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Mashup Score: 44A Common Pathway in the Brain That Enables Addictive Drugs to Hijack Natural Reward Processing Has Been Identified by Mount Sinai - 20 day(s) ago
Mount Sinai researchers, in collaboration with scientists at The Rockefeller University, have uncovered a mechanism in the brain that allows cocaine and morphine to take over natural reward processing systems. Published online in Science on April 18, these findings shed new light on the neural underpinnings of drug addiction and could offer new mechanistic insights to inform basic research, clinical practice, and potential therapeutic solutions. “While this field has been explored for decades, our study
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 11Immune Cells Identified as Key Players in Brain Health - 2 month(s) ago
Using novel genetic and genomic tools, researchers at the Icahn School of Medicine at Mount Sinai have shed light on the role of immune cells called macrophages in lipid-rich tissues like the brain, advancing our understanding of Alzheimer’s and other diseases. The study, published in the March 6 online issue of Nature Communications, represents a step forward in understanding immune cell regulation and its impact on disease progression. The researchers initially studied genes controlling macrophages,
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Mashup Score: 7
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine [10.1038/s43856-024-00437-7], addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 7
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine [10.1038/s43856-024-00437-7], addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 20First-in-Human Study Reveals Dopamine and Serotonin Have Overlapping, Yet Distinctive Roles That Influence Social Behavior - 2 month(s) ago
New research conducted by researchers from the Icahn School of Medicine at Mount Sinai in collaboration with an international team of neuroscientists, clinicians, and computational scientists reveals, for the first time, the roles of the neurotransmitters dopamine and serotonin in human social behaviors. The study, published Monday, February 26, in Nature Human Behavior, provides direct evidence from the human brain that rapid changes in these two neurotransmitters reflect context and value signals
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet-
PRESS RELEASE! New research conducted by @xiaosigu & Brian Kopell, MD, in collaboration w/ an international team of researchers, reveals, for the first time, roles of the neurotransmitters #Dopamine & #Serotonin in human social behaviors.👉@NatureHumBehav https://t.co/IJCZxHMSDU https://t.co/Kz1yxMC3ty
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Mashup Score: 8
Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients. The study, published in the February 28 online issue of Communications Medicine [10.1038/s43856-024-00437-7], addresses critical challenges in dementia care by pinpointing patients at high risk of near-term death and uncovers the factors that drive this risk. Unlike previous studies that focused on diagnosing dementia, this
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 4Center for Neuromodulation in New York City - 3 month(s) ago
Neuromodulation is particularly appropriate for people with neurological conditions, refractory psychiatric disorders, movement disorders, and chronic pain.
Source: www.mountsinai.orgCategories: General Medicine News, Future of MedicineTweet
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Mashup Score: 21Global Taskforce of Scientists Develop a Unifying Framework for the Human Affectome - 3 month(s) ago
To improve upon current scientific understanding of how our feelings, emotions, and moods relate to and impact human behavior — known in the field as “affective science” — an interdisciplinary task force of 173 scientists from 23 countries, has created an integrative framework that encompasses the enormous array of affective phenomena that exist within the Human Affectome. This organizational scheme allows vastly different scientific interests to relate to one another within the same theoretical framework,
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Mashup Score: 34Mount Sinai Study Shows That Circulating Immune Cells Drawn to the Brain During Stress Can Control Emotional Behaviors - 3 month(s) ago
Mount Sinai researchers have shown for the first time that immune cells called monocytes, derived in the bone marrow and released into the bloodstream, can be drawn during stress into sites in the brain that control emotional behaviors. There, they release an enzyme called matrix metalloproteinase 8 (MMP8) that breaks down proteins and restructures the brain to alter the function of neurons and, ultimately, impair social behavior and reward. These data establish a novel mechanism by which the immune
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet-
PRESS RELEASE: @FlurinCathomas @ScottRussoPhD, et al. show that "Circulating Immune Cells Drawn to the Brain During Stress Can Control Emotional Behaviors". Here, they have ID'd novel ‘body-mind mechanism’ that links #ChronicStress to #Depression @Nature👉https://t.co/Y7xkmtFihm https://t.co/x2jYK6yQVC
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Mashup Score: 95AI-Driven Study Redefines Right Heart Health Assessment With Novel Predictive Model - 4 month(s) ago
In a milestone study, researchers from the Icahn School of Medicine at Mount Sinai have harnessed the power of artificial intelligence (AI) to enhance the assessment of the heart’s right ventricle, which sends blood to the lungs. Conducted by a team using AI-enabled electrocardiogram (AI-ECG) analysis, the research demonstrates that electrocardiograms can effectively predict right-side heart issues, offering a simpler alternative to complex imaging technologies and potentially enhancing patient outcomes.
Source: www.mountsinai.orgCategories: General Medicine News, General HCPsTweet
GROUNDBREAKING STUDY by researchers @IcahnMountSinai & @RockefellerUniv, have uncovered mechanism in the brain that allows drugs of abuse to take over natural reward processing systems. @EricJNestler @VaziriLab #FriedmanLab @JDCalebBrowne @tbw_owl @tbinoe👉https://t.co/NPPYydk5Ju https://t.co/r3JH5di50S