashup Score: 8Macrophage-derived PDGF-BB modulates glycolytic enzymes expression and pyroptosis in nucleus pulposus cells via PDGFR-β/TXNIP pathway - PubMed - 1 month(s) ago
The absence of PDGF-BB originating from macrophages expedites the advancement of IVDD, whereas the application of PDGF-BB treatment holds the potential for retarding intervertebral disc degeneration in the human body.
Source: pubmed.ncbi.nlm.nih.govCategories: General Medicine News, RheumatologyTweet-
Zheng et al. aimed to investigate the significance of #macrophage infiltration and the role of macrophage-secreted platelet-derived growth factor-BB in #IVDD progression. 📖 More: https://t.co/tCqAFRtgz9 https://t.co/yPAYK5soXZ
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Mashup Score: 13Is there a role for autologous conditioned serum injections in osteoarthritis? A systematic review and meta-analysis of randomised controlled trials - 1 month(s) ago
To assess whether patient reported outcome measures (PROMs) improve after autologous conditioned serum (ACS) administration in patients with osteoarthritis.
Source: www.oarsijournal.comCategories: General Medicine News, RheumatologyTweet-
🌶️ in this month's @OACJournal "There is currently insufficient data to support the use of autologous conditioned serum injections in #osteoarthritis" Read for free from Curtis et al @BristolBRC - https://t.co/1vnT1hl2ws https://t.co/9JSIaD7KrK
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Mashup Score: 7
We here explore whether observed treatment effects of a putative disease-modifying osteoarthritis drug (DMOAD) are greater when cartilage morphometry is performed with rather than without knowledge of magnetic resonance imaging (MRI) acquisition order (unblinded/blinded to time point).
Source: www.oarsijournal.comCategories: General Medicine News, RheumatologyTweet-
Are #DMOAD treatment effects greater when MRIs are read unblinded to order? #kneeosteoarthritis Read more in this month's @OACJournal issue from Eckstein at al. here - https://t.co/g1oCbnexah https://t.co/dBsOWJtdzS
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Mashup Score: 14
To investigate relationships between static foot posture, dynamic plantar foot forces and knee pain in people with medial knee osteoarthritis (OA).
Source: www.oarsijournal.comCategories: General Medicine News, RheumatologyTweet-
NEW this month @OACJournal ✅ Higher plantar foot forces when walking 🚶♂️ seen in those with knee #osteoarthritis Read more from @KadePaterson @KimBennell @AnurikaDeSilva @HinmanRana @CHESM_unimelb @UniMelbMDHS at https://t.co/dvqy2nQ9R3 https://t.co/9Wp1FXkEop
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Mashup Score: 11
Join Osteoarthritis & Cartiliage Journal editors, David Hunter and Anne-Marie Malfait, for a one hour informative session about OAC quality and submission requirements. There will be time for questions and you may submit a question for consideration in advance of the session. There is no cost to participate, however, you must register in order to receive access to the webinar.
Source: ahint.zoom.usCategories: General Medicine News, RheumatologyTweet-
✉️📫 Authors looking for tips to publish in @OACJournal 📣 Join @ProfDavidHunter @AM_Malf and Annie Zhao from @ElsevierConnect in this interactive webinar on Nov 14! Link 👉🏻 https://t.co/uxsDgXFdhD https://t.co/Q9aqlVleIJ
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Mashup Score: 3Effect of isometric quadriceps exercise on local microcirculation of the infrapatellar fat pad in female patients with knee osteoarthritis - 2 month(s) ago
To elucidate the local microcirculation of the infrapatellar fat pad (IFP) in patients with knee osteoarthritis (KOA) by determining the changes in IFP hardness and hemoglobin concentration during isometric quadriceps exercise (IQE).
Source: www.oarsijournal.comCategories: General Medicine News, RheumatologyTweet-
⚡️ Just published!⚡️ Local #fatpad #microcirculation may be impaired in those with knee #OA due to a lack of mechanical stress Read more from authors Nakanishi et al @Takapon_PT_PhD @morinomiya_univ at https://t.co/cs1tadd7fb https://t.co/pxefHcFDvJ
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New #OAC #BasicScience This work by Shakya et al. found that basic calcium phosphate crystals are almost exclusively found in menisci from OA patients, while calcium pyrophosphate has similar prevalence in menisci from subjects with and without OA. 🔗 : https://t.co/PBaVQSspiE https://t.co/ivOOKVIX9b