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Mashup Score: 1
Xenotransplantation offers the potential to meet the critical need for heart and lung transplantation presently constrained by the current human donor organ supply. Much was learned over the past decades regarding gene editing to prevent the immune activation and inflammation that cause early organ injury, and strategies for maintenance of immunosuppression to promote longer-term xenograft survival. However, many scientific questions remain regarding further requirements for genetic modification of donor organs, appropriate contexts for xenotransplantation research (including nonhuman primates, recently deceased humans, and living human recipients), and risk of xenozoonotic disease transmission.
Source: www.amjtransplant.orgCategories: General Medicine News, Cardiology News and JournTweet
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Mashup Score: 29OPTN/SRTR 2023 Annual Data Report: Kidney - 2 month(s) ago
In 2023, the field of kidney transplantation faced both successes and challenges. A record 28,142 total kidney transplants were achieved in the United States, largely due to an increase in deceased donor kidney transplants (DDKTs). While the number of adult candidates listed for DDKT slightly increased, it remained below the level in 2019, with 11.4% of candidates waiting 5 years or more. Across racial and ethnic groups, Black adult candidates had the largest increase in DDKT rate in 2023, in parallel with the Organ Procurement and Transplantation Network policy to modify waiting time (implemented January 5, 2023).
Source: www.amjtransplant.orgCategories: General Medicine News, NephrologyTweet-
🙌🏾 Honored to be part of @UNOSNews /@SRTRNews 2023 #AnnualDataReport: #Kidney authorship team📖 🤝🏽#Teamwork | #DataDriven #KidneyTransplantation | #LivingDonation | #OrganUse | #Access | #Outcomes 📊@EpiSnyder @DonateLife💙💚 ·🆓 download @amjtransplant👇🏽: https://t.co/1pv4TbXaE8 https://t.co/o2T067UF54
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Mashup Score: 41Evaluation for genetic disease in kidney transplant candidates: A practice resource - 5 month(s) ago
The increasing availability of clinically approved genetic tests for kidney disease has spurred the growth in the use of these tests in kidney transplant practice. Neither the testing options nor the patient population where this should be deployed has been defined and its value in kidney transplant evaluation has not been demonstrated. Transplant providers may not always be aware of the limitations of genetic testing and may need guidance on comprehending test results and providing counsel, as many centers do not have easy access to a renal genetic counselor or a clinical geneticist.
Source: www.amjtransplant.orgCategories: General Medicine News, NephrologyTweet-
Excited to see this published from our @AST_KPCOP Genetics work group!!! Led by #ChristieThomas Evaluation for genetic disease in kidney transplant candidates: A practice resource. @KidneyPrince @TersMireille @GbadegesinLab @AST_info @amjtransplant https://t.co/PPkPk9JyHP
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Mashup Score: 6Donor-derived bartonellosis in Solid Organ Transplant recipients from unhoused donors in Alberta - 5 month(s) ago
Bartonella quintana (BQ) infection is rarely described to be transmitted through solid organ transplant (SOT). We report a cluster of donor-derived BQ infection and attack rate from Bartonella seropositive donors.Retrospective study of SOT recipients that received an organ from an unhoused deceased donor (UDD) in Alberta in 2022-2023. Serology testing for Bartonella was performed with Indirect Immunofluorescent Assay from UDD and recipients from UDD with positive serology. Titers ≥1:64 considered positive.
Source: www.amjtransplant.orgCategories: General Medicine News, NephrologyTweet-
Bartonella transmission with organ transplants - case series from Alberta in @amjtransplant https://t.co/Dc3DES6tFr #txid
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Mashup Score: 0American Journal of Transplantation - 10 month(s) ago
Nadim Mahmud, MD MS MPH MSCE Assistant Professor Hospital of the University of Pennsylvania, Philadelphia, PA, USA William Bernal, MD MS MPH MSCE Professor King’s College Hospital, London, UK Salvatore Piano, MD, PhD Assistant Professor MD MS MPH MSCE King’s College Hospital, London, UK This virtual issue delves into the multifaceted realm of Acute-on-Chronic Liver Failure (ACLF), a condition with extremely high short-term mortality that requires expert management and often consideration of liver transplan
Source: www.amjtransplant.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Learn from leading experts and researchers while they explore the immunopathogenesis underlying #ACLF https://t.co/xwcyx50b7o amjtransplant #ILTS2024 #transplantation #Livertransplantation #Liver AST_info ESOTtransplant SPLIT_TTS LTxJournal https://t.co/xsq3mpY35R
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Mashup Score: 13
Generative artificial intelligence (AI), a subset of machine learning that creates new content based on training data, has witnessed tremendous advances in recent years. Practical applications have been identified in healthcare in general, and there is significant opportunity in transplant medicine for generative AI to simplify tasks in research, medical education as well as clinical practice. Additionally, patients stand to benefit from patient education that is more readily provided by generative AI applications.
Source: www.amjtransplant.orgCategories: General Medicine News, General HCPsTweet-
Authors of this paper described practical applications about how generative AI could simplify tasks in research, medical education as well as clinical practice in transplant medicine. https://t.co/UYttNFDrsX https://t.co/C1CWw9hR5a
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Mashup Score: 0American Journal of Transplantation - 10 month(s) ago
Nadim Mahmud, MD MS MPH MSCE Assistant Professor Hospital of the University of Pennsylvania, Philadelphia, PA, USA William Bernal, MD MS MPH MSCE Professor King’s College Hospital, London, UK Salvatore Piano, MD, PhD Assistant Professor MD MS MPH MSCE King’s College Hospital, London, UK This virtual issue delves into the multifaceted realm of Acute-on-Chronic Liver Failure (ACLF), a condition with extremely high short-term mortality that requires expert management and often consideration of liver transplan
Source: www.amjtransplant.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Learn from leading experts and researchers while they explore the immunopathogenesis underlying #ACLF https://t.co/xwcyx50b7o amjtransplant #ILTS2024 #transplantation #Livertransplantation #Liver AST_info ESOTtransplant SPLIT_TTS LTxJournal https://t.co/xsq3mpY35R
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Mashup Score: 0American Journal of Transplantation - 11 month(s) ago
Nadim Mahmud, MD MS MPH MSCE Assistant Professor Hospital of the University of Pennsylvania, Philadelphia, PA, USA William Bernal, MD MS MPH MSCE Professor King’s College Hospital, London, UK Salvatore Piano, MD, PhD Assistant Professor MD MS MPH MSCE King’s College Hospital, London, UK This virtual issue delves into the multifaceted realm of Acute-on-Chronic Liver Failure (ACLF), a condition with extremely high short-term mortality that requires expert management and often consideration of liver transplan
Source: www.amjtransplant.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Learn from leading experts and researchers while they explore the immunopathogenesis underlying #ACLF https://t.co/xwcyx50b7o amjtransplant #ILTS2024 #transplantation #Livertransplantation #Liver AST_info ESOTtransplant SPLIT_TTS LTxJournal https://t.co/xsq3mpY35R
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Mashup Score: 0American Journal of Transplantation - 11 month(s) ago
Nadim Mahmud, MD MS MPH MSCE Assistant Professor Hospital of the University of Pennsylvania, Philadelphia, PA, USA William Bernal, MD MS MPH MSCE Professor King’s College Hospital, London, UK Salvatore Piano, MD, PhD Assistant Professor MD MS MPH MSCE King’s College Hospital, London, UK This virtual issue delves into the multifaceted realm of Acute-on-Chronic Liver Failure (ACLF), a condition with extremely high short-term mortality that requires expert management and often consideration of liver transplan
Source: www.amjtransplant.orgCategories: General Medicine News, Allergy-ImmunologyTweet-
Learn from leading experts and researchers while they explore the immunopathogenesis underlying #ACLF https://t.co/xwcyx50b7o amjtransplant #ILTS2024 #transplantation #Livertransplantation #Liver AST_info ESOTtransplant SPLIT_TTS LTxJournal https://t.co/xsq3mpY35R
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Mashup Score: 10Impact of deceased organ donor marijuana use on donor culture positivity and solid organ transplant recipient outcomes - 1 year(s) ago
With the increasing prevalence of marijuana use in the U.S., many deceased organ donors have a history of marijuana use, raising concerns about infectious risks to transplant recipients. We performed a multicenter retrospective cohort study in which exposed donors were those with recent marijuana use (in the prior 12 months) and unexposed donors were those with no recent marijuana use. Primary outcomes included (1) positive donor cultures for bacteria or fungi, (2) recipient infection due to bacteria or fungi within 3 months post-transplant, and (3) recipient graft failure or death within 12 months post-transplant.
Source: www.amjtransplant.orgCategories: General Medicine News, Infectious DiseaseTweet-
1/2 February 2024 @AST_info @AST_IDCOP Article of the Month - Impact of deceased organ donor marijuana use on donor culture positivity and solid organ transplant recipient outcomes https://t.co/NTVeJHUB3G
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We continue to celebrate #WomensHistoryMonth with Dr. Kiran Khush, the 1st author of "Research opportunities and ethical considerations for heart and lung xenotransplantation research: A report from the National Heart, Lung, and Blood Institute workshop" https://t.co/vPx2XqOypQ https://t.co/GjQOWP9W2S