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Mashup Score: 18
Diabetes mellitus (DM) is a major public health issue and a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), which contributes to up to 80 % of deaths in individuals with diabetes.1 The elevated risk is primarily due to hyperglycemia-induced inflammation, oxidative stress, and endothelial dysfunction, leading to increased coronary plaque burden and rupture risk. Coronary Computed Tomography Angiography (CCTA) enables detailed assessment of plaque burden using metrics like Total Plaque Score (TPS), Total Stenosis Score (TSS), and Coronary Artery Calcium (CAC) Score.
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Mashup Score: 19Prognostic value of plaque burden assessed by coronary CT angiography in known coronary artery disease - 7 day(s) ago
We aimed to investigate in patients with known coronary artery disease (CAD) whether plaque burden assessed by coronary computed tomography angiography (CCTA) can predict subsequent all-cause mortality (ACM).
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Mashup Score: 5Comparative assessment of CAC and SIS plaque burden categories via AI-guided quantitative CT analysis - 9 day(s) ago
Extensive data demonstrate that coronary artery calcium (CAC) scoring powerfully stratifies cardiovascular risk beyond traditional risk factors.1 Budoff et al. showed in 25,253 asymptomatic individuals that adding CAC to risk models markedly improved prediction (C-index 0.61 to 0.81).1 CAC burden correlates with incident events in a graded manner: patients with CAC >400 have substantially higher rates of myocardial infarction and death compared to those with CAC = 0123. The segment involvement score (SIS), derived from coronary CT angiography (CCTA), quantifies the number of coronary segments (out of 16 or 17) with any plaque, regardless of severity.
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Mashup Score: 6Cost-effectiveness of coronary CT angiography in patients with chest pain: Comparison with myocardial single photon emission tomography - 10 day(s) ago
Coronary CT angiography (CCTA) has been proven accurate and is incorporated in clinical recommendations for coronary artery disease (CAD) diagnosis workup, but cost-effectiveness data, especially in comparison to other methods such as myocardial single photon emission CT (SPECT) are insufficient.
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Mashup Score: 13Association of coronary inflammation with plaque vulnerability and fractional flow reserve in coronary artery disease - 1 month(s) ago
The fat attenuation index (FAI) measured using coronary computed tomography angiography (CCTA) enables the direct evaluation of pericoronary adipose tissue composition and vascular inflammation. We aimed to investigate the association of fractional flow reserve (FFR) and plaque vulnerability with coronary inflammation.
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Mashup Score: 4Clinical impact of CCT-FFR as first-strategy in patients with symptomatic stable coronary artery disease: A systematic review and meta-analysis - 1 month(s) ago
Aims: Despite the promising results, the clinical implications of the CCT-FFR is already debated. This metanalysis aimed to determine the potential benefits of incorporating FFRCT into stable CAD management.Methods: After searching for studies comparing outcomes of patients with suspected stable CAD who underwent CCT-FFR as a first strategy versus non-urgent cardiovascular testing after a clinical judgment, we calculated odds ratios (ORs) and 95 % confidence intervals (CIs) using a random-effects or fixed-effects meta-analysis model depending on heterogeneity significance.
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Mashup Score: 44How early can atherosclerosis be detected by coronary CT angiography? Insights from quantitative CT analysis of serial scans in the PARADIGM trial - 2 month(s) ago
Non-obstructing small coronary plaques may not be well recognized by expert readers during coronary computed tomography angiography (CCTA) evaluation. Recent developments in atherosclerosis imaging quantitative computed tomography (AI-QCT) enabled by machine learning allow for whole-heart coronary phenotyping of atherosclerosis, but its diagnostic role for detection of small plaques on CCTA is unknown.
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Mashup Score: 6
The effectiveness of coronary computed tomography angiography (CTA) is hindered by high coronary calcium scores, which create blooming artefacts that obscure the coronary lumen and lead to inaccurate stenosis assessments.1 Spectral CT, utilizing multi-energy CT technology, allows data acquisition at different energy levels, improving coronary artery visualization, particularly in the presence of calcified plaques.2–4 This study evaluates the accuracy of coronary CTA using spectral CT in patients with high calcium scores (>500) using invasive coronary angiography as reference.
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Mashup Score: 9Racial differences in atherosclerosis and coronary plaque characteristics using enhanced AI quantification (RACE-AI) - 2 month(s) ago
Cardiac computed tomography angiography (CCTA) has become a cornerstone in cardiovascular risk assessment, allowing for the quantification of coronary artery disease (CAD) burden and characterization of high-risk plaque features associated with adverse outcomes. Coronary artery calcium (CAC) scoring, utilizing the Agatston method, has been extensively validated as a predictor of cardiovascular events, with calcified plaques considered more stable and non-calcified plaques (NCP) linked to heightened cardiovascular risk.
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Mashup Score: 28Modern CT Detector Technology and Innovations in Image Reconstruction Enhance Cardiovascular CT - 5 month(s) ago
Most advances in computed tomography (CT) scanner technology have been stimulated by the demand of higher spatial resolution and increased signal-to-noise ratio (SNR) required to image the coronary arteries. Innovations in CT detector technology and reconstruction techniques have been driven by these demands.
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The effect of #diabetes on #plaque, stenosis, and #CAC score - https://t.co/uz2jhoqoXh