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Mashup Score: 279Magnesium Disorders: Core Curriculum 2024 - 5 day(s) ago
Magnesium is ubiquitous in nature. It sits at the origin of the food chain, occupying the center of chlorophyl in plants. In humans, magnesium is critical to diverse molecular and catalytic processes, including energy transfer and maintenance of the genome. Despite its abundance, hypomagnesemia is common and often goes undiagnosed. This is in spite of epidemiologic data linking low magnesium with chronic diseases including diabetes mellitus. Clinically significant hypermagnesemia is encountered less frequently, but the presentation may be dramatic.
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Mashup Score: 0
Atrial fibrillation (AF) is the most common sustained arrythmia in the general population and an independent risk factor for death.1,2 AF occurs in up to 18% of patients with chronic kidney disease.3 The association of lower glomerular filtration rate (GFR) as a risk factor for incident AF is influenced by the method used to assess the estimated GFR (eGFR), which has implications for clinical practice.
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Mashup Score: 5Development and Validation of the Rating of CKD Knowledge Among Older Adults (Know-CKD) with Kidney Failure - 5 day(s) ago
Few older adults with kidney failure engage in shared decision-making (SDM) for kidney replacement therapy. Absence of instruments assessing SDM-relevant knowledge domains may contribute to this. We assessed the reliability and validity of a new instrument, the Rating of CKD Knowledge Older Adults (Know-CKD).
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Mashup Score: 5Association of Race and Ethnicity With High Longevity Deceased Donor Kidney Transplantation Under the US Kidney Allocation System - 6 day(s) ago
The US Kidney Allocation System (KAS) prioritizes candidates with ≤20% Estimated Post-Transplant Survival (EPTS) for high longevity kidneys defined by a ≤20% Kidney Donor Profile Index (KDPI). Use of EPTS in the KAS deprioritizes candidates with older age, diabetes, and longer dialysis durations. We assessed whether this use also disadvantages racial-ethnic minority candidates, who are younger but more likely to have diabetes and longer durations of kidney failure requiring dialysis.
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Mashup Score: 3The Importance of Hope for Patients With CKD - 6 day(s) ago
Receiving a diagnosis of chronic kidney disease (CKD) can be devasting to patients and their families. Patients with CKD and their care partners often face a lifetime of daily battles resulting from numerous symptoms and the disease’s complex pathophysiology. Many face progressive decline in kidney function and the possible need for kidney replacement therapy.
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Mashup Score: 1
Cognitive impairment is pervasive among kidney failure patients, reducing the chance of listing for kidney transplant (KT)1,2 and increasing time until KT for those who are listed.2 Yet, KT is the preferred form of kidney replacement therapy3 and has been shown to improve cognition.2,4,5 Cognitive impairment also has major implications on patients post-KT, impacting their health, graft survival, quality of life, and risk of mortality.2,5,6 While transplant institutes consider cognition when determining transplant eligibility, both patients and clinical experts argue that cognitive impairment alone should not be a contraindication for KT,7,8 particularly if certain cognitive domains can recover post-KT.
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Mashup Score: 17American Journal of Kidney Diseases - 7 day(s) ago
These articles highlight various types of disparities that impact patients with kidney diseases and call attention to more research that is necessary to achieve the goal of global health
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Mashup Score: 161
Magnesium (Mg2+), also known as “the forgotten ion,” is the second most abundant intracellular cation and is essential in a broad range of intracellular physiological and biochemical reactions. Its deficiency, hypomagnesemia (Mg2+<1.8mg/dL), is a prevalent condition and routinely poses challenges in its management in clinical practice. Sodium/glucose cotransporter 2 (SGLT2) inhibitors have emerged as a new class of drugs with treating hypomagnesemia as their unique extraglycemic benefit. The beneficial effect of SGLT2 inhibitors on magnesium balance in patients with diabetes with or without hypomagnesemia has been noted as a class effect in recent meta-analysis data from randomized clinical trials.
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Mashup Score: 29
Hyponatremia is the most common electrolyte disorder and is associated with significant morbidity and mortality. This study investigated neurocognitive impairment, brain volume, and alterations in MRI-based measures of cerebral function in patients before and after treatment for hyponatremia.
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Mashup Score: 7Living With a Rare Glomerular Disease: A Call to Action for Early Diagnosis and Innovation in Treatment - 8 day(s) ago
My Story (Antonia’s Perspective)
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Magnesium Disorders: Core Curriculum 2024 https://t.co/i4N3VUyHCh (FREE) @EAAdomako @AlanYuNeph @KUNeph https://t.co/n6P7WPGkZu