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Mashup Score: 5Exercise as a treatment for depression - 3 day(s) ago
A 2023 meta-analysis of randomized controlled trials (RCTs) found that supervised, group or non-group, moderate- or vigorous-intensity, aerobic or resistance exercises (excluding mind–body activities such as yoga) decreased depressive symptoms among participants with depression, with a number
Source: www.cmaj.caCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 0Canada’s crisis of primary care access: Is expanding residency training to 3 years a solution? - 7 day(s) ago
KEY POINTS In 2022, The College of Family Physicians of Canada (CFPC) published its final report of the Outcomes of Training Project, including the recommendation to extend family medicine residency training from 2 to 3 years.[1][1] Through an expanded training program, the CFPC’s goal is to
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Mashup Score: 7
Treating to intensive glycemic targets (glycosylated hemoglobin [A1c] < 7%) increases the risk of adverse events and is unlikely to provide benefit given the reduced life expectancy of these patients.[1][1] Guidelines recommend individualized glycemic targets (i.e., A1c < 8.5%) in older adults with
Source: www.cmaj.caCategories: General Medicine News, Hem/OncsTweet
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Mashup Score: 42Renal denervation for uncontrolled hypertension - 1 month(s) ago
KEY POINTS In 2021, about 5.8 million people in Canada were living with hypertension.[1][1] Despite the availability of pharmacotherapy, hypertension is a leading cause of death and disability globally, and in Canada, rates of treatment and control are declining.[1][1] Controlled hypertension is
Source: www.cmaj.caCategories: General Medicine News, NephrologyTweet
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Mashup Score: 42Renal denervation for uncontrolled hypertension - 1 month(s) ago
KEY POINTS In 2021, about 5.8 million people in Canada were living with hypertension.[1][1] Despite the availability of pharmacotherapy, hypertension is a leading cause of death and disability globally, and in Canada, rates of treatment and control are declining.[1][1] Controlled hypertension is
Source: www.cmaj.caCategories: General Medicine News, NephrologyTweet
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Mashup Score: 5Tripe palm: a paraneoplastic manifestation of gastric cancer - 2 month(s) ago
A 73-year-old man presented with a warty thickening of the skin on his hands and feet, which had been present for more than 1 year. He also reported general weakness, poor appetite and a weight loss of 8 kg over 6 months. The palms of his hands and soles of his feet had a rugose appearance with a
Source: www.cmaj.caCategories: General Medicine News, General HCPsTweet
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Mashup Score: 20Advances in the management of renal cell carcinoma - 2 month(s) ago
KEY POINTS Renal cell carcinoma (RCC) is the 10th most common cancer in Canada, with an estimated 8100 new cases and 1950 deaths from the disease annually.[1][1] Renal cell carcinoma accounts for more than 90% of kidney malignancies. Its incidence increases with age, with a global median age at
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Mashup Score: 20Advances in the management of renal cell carcinoma - 2 month(s) ago
KEY POINTS Renal cell carcinoma (RCC) is the 10th most common cancer in Canada, with an estimated 8100 new cases and 1950 deaths from the disease annually.[1][1] Renal cell carcinoma accounts for more than 90% of kidney malignancies. Its incidence increases with age, with a global median age at
Source: www.cmaj.caCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 19Advances in the management of renal cell carcinoma - 2 month(s) ago
KEY POINTS Renal cell carcinoma (RCC) is the 10th most common cancer in Canada, with an estimated 8100 new cases and 1950 deaths from the disease annually.[1][1] Renal cell carcinoma accounts for more than 90% of kidney malignancies. Its incidence increases with age, with a global median age at
Source: www.cmaj.caCategories: General Medicine News, Partners & KOLsTweet
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Mashup Score: 1Differential effect of ticagrelor versus clopidogrel by homocysteine levels on risk of recurrent stroke: a post hoc analysis of the CHANCE-2 trial - 3 month(s) ago
Background: Elevated homocysteine levels are associated with increased blood coagulation and platelet activity and may modulate the response to antiplatelet therapies. We aimed to investigate the effects of homocysteine levels on the efficacy and safety of ticagrelor–acetylsalicylic acid (ASA) versus clopidogrel–ASA among patients with minor stroke or transient ischemic attack who carried CYP2C19 loss-of-function alleles. Methods: We conducted a post hoc analysis of the CHANCE-2 (The Clopidogrel in High-risk Patients with Acute Nondisabling Cerebrovascular Events–II) trial. Participants were randomly assigned to treatment with ticagrelor–ASA or clopidogrel–ASA. We categorized participants into groups with elevated and non-elevated homocysteine levels, based on the median level. The primary efficacy outcome was recurrent stroke within 90-day follow-up. The primary safety outcome was severe or moderate bleeding within 90 days. Results: A total of 2740 participants were randomly assigned
Source: www.cmaj.caCategories: General Medicine News, Partners & KOLsTweet
Exercise as a treatment for depression https://t.co/T9n7Tsx3oF via @NTFabiano et al https://t.co/lUpsNYNaoF