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Mashup Score: 26Researchers Unravel a Novel Mechanism Regulating Gene Expression in the Brain That Could Guide Solutions to Circadian and Other Disorders - 11 day(s) ago
A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells. By uncovering how these histone modifications influence the brain, the team has identified a novel mechanism for controlling circadian gene expression and
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 26Researchers Unravel a Novel Mechanism Regulating Gene Expression in the Brain That Could Guide Solutions to Circadian and Other Disorders - 12 day(s) ago
A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells. By uncovering how these histone modifications influence the brain, the team has identified a novel mechanism for controlling circadian gene expression and
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 0Experimental Cancer Therapy Shows Success in More Than 70 Percent of Patients in Global Clinical Trials - 17 day(s) ago
A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai. The therapy, known as a bispecific antibody, binds to both T cells and multiple myeloma cells and directs the T cells — white blood cells that can be enlisted to fight off diseases — to kill multiple myeloma cells. The researchers described this strategy
Source: www.mountsinai.orgCategories: General Medicine News, General HCPsTweet
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Mashup Score: 1Emergency airway puncture - 26 day(s) ago
Learn about Emergency airway puncture or find a doctor at Mount Sinai Health System.
Source: www.mountsinai.orgCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 38Novel Study Reveals How Aging Immune System Fuels Cancer Growth, Potentially Opening New Avenues for Prevention - 1 month(s) ago
A novel study by researchers at the Icahn School of Medicine at Mount Sinai addresses a critical yet under-explored question in cancer research: Why is aging the biggest risk factor for cancer? The study reveals how an aging immune system spurs tumor growth, offering new insights into cancer prevention and treatment, especially for older adults. Details on the findings were reported in the September 5 Online First Release of Science [DOI:10.1126/science.adn0327]. In preclinical models, the research team
Source: www.mountsinai.orgCategories: General Medicine News, Oncologists1Tweet
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Mashup Score: 10Study Reveals New Way to Unlock Blood-Brain Barrier, Potentially Opening Doors to Treat Brain and Nerve Diseases - 2 month(s) ago
Researchers at the Icahn School of Medicine at Mount Sinai have developed an innovative approach — demonstrated in mouse models and isolated human brain tissue — to safely and effectively deliver therapeutics into the brain, providing new possibilities for treating a wide range of neurological and psychiatric diseases. Published in the November 25 online issue of Nature Biotechnology [https://doi.org/10.1038/s41587-024-02487-7], the study introduces a first-of-its-kind blood-brain barrier-crossing
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet-
PRESS RELEASE! In a great collaboration, @yizhoudonglab @EricJNestler, et al. develop innovative approach to safely/effectively deliver therapeutics into the brain, providing possibilities for treating a wide range of neurological & psychiatric diseases. https://t.co/7BJZqMNT4V https://t.co/uw9Sdorneh
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Mashup Score: 10Study Reveals New Way to Unlock Blood-Brain Barrier, Potentially Opening Doors to Treat Brain and Nerve Diseases - 2 month(s) ago
Researchers at the Icahn School of Medicine at Mount Sinai have developed an innovative approach — demonstrated in mouse models and isolated human brain tissue — to safely and effectively deliver therapeutics into the brain, providing new possibilities for treating a wide range of neurological and psychiatric diseases. Published in the November 25 online issue of Nature Biotechnology [https://doi.org/10.1038/s41587-024-02487-7], the study introduces a first-of-its-kind blood-brain barrier-crossing
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet-
PRESS RELEASE! In a great collaboration, @yizhoudonglab @EricJNestler, et al. develop innovative approach to safely/effectively deliver therapeutics into the brain, providing possibilities for treating a wide range of neurological & psychiatric diseases. https://t.co/7BJZqMNT4V https://t.co/uw9Sdorneh
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Mashup Score: 22Mount Sinai Researchers Have Uncovered the Mechanism in the Brain That Constantly Refreshes Memory - 2 month(s) ago
Mount Sinai researchers have discovered for the first time a neural mechanism for memory integration that stretches across both time and personal experience. These findings, reported in Nature, demonstrate how memories stored in neural ensembles in the brain are constantly being updated and reorganized with salient information, and represent an important step in deciphering how our memories stay current with the most recently available information. This discovery could have important implications for
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet
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Mashup Score: 1After a Heart Attack, the Heart Signals to the Brain to Increase Sleep to Promote Healing - 2 month(s) ago
A heart attack can trigger a desire to get more sleep, allowing the heart to heal and reduce inflammation — and this happens because the heart sends special signals to the brain, according to a new Mount Sinai study. This research is the first to demonstrate how the heart and brain communicate with each other through the immune system to promote sleep and recovery after a major cardiovascular event. The novel findings, published October 30 in Nature, emphasize the importance of increased sleep after a
Source: www.mountsinai.orgCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 17Mount Sinai Team Shows AI Can Detect Serious Neurologic Changes in Babies in the NICU Using Video Data Alone - 2 month(s) ago
A team of clinicians, scientists, and engineers at Mount Sinai trained a deep learning pose-recognition algorithm on video feeds of infants in the neonatal intensive care unit (NICU) to accurately track their movements and identify key neurologic metrics. Findings from this new artificial intelligence (AI)-based tool, published November 11 in Lancet’s eClinicalMedicine, could lead to a minimally invasive, scalable method for continuous neurologic monitoring in NICUs, providing critical real-time insights
Source: www.mountsinai.orgCategories: General Medicine News, NeurologyTweet
PRESS RELEASE: EXCITED to share NEW STUDY from @themazelab! Findings from collaborative effort between @IcahnMountSinai & @MSKCancerCenter could eventually guide dvlpmnt of targeted therapies for conditions involving #CircadianRhythm disruptions. https://t.co/8yGW4FZ40K https://t.co/93gRyUkWQA