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Mashup Score: 17De-escalation of antiplatelet therapy in patients with coronary artery disease: Time to change our strategy? - 4 day(s) ago
Since more than two decades, dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is considered the gold standard for patients with acute coronary syndrome (ACS) as well as for those with chronic coronary syndrome (CCS) undergoing percutaneous coronary intervention (PCI) [1]. The more potent P2Y12 inhibitors prasugrel and ticagrelor have shown to reduce ischemic events at the cost of increased bleeding compared with clopidogrel [2,3]. Therefore, a 12-month DAPT with potent P2Y12 inhibitors represents the standard-of-care after ACS and may be considered after PCI in CCS patients in specific high ischemic risk situations [4–6].
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Mashup Score: 37Association of non-cardiac comorbidities and sex with long-term Re-hospitalization for heart failure - 1 month(s) ago
Heart failure (HF) is a complex clinical syndrome, the course of which is usually complicated by concomitant comorbidities [1–6]. However, in spite of this long-held notion, the impact of non-cardiac comorbidities on long-term prognosis in patients with HF receiving contemporary management is not well defined. This is a relevant issue to address, as comorbidities such as chronic kidney or obstructive lung disease may limit, for instance, the ability to prescribe optimal HF therapy, reduce their effectiveness due to competing non-cardiac risk, or increase the risk of their side effects, with a negative impact on quality of life, and prognosis.
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Mashup Score: 1Hypertension and heart failure: A dangerous relationship with clinical implications - 1 month(s) ago
Heart failure (HF) is currently classified into three categories, according to left ventricular (LV) ejection fraction (LVEF): HF with reduced ejection fraction (HFrEF; LVEF <40%), HF with mid-range ejection fraction (HFmrEF; LVEF 40–49%) and HF with preserved ejection fraction (HFpEF; LVEF ≥50%). While HFrEF patients are usually male and have a history of coronary artery disease, acute myocardial infarction or idiopathic dilated cardiomyopathy, the clinical spectrum of HFpEF has proven to be much more heterogeneous.
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Mashup Score: 10Validating ChatGPT's role in systematic reviews and meta-analyses: A case study on GLP-1 receptor agonists and all-cause mortality - 2 month(s) ago
Dear Editor,
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Mashup Score: 1
Atrial fibrillation (AF) is the most common arrhythmia worldwide and it is associated with a 3–5-fold higher risk of stroke [1]. This risk has been significantly reduced after the introduction of oral anticoagulants (OAC), that should be prescribed in all patients who are not considered at very low-risk of thromboembolism (i.e.: CHA2DS2-VASc Score 0 in males and 1 in females) as recommended by current guidelines on AF [2–5].
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Mashup Score: 172024 European Society of Hypertension clinical practice guidelines for the management of arterial hypertension - 5 month(s) ago
The European Society of Hypertension (ESH) reported in 2023 its current Guidelines for the management of arterial hypertension [1]. Following their aim to summarize the best available evidence for all aspects of hypertension management, the Task Force of the 2023 Guidelines generated a comprehensive document covering almost 200 pages including 1736 references [1]. This document thus provides a valuable and comprehensive source of information for hypertension management. However, due to the length of the text and its complexity, not only primary care providers (e.g.
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Mashup Score: 632024 European Society of Hypertension clinical practice guidelines for the management of arterial hypertension - 5 month(s) ago
The European Society of Hypertension (ESH) reported in 2023 its current Guidelines for the management of arterial hypertension [1]. Following their aim to summarize the best available evidence for all aspects of hypertension management, the Task Force of the 2023 Guidelines generated a comprehensive document covering almost 200 pages including 1736 references [1]. This document thus provides a valuable and comprehensive source of information for hypertension management. However, due to the length of the text and its complexity, not only primary care providers (e.g.
Source: www.ejinme.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 632024 European Society of Hypertension clinical practice guidelines for the management of arterial hypertension - 5 month(s) ago
The European Society of Hypertension (ESH) reported in 2023 its current Guidelines for the management of arterial hypertension [1]. Following their aim to summarize the best available evidence for all aspects of hypertension management, the Task Force of the 2023 Guidelines generated a comprehensive document covering almost 200 pages including 1736 references [1]. This document thus provides a valuable and comprehensive source of information for hypertension management. However, due to the length of the text and its complexity, not only primary care providers (e.g.
Source: www.ejinme.comCategories: General Medicine News, CardiologistsTweet
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Mashup Score: 1Artificial intelligence in scientific medical writing: Legitimate and deceptive uses and ethical concerns - 6 month(s) ago
The ghost-writer potential of ChatGPT and related AI tools has been widely discussed in many editorials and essays. Yet, general AI models to-date have failed to fully utilize medical language and this still places some limits to applications in medical science and healthcare [2]. Open-domain question answering firstly attracted the interest of the natural language processing (NLP) community and gave rise to a subset of sources that includes large-scale, multi-subject, and multi-choice datasets for medical domain question answering.
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Mashup Score: 462023 ESH Guidelines. What are the main recommendations? - 6 month(s) ago
Generally, Clinical Practice Guidelines (CPG) are evidence-based recommendations, presented as summaries of the best available literature, which are aimed to assist doctors and other health care professionals in the management of patients with a given disease. In the field of hypertension, as well as in other fields, the recommendations in CPG should be easy to implement in routine clinical practice [1]. CPG are intended to provide guidance, recognizing that clinicians should make recommendations that are best suited to meet the needs of individual patients.
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De-escalation of antiplatelet therapy in patients with coronary artery disease: Time to change our strategy? - European Journal of Internal Medicine https://t.co/rwnRPrWpNT one of the most read according to #EJINME